Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL139C
Length:
460
Number of sequences:
5887
Description:
YPL139C UME1 SGDID:S000006060, Chr XVI from 291051-289669, Genome Release 64-1-1, reverse complement, Verified ORF, "Negative regulator of meiosis, required for repression of a subset of meiotic genes during vegetative growth, binding of histone deacetylase Rpd3p required for activity, contains a NEE box and a WD repeat motif; homologous with Wtm1p, Wtm2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q03010    460   UME1_YEAST Transcriptional regulatory protein...4600     944     100     100GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0033698; C:Rpd3L complex; IDA:SGD.::GO:0070210; C:Rpd3L-Expanded complex; IDA:SGD.::GO:0032221; C:Rpd3S complex; IDA:SGD.
GO:0003714; F:transcription corepressor activity; IDA:SGD.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0031939; P:negative regulation of chromatin silencing at telomere; IMP:SGD.::GO:0016479; P:negative regulation of transcription from RNA polymerase I promoter; IMP:SGD.::GO:0061408; P:positive regulation of transcription from RNA polymerase II promoter in response to heat stress; IMP:SGD.::GO:0040020; P:regulation of meiosis; IGI:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2Q12206    467   WTM2_YEAST Transcriptional modulator WTM2 OS=...4461e-101     318     40     58GO:0005634; C:nucleus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:SGD.::GO:0003714; F:transcription corepressor activity; IDA:SGD.
GO:0034629; P:cellular protein complex localization; IMP:SGD.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IMP:SGD.
3Q12363    437   WTM1_YEAST Transcriptional modulator WTM1 OS=...4451e-99     312     40     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003714; F:transcription corepressor activity; IDA:SGD.
GO:0051457; P:maintenance of protein location in nucleus; IMP:SGD.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q54SD4    423   RBBD_DICDI Probable histone-binding protein r...3160.000001     54.3     23     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5P0CS36    435   HAT2_CRYNJ Histone acetyltransferase type B s...4590.0001     48.1     20     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
6P0CS37    435   HAT2_CRYNB Histone acetyltransferase type B s...4590.0001     48.1     20     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
7Q6FT96    711   MDV1_CANGA Mitochondrial division protein 1 O...850.009     42.4     27     49GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
8Q8NFH3    380   NUP43_HUMAN Nucleoporin Nup43 OS=Homo sapiens...2330.009     42     22     38GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031080; C:Nup107-160 complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0010827; P:regulation of glucose transport; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
9Q6C7Q4    452   HAT2_YARLI Histone acetyltransferase type B s...4560.011     41.6     19     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
10P36130    643   CAF4_YEAST CCR4-associated factor 4 OS=Saccha...1000.011     42     29     46GO:0030014; C:CCR4-NOT complex; IDA:SGD.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0000266; P:mitochondrial fission; IMP:SGD.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:SGD.
11Q8SRK1    384   HAT2_ENCCU Histone acetyltransferase type B s...202.9     33.9     65     85GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
12Q04225    511   RRB1_YEAST Ribosome assembly protein RRB1 OS=...2070.017     41.2     24     41GO:0005730; C:nucleolus; IDA:SGD.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
13A6ZZZ8    645   CAF4_YEAS7 CCR4-associated factor 4 OS=Saccha...1000.02     41.2     28     46GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
14P59235    380   NUP43_MOUSE Nucleoporin Nup43 OS=Mus musculus...1720.026     40.4     24     38GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0031080; C:Nup107-160 complex; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
15Q54ED4    482   GRWD1_DICDI Glutamate-rich WD repeat-containi...640.11     38.5     31     52GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
16Q6CB13    565   MDV1_YARLI Mitochondrial division protein 1 O...610.13     38.5     30     48GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
17P90648    732   MHCKB_DICDI Myosin heavy chain kinase B OS=Di...1560.13     38.5     26     44GO:0005826; C:actomyosin contractile ring; IDA:dictyBase.
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0016905; F:myosin heavy chain kinase activity; IDA:dictyBase.::GO:0045159; F:myosin II binding; IPI:dictyBase.
GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0031037; P:myosin II filament disassembly; IMP:dictyBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.
18Q9BQ67    446   GRWD1_HUMAN Glutamate-rich WD repeat-containi...780.15     38.1     27     50GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
19Q810D6    446   GRWD1_MOUSE Glutamate-rich WD repeat-containi...780.15     38.1     28     51GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
20Q5QP82    559   DCA10_HUMAN DDB1- and CUL4-associated factor ...240.22     37.7     54     75GO:0080008; C:CUL4 RING ubiquitin ligase complex; IDA:UniProtKB.
GO:0016567; P:protein ubiquitination; IC:UniProtKB.
21Q5FW06    457   DCA10_XENTR DDB1- and CUL4-associated factor ...1410.25     37.4     23     41GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:UniProtKB.
22Q6NWH1    508   DCA10_DANRE DDB1- and CUL4-associated factor ...240.25     37.4     54     75GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:UniProtKB.
23Q8AVS9    457   DCA10_XENLA DDB1- and CUL4-associated factor ...1410.28     37.4     24     41GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:UniProtKB.
24A2AKB9    566   DCA10_MOUSE DDB1- and CUL4-associated factor ...240.28     37.4     54     75GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:UniProtKB.
25Q6CJ50    705   MDV1_KLULA Mitochondrial division protein 1 O...870.33     37.4     29     44GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
26Q9SU78    487   MSI5_ARATH WD-40 repeat-containing protein MS...800.33     37     23     46GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27Q3SWX8    425   RBBP7_BOVIN Histone-binding protein RBBP7 OS=...970.41     36.6     21     48GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.::GO:0016581; C:NuRD complex; ISS:UniProtKB.
GO:0070370; P:cellular heat acclimation; ISS:UniProtKB.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28Q71UF4    425   RBBP7_RAT Histone-binding protein RBBP7 OS=Ra...970.43     36.6     21     48GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.::GO:0016581; C:NuRD complex; ISS:UniProtKB.
GO:0070370; P:cellular heat acclimation; ISS:UniProtKB.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29Q4R304    425   RBBP7_MACFA Histone-binding protein RBBP7 OS=...970.43     36.6     21     48GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.::GO:0016581; C:NuRD complex; ISS:UniProtKB.
GO:0070370; P:cellular heat acclimation; ISS:UniProtKB.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30Q16576    425   RBBP7_HUMAN Histone-binding protein RBBP7 OS=...970.43     36.6     21     48GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB.::GO:0016581; C:NuRD complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0070370; P:cellular heat acclimation; IDA:UniProtKB.::GO:0034080; P:CenH3-containing nucleosome assembly at centromere; TAS:Reactome.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31Q60973    425   RBBP7_MOUSE Histone-binding protein RBBP7 OS=...970.44     36.6     21     48GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.::GO:0016581; C:NuRD complex; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.
GO:0070370; P:cellular heat acclimation; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; TAS:MGI.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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