Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL140C
Length:
506
Number of sequences:
5887
Description:
YPL140C MKK2 SGDID:S000006061, Chr XVI from 289034-287514, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
961P26817    689   ARBK1_RAT Beta-adrenergic receptor kinase 1 O...2572e-19     95.5     29     47GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0030424; C:axon; IDA:RGD.::GO:0016323; C:basolateral plasma membrane; IDA:RGD.::GO:0005901; C:caveola; IDA:RGD.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0043198; C:dendritic shaft; IDA:RGD.::GO:0043197; C:dendritic spine; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0045202; C:synapse; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047696; F:beta-adrenergic receptor kinase activity; IDA:RGD.::GO:0004703; F:G-protein coupled receptor kinase activity; IDA:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007568; P:aging; IEP:RGD.::GO:0002029; P:desensitization of G-protein coupled receptor protein signaling pathway; IDA:BHF-UCL.::GO:0042699; P:follicle-stimulating hormone signaling pathway; IDA:RGD.::GO:0033605; P:positive regulation of catecholamine secretion; IDA:BHF-UCL.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IDA:RGD.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
962P62205    598   PLK1_XENTR Serine/threonine-protein kinase PL...2022e-19     95.1     29     50GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000776; C:kinetochore; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB.
963Q9HGY5    326   PHO85_CANAX Negative regulator of the PHO sys...2012e-19     92.8     31     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
964Q9I958    361   MK14B_CYPCA Mitogen-activated protein kinase ...2132e-19     93.2     30     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
965Q2QY53    438   CIPKW_ORYSJ CBL-interacting protein kinase 32...2032e-19     94.4     32     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
966P28482    360   MK01_HUMAN Mitogen-activated protein kinase 1...2112e-19     93.2     31     47GO:0005901; C:caveola; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; TAS:ProtInc.::GO:0019902; F:phosphatase binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0070371; P:ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
967Q99MK8    689   ARBK1_MOUSE Beta-adrenergic receptor kinase 1...2572e-19     95.5     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047696; F:beta-adrenergic receptor kinase activity; IEA:EC.::GO:0004703; F:G-protein coupled receptor kinase activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0002029; P:desensitization of G-protein coupled receptor protein signaling pathway; IMP:MGI.::GO:0007507; P:heart development; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MGI.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
968P49139    366   MAPK2_RABIT MAP kinase-activated protein kina...2942e-19     93.2     28     47GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0006954; P:inflammatory response; ISS:UniProtKB.::GO:0044351; P:macropinocytosis; ISS:UniProtKB.::GO:0032675; P:regulation of interleukin-6 production; ISS:UniProtKB.::GO:0032680; P:regulation of tumor necrosis factor production; ISS:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0002224; P:toll-like receptor signaling pathway; ISS:UniProtKB.
969O96821    288   CDC2H_PLAKH Cell division control protein 2 h...2022e-19     92.4     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
970Q25378    658   KPC1_LYTPI Protein kinase C OS=Lytechinus pic...2192e-19     95.1     27     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
971Q5W736    457   CIPKI_ORYSJ CBL-interacting protein kinase 18...2102e-19     94.4     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
972A1DES4    377   MPKC_NEOFI Mitogen-activated protein kinase m...2022e-19     93.6     33     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
973P12688    680   YPK1_YEAST Serine/threonine-protein kinase YP...2122e-19     95.1     31     49GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005829; C:cytosol; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0070941; P:eisosome assembly; IGI:SGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0061093; P:negative regulation of phospholipid translocation; IMP:SGD.::GO:0046777; P:protein autophosphorylation; IDA:SGD.
974Q9XBQ0    547   PKN3_MYXXA Serine/threonine-protein kinase pk...2732e-19     94.7     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
975Q0JI49    502   CIPKB_ORYSJ CBL-interacting protein kinase 11...2042e-19     94.7     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
976Q55GG4    2230   Y9847_DICDI Probable serine/threonine-protein...2982e-19     95.9     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
977P21146    689   ARBK1_BOVIN Beta-adrenergic receptor kinase 1...2572e-19     95.1     29     47GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0016020; C:membrane; IDA:BHF-UCL.
GO:0031694; F:alpha-2A adrenergic receptor binding; IPI:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047696; F:beta-adrenergic receptor kinase activity; IEA:EC.::GO:0031755; F:Edg-2 lysophosphatidic acid receptor binding; ISS:UniProtKB.::GO:0004703; F:G-protein coupled receptor kinase activity; IDA:BHF-UCL.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; IDA:BHF-UCL.::GO:0002031; P:G-protein coupled receptor internalization; IDA:UniProtKB.::GO:0007507; P:heart development; ISS:AgBase.::GO:0006886; P:intracellular protein transport; IMP:BHF-UCL.::GO:0045988; P:negative regulation of striated muscle contraction; IMP:BHF-UCL.::GO:0003108; P:negative regulation of the force of heart contraction by chemical signal; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
978Q5RCH1    297   CDK1_PONAB Cyclin-dependent kinase 1 OS=Pongo...2122e-19     92     29     50GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
979P13678    634   KPC3_DROME Protein kinase C OS=Drosophila mel...2042e-19     95.1     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0007030; P:Golgi organization; IMP:FlyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034389; P:lipid particle organization; IMP:FlyBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:FlyBase.::GO:0045471; P:response to ethanol; IDA:FlyBase.
980P25098    689   ARBK1_HUMAN Beta-adrenergic receptor kinase 1...2572e-19     95.1     29     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0031694; F:alpha-2A adrenergic receptor binding; ISS:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047696; F:beta-adrenergic receptor kinase activity; IEA:EC.::GO:0031755; F:Edg-2 lysophosphatidic acid receptor binding; IDA:UniProtKB.::GO:0004703; F:G-protein coupled receptor kinase activity; ISS:BHF-UCL.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.::GO:0002029; P:desensitization of G-protein coupled receptor protein signaling pathway; ISS:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; ISS:BHF-UCL.::GO:0045988; P:negative regulation of striated muscle contraction; IMP:BHF-UCL.::GO:0003108; P:negative regulation of the force of heart contraction by chemical signal; IMP:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:BHF-UCL.::GO:0033605; P:positive regulation of catecholamine secretion; ISS:BHF-UCL.::GO:0031623; P:receptor internalization; IDA:UniProtKB.::GO:0007217; P:tachykinin receptor signaling pathway; IDA:BHF-UCL.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
981Q2QYM3    439   CIPKE_ORYSJ CBL-interacting protein kinase 14...2162e-19     94     30     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
982Q54VC0    418   Y9865_DICDI Probable serine/threonine-protein...1382e-19     94     36     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
983Q9LRP3    467   Y3174_ARATH Probable receptor-like protein ki...2712e-19     94.4     28     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
984Q2RBF0    434   CIPKF_ORYSJ CBL-interacting protein kinase 15...2162e-19     94     30     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
985P63086    358   MK01_RAT Mitogen-activated protein kinase 1 O...2112e-19     92.8     31     47GO:0033267; C:axon part; IDA:RGD.::GO:0005901; C:caveola; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0032839; C:dendrite cytoplasm; IDA:RGD.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0043204; C:perikaryon; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:RGD.::GO:0008134; F:transcription factor binding; IPI:RGD.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000189; P:MAPK import into nucleus; IDA:RGD.::GO:0030335; P:positive regulation of cell migration; IEP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IEP:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IEP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0043627; P:response to estrogen stimulus; IDA:RGD.::GO:0009636; P:response to toxin; IDA:RGD.::GO:0019233; P:sensory perception of pain; IMP:UniProtKB.
986P63085    358   MK01_MOUSE Mitogen-activated protein kinase 1...2112e-19     92.8     31     47GO:0005901; C:caveola; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0031143; C:pseudopodium; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:MGI.::GO:0001784; F:phosphotyrosine binding; IMP:MGI.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0050853; P:B cell receptor signaling pathway; IDA:MGI.::GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0019858; P:cytosine metabolic process; IDA:MGI.::GO:0060716; P:labyrinthine layer blood vessel development; IMP:MGI.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IDA:MGI.::GO:0045596; P:negative regulation of cell differentiation; IGI:MGI.::GO:0009887; P:organ morphogenesis; IDA:MGI.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:MGI.::GO:0043330; P:response to exogenous dsRNA; IDA:MGI.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; NAS:UniProtKB.
987P54644    444   KRAC_DICDI RAC family serine/threonine-protei...2723e-19     94     28     46GO:0005938; C:cell cortex; IDA:dictyBase.
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0019887; F:protein kinase regulator activity; TAS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase.
GO:0006935; P:chemotaxis; TAS:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; TAS:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; TAS:dictyBase.::GO:0031036; P:myosin II filament assembly; TAS:dictyBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:dictyBase.::GO:0045859; P:regulation of protein kinase activity; TAS:dictyBase.
988P49137    400   MAPK2_HUMAN MAP kinase-activated protein kina...2943e-19     93.6     28     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; TAS:ProtInc.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:UniProtKB.::GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:BHF-UCL.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0006954; P:inflammatory response; ISS:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0019370; P:leukotriene biosynthetic process; TAS:Reactome.::GO:0044351; P:macropinocytosis; ISS:UniProtKB.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0006692; P:prostanoid metabolic process; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0032675; P:regulation of interleukin-6 production; ISS:UniProtKB.::GO:0032680; P:regulation of tumor necrosis factor production; IDA:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
989P38070    525   YPK3_YEAST AGC kinase YPK3 OS=Saccharomyces c...2903e-19     94.4     26     44GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
990P26696    361   MK01_XENLA Mitogen-activated protein kinase 1...2093e-19     92.8     32     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
991Q54TA3    773   MRKC_DICDI Probable serine/threonine-protein ...2023e-19     95.1     30     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
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