Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL154C
Length:
405
Number of sequences:
5887
Description:
YPL154C PEP4 SGDID:S000006075, Chr XVI from 260931-259714, Genome Release 64-1-1, reverse complement, Verified ORF, "Vacuolar aspartyl protease (proteinase A), required for the posttranslational precursor maturation of vacuolar proteinases; important for protein turnover after oxidative damage; synthesized as a zymogen, self-activates"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P07267    405   CARP_YEAST Saccharopepsin OS=Saccharomyces ce...4050     833     100     100GO:0000328; C:fungal-type vacuole lumen; TAS:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009267; P:cellular response to starvation; IMP:SGD.::GO:0016237; P:microautophagy; IMP:SGD.::GO:0051603; P:proteolysis involved in cellular protein catabolic process; IMP:SGD.
2P10977    419   CARPV_CANAX Vacuolar aspartic protease OS=Can...4150     547     67     76GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
3O42630    398   CARP_ASPFU Vacuolar protease A OS=A1100) (Asp...3990     522     63     80GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
4D4B385    400   CARP_ARTBC Probable vacuolar protease A OS=(T...3854e-173     496     59     77GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
5D4DEN7    400   CARP_TRIVH Probable vacuolar protease A OS=Tr...3853e-172     494     59     77GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
6Q01294    396   CARP_NEUCR Vacuolar protease A OS=1257 / FGSC...3996e-168     483     57     75GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
7C5FS55    395   CARP_ARTOC Vacuolar protease A OS=canis). GN=...3855e-166     478     58     75GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
8Q03168    387   ASPP_AEDAE Lysosomal aspartic protease OS=Aed...3767e-105     322     46     61GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
9O93428    396   CATD_CHIHA Cathepsin D OS=rhinoceratus hamatu...4057e-96     299     43     58GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.
GO:0006508; P:proteolysis; IDA:UniProtKB.
10Q05744    398   CATD_CHICK Cathepsin D OS=Gallus gallus (Chic...3306e-94     294     46     62GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
11P07339    412   CATD_HUMAN Cathepsin D OS=Homo sapiens (Human...3652e-93     293     44     58GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc.
GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
12Q9DEX3    396   CATD_CLUHA Cathepsin D OS=Clupea harengus (At...3294e-92     289     45     62GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
13Q805F3    397   CATEA_XENLA Cathepsin E-A OS=Xenopus laevis (...3261e-90     286     44     61GO:0005768; C:endosome; ISS:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.
GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
14Q805F2    397   CATEB_XENLA Cathepsin E-B OS=Xenopus laevis (...3282e-90     285     44     61GO:0005768; C:endosome; ISS:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB.
GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
15P70269    397   CATE_MOUSE Cathepsin E OS=Mus musculus (Mouse...3942e-90     285     41     57GO:0005768; C:endosome; IDA:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:MGI.
GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
16P18242    410   CATD_MOUSE Cathepsin D OS=Mus musculus (Mouse...3395e-90     284     45     60GO:0005764; C:lysosome; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0004190; F:aspartic-type endopeptidase activity; IDA:MGI.
GO:0000045; P:autophagic vacuole assembly; IMP:MGI.::GO:0006508; P:proteolysis; IC:MGI.
17P24268    407   CATD_RAT Cathepsin D OS=Rattus norvegicus (Ra...3351e-89     283     45     61GO:0005764; C:lysosome; IDA:RGD.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0042277; F:peptide binding; IDA:RGD.
GO:0006914; P:autophagy; IEP:RGD.::GO:0006508; P:proteolysis; IDA:RGD.
18Q4LAL9    410   CATD_CANFA Cathepsin D OS=Canis familiaris (D...3544e-89     282     43     58GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
19P16228    398   CATE_RAT Cathepsin E OS=Rattus norvegicus (Ra...3941e-88     280     40     57GO:0005768; C:endosome; IDA:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.
GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.::GO:0016540; P:protein autoprocessing; IMP:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
20Q9GMY4    389   PEPC_SORUN Gastricsin OS=Sorex unguiculatus (...3494e-88     279     41     58GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
21O09043    419   NAPSA_MOUSE Napsin-A OS=Mus musculus (Mouse)....3825e-88     279     41     57GO:0042599; C:lamellar body; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0033619; P:membrane protein proteolysis; IMP:UniProtKB.
22P80209    390   CATD_BOVIN Cathepsin D OS=Bos taurus (Bovine)...3383e-87     276     43     60GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
23P14091    401   CATE_HUMAN Cathepsin E OS=Homo sapiens (Human...3344e-87     276     44     60GO:0005768; C:endosome; IDA:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.
GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.::GO:0007586; P:digestion; TAS:ProtInc.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
24O76856    383   CATD_DICDI Cathepsin D OS=Dictyostelium disco...4044e-87     276     38     56GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
25Q800A0    397   CATE_LITCT Cathepsin E OS=Lithobates catesbei...3261e-86     275     43     60GO:0005768; C:endosome; ISS:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB.
GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
26P20142    388   PEPC_HUMAN Gastricsin OS=Homo sapiens (Human)...3222e-86     275     42     60GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc.
GO:0007586; P:digestion; TAS:ProtInc.::GO:0006508; P:proteolysis; TAS:ProtInc.
27P28713    387   PEPA4_RABIT Pepsin II-4 OS=Oryctolagus cunicu...3833e-86     274     38     56GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
28P81498    389   PEPC_SUNMU Gastricsin OS=Suncus murinus (Asia...3223e-86     274     40     60GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
29Q9GMY3    389   PEPC_RHIFE Gastricsin OS=Rhinolophus ferrumeq...3227e-86     273     41     61GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
30P03955    377   PEPC_MACFU Gastricsin OS=Macaca fuscata fusca...3228e-86     272     42     60GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
31P25796    391   CATE_CAVPO Cathepsin E OS=Cavia porcellus (Gu...3293e-85     271     44     60GO:0005768; C:endosome; ISS:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB.
GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
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