rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P07267 | 405 | CARP_YEAST Saccharopepsin OS=Saccharomyces ce... | 405 | 0 | 833 | 100 | 100 | GO:0000328; C:fungal-type vacuole lumen; TAS:SGD.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009267; P:cellular response to starvation; IMP:SGD.::GO:0016237; P:microautophagy; IMP:SGD.::GO:0051603; P:proteolysis involved in cellular protein catabolic process; IMP:SGD. | 2 | P10977 | 419 | CARPV_CANAX Vacuolar aspartic protease OS=Can... | 415 | 0 | 547 | 67 | 76 | GO:0005773; C:vacuole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 3 | O42630 | 398 | CARP_ASPFU Vacuolar protease A OS=A1100) (Asp... | 399 | 0 | 522 | 63 | 80 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 4 | D4B385 | 400 | CARP_ARTBC Probable vacuolar protease A OS=(T... | 385 | 4e-173 | 496 | 59 | 77 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 5 | D4DEN7 | 400 | CARP_TRIVH Probable vacuolar protease A OS=Tr... | 385 | 3e-172 | 494 | 59 | 77 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 6 | Q01294 | 396 | CARP_NEUCR Vacuolar protease A OS=1257 / FGSC... | 399 | 6e-168 | 483 | 57 | 75 | GO:0005773; C:vacuole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 7 | C5FS55 | 395 | CARP_ARTOC Vacuolar protease A OS=canis). GN=... | 385 | 5e-166 | 478 | 58 | 75 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 8 | Q03168 | 387 | ASPP_AEDAE Lysosomal aspartic protease OS=Aed... | 376 | 7e-105 | 322 | 46 | 61 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 9 | O93428 | 396 | CATD_CHIHA Cathepsin D OS=rhinoceratus hamatu... | 405 | 7e-96 | 299 | 43 | 58 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IDA:UniProtKB. | 10 | Q05744 | 398 | CATD_CHICK Cathepsin D OS=Gallus gallus (Chic... | 330 | 6e-94 | 294 | 46 | 62 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 11 | P07339 | 412 | CATD_HUMAN Cathepsin D OS=Homo sapiens (Human... | 365 | 2e-93 | 293 | 44 | 58 | GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 12 | Q9DEX3 | 396 | CATD_CLUHA Cathepsin D OS=Clupea harengus (At... | 329 | 4e-92 | 289 | 45 | 62 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 13 | Q805F3 | 397 | CATEA_XENLA Cathepsin E-A OS=Xenopus laevis (... | 326 | 1e-90 | 286 | 44 | 61 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 14 | Q805F2 | 397 | CATEB_XENLA Cathepsin E-B OS=Xenopus laevis (... | 328 | 2e-90 | 285 | 44 | 61 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 15 | P70269 | 397 | CATE_MOUSE Cathepsin E OS=Mus musculus (Mouse... | 394 | 2e-90 | 285 | 41 | 57 | GO:0005768; C:endosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:MGI. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 16 | P18242 | 410 | CATD_MOUSE Cathepsin D OS=Mus musculus (Mouse... | 339 | 5e-90 | 284 | 45 | 60 | GO:0005764; C:lysosome; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:MGI. | | | | | | | | | | GO:0000045; P:autophagic vacuole assembly; IMP:MGI.::GO:0006508; P:proteolysis; IC:MGI. | 17 | P24268 | 407 | CATD_RAT Cathepsin D OS=Rattus norvegicus (Ra... | 335 | 1e-89 | 283 | 45 | 61 | GO:0005764; C:lysosome; IDA:RGD.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0042277; F:peptide binding; IDA:RGD. | | | | | | | | | | GO:0006914; P:autophagy; IEP:RGD.::GO:0006508; P:proteolysis; IDA:RGD. | 18 | Q4LAL9 | 410 | CATD_CANFA Cathepsin D OS=Canis familiaris (D... | 354 | 4e-89 | 282 | 43 | 58 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 19 | P16228 | 398 | CATE_RAT Cathepsin E OS=Rattus norvegicus (Ra... | 394 | 1e-88 | 280 | 40 | 57 | GO:0005768; C:endosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.::GO:0016540; P:protein autoprocessing; IMP:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 20 | Q9GMY4 | 389 | PEPC_SORUN Gastricsin OS=Sorex unguiculatus (... | 349 | 4e-88 | 279 | 41 | 58 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 21 | O09043 | 419 | NAPSA_MOUSE Napsin-A OS=Mus musculus (Mouse).... | 382 | 5e-88 | 279 | 41 | 57 | GO:0042599; C:lamellar body; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033619; P:membrane protein proteolysis; IMP:UniProtKB. | 22 | P80209 | 390 | CATD_BOVIN Cathepsin D OS=Bos taurus (Bovine)... | 338 | 3e-87 | 276 | 43 | 60 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 23 | P14091 | 401 | CATE_HUMAN Cathepsin E OS=Homo sapiens (Human... | 334 | 4e-87 | 276 | 44 | 60 | GO:0005768; C:endosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.::GO:0007586; P:digestion; TAS:ProtInc.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 24 | O76856 | 383 | CATD_DICDI Cathepsin D OS=Dictyostelium disco... | 404 | 4e-87 | 276 | 38 | 56 | GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 25 | Q800A0 | 397 | CATE_LITCT Cathepsin E OS=Lithobates catesbei... | 326 | 1e-86 | 275 | 43 | 60 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 26 | P20142 | 388 | PEPC_HUMAN Gastricsin OS=Homo sapiens (Human)... | 322 | 2e-86 | 275 | 42 | 60 | GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc. | | | | | | | | | | GO:0007586; P:digestion; TAS:ProtInc.::GO:0006508; P:proteolysis; TAS:ProtInc. | 27 | P28713 | 387 | PEPA4_RABIT Pepsin II-4 OS=Oryctolagus cunicu... | 383 | 3e-86 | 274 | 38 | 56 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 28 | P81498 | 389 | PEPC_SUNMU Gastricsin OS=Suncus murinus (Asia... | 322 | 3e-86 | 274 | 40 | 60 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 29 | Q9GMY3 | 389 | PEPC_RHIFE Gastricsin OS=Rhinolophus ferrumeq... | 322 | 7e-86 | 273 | 41 | 61 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 30 | P03955 | 377 | PEPC_MACFU Gastricsin OS=Macaca fuscata fusca... | 322 | 8e-86 | 272 | 42 | 60 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 31 | P25796 | 391 | CATE_CAVPO Cathepsin E OS=Cavia porcellus (Gu... | 329 | 3e-85 | 271 | 44 | 60 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |