UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YPL135W

Length:

165

Number of sequences:

5887

Description:

YPL135W ISU1 SGDID:S000006056, Chr XVI from 297553-298050, Genome Release 64-1-1, Verified ORF, "Conserved protein of the mitochondrial matrix, performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); isu1 isu2 double mutant is inviable"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q03020	165	ISU1_YEAST Iron sulfur cluster assembly prote...	165	7e-119	339	100	100	GO:0005759; C:mitochondrial matrix; IDA:SGD.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0008198; F:ferrous iron binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006879; P:cellular iron ion homeostasis; IMP:SGD.::GO:0016226; P:iron-sulfur cluster assembly; IMP:SGD.::GO:0002098; P:tRNA wobble uridine modification; IGI:SGD.
2	Q6FJY3	213	ISU1_CANGA Iron sulfur cluster assembly prote...	153	4e-87	261	84	90	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
3	Q75C07	154	ISU1_ASHGO Iron sulfur cluster assembly prote...	151	2e-81	244	79	87	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
4	Q12056	156	ISU2_YEAST Iron sulfur cluster assembly prote...	161	2e-81	244	74	87	GO:0005759; C:mitochondrial matrix; IDA:SGD.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0006879; P:cellular iron ion homeostasis; IMP:SGD.::GO:0016226; P:iron-sulfur cluster assembly; IMP:SGD.::GO:0002098; P:tRNA wobble uridine modification; IGI:SGD.
5	Q6CRQ9	180	ISU1_KLULA Iron sulfur cluster assembly prote...	133	1e-80	243	86	94	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
6	Q6BGU0	179	ISU1_DEBHA Iron sulfur cluster assembly prote...	160	3e-73	224	69	86	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
7	Q6CFQ0	181	ISU1_YARLI Iron sulfur cluster assembly prote...	157	3e-67	209	68	82	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
8	Q9UTC6	192	ISU1_SCHPO Iron sulfur cluster assembly prote...	156	7e-67	208	65	81	GO:0005759; C:mitochondrial matrix; ISS:PomBase.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IDA:PomBase.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0006879; P:cellular iron ion homeostasis; IMP:PomBase.::GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0016226; P:iron-sulfur cluster assembly; IMP:PomBase.
9	O49627	167	ISU1_ARATH Iron-sulfur cluster assembly prote...	126	2e-65	203	75	83	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; ISS:TAIR.
									GO:0016226; P:iron-sulfur cluster assembly; IGI:TAIR.
10	Q9ZD61	131	NIFU_RICPR NifU-like protein OS=Rickettsia pr...	126	5e-63	196	75	85
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
11	P0ACD7	128	NIFU_SHIFL NifU-like protein OS=Shigella flex...	124	7e-62	193	73	85
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
12	P0ACD4	128	NIFU_ECOLI NifU-like protein OS=Escherichia c...	124	7e-62	193	73	85
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IDA:EcoCyc.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IDA:EcoCyc.
13	P0ACD5	128	NIFU_ECOL6 NifU-like protein OS=Escherichia c...	124	7e-62	193	73	85
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
14	P0ACD6	128	NIFU_ECO57 NifU-like protein OS=Escherichia c...	124	7e-62	193	73	85
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
15	Q57074	126	NIFU_HAEIN NifU-like protein OS=Haemophilus i...	124	1e-61	193	73	89
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
16	Q9D7P6	168	ISCU_MOUSE Iron-sulfur cluster assembly enzym...	135	3e-61	193	70	81	GO:0005739; C:mitochondrion; IDA:MGI.
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
17	Q9H1K1	167	ISCU_HUMAN Iron-sulfur cluster assembly enzym...	134	5e-61	192	71	81	GO:0005829; C:cytosol; IDA:HGNC.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005634; C:nucleus; TAS:HGNC.
									GO:0005506; F:iron ion binding; TAS:UniProtKB.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.::GO:0032947; F:protein complex scaffold; IDA:HGNC.
									GO:0016226; P:iron-sulfur cluster assembly; TAS:UniProtKB.::GO:0009399; P:nitrogen fixation; TAS:UniProtKB.
18	O81433	171	ISU3_ARATH Iron-sulfur cluster assembly prote...	130	1e-60	192	69	82	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; ISS:TAIR.
									GO:0016226; P:iron-sulfur cluster assembly; IGI:TAIR.
19	O51885	128	NIFU_BUCAP NifU-like protein OS=Buchnera aphi...	125	1e-56	180	67	82
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
20	B0YLW7	138	ISU1_TRAHO Iron sulfur cluster assembly prote...	127	6e-56	178	66	81	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
21	Q8SSM2	140	ISU1_ENCCU Iron sulfur cluster assembly prote...	135	7e-55	176	66	79	GO:0032047; C:mitosome; IEA:UniProtKB-KW.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
22	P57658	127	NIFU_BUCAI NifU-like protein OS=(Acyrthosipho...	124	9e-55	175	67	81
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
23	Q9MAB6	163	ISU2_ARATH Iron-sulfur cluster assembly prote...	136	1e-54	176	67	81	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; ISS:TAIR.
									GO:0016226; P:iron-sulfur cluster assembly; IGI:TAIR.
24	Q89A18	126	NIFU_BUCBP NifU-like protein OS=Buchnera aphi...	124	2e-54	174	68	81
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
25	O67045	157	NIFU_AQUAE NifU-like protein OS=Aquifex aeoli...	125	7e-33	120	50	65
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
26	P05340	312	NIFU_AZOVI Nitrogen fixation protein NifU OS=...	124	8e-33	124	48	71
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
27	Q43885	300	NIFU_ANAAZ Nitrogen fixation protein NifU OS=...	125	9e-30	115	48	69
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
28	P20628	300	NIFU_NOSS1 Nitrogen fixation protein NifU OS=...	125	1e-29	115	46	69
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
29	P05343	274	NIFU_KLEPN Nitrogen fixation protein NifU OS=...	124	1e-29	114	44	69
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
30	P23121	309	NIFU_AZOCH Nitrogen fixation protein NifU OS=...	124	1e-29	115	47	68
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
31	Q43909	310	NIFU_AZOBR Nitrogen fixation protein NifU OS=...	126	2e-23	97.8	43	64
									GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.

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