Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL116W
Length:
697
Number of sequences:
5887
Description:
YPL116W HOS3 SGDID:S000006037, Chr XVI from 329606-331699, Genome Release 64-1-1, Verified ORF, "Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) with specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91P32561    433   RPD3_YEAST Histone deacetylase RPD3 OS=Saccha...579.6     33.1     35     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0033698; C:Rpd3L complex; IDA:SGD.::GO:0070210; C:Rpd3L-Expanded complex; IDA:SGD.::GO:0032221; C:Rpd3S complex; IDA:SGD.::GO:0070211; C:Snt2C complex; IDA:SGD.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003713; F:transcription coactivator activity; IMP:SGD.::GO:0003714; F:transcription corepressor activity; IMP:SGD.
GO:0070932; P:histone H3 deacetylation; IMP:SGD.::GO:0070933; P:histone H4 deacetylation; IMP:SGD.::GO:0061188; P:negative regulation of chromatin silencing at rDNA; IMP:SGD.::GO:0061186; P:negative regulation of chromatin silencing at silent mating-type cassette; IMP:SGD.::GO:0031939; P:negative regulation of chromatin silencing at telomere; IDA:SGD.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IMP:SGD.::GO:0051038; P:negative regulation of transcription during meiosis; IMP:SGD.::GO:0016479; P:negative regulation of transcription from RNA polymerase I promoter; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0061408; P:positive regulation of transcription from RNA polymerase II promoter in response to heat stress; IMP:SGD.::GO:0034503; P:protein localization to nucleolar rDNA repeats; IMP:SGD.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:SGD.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IPI:SGD.::GO:0000117; P:regulation of transcription involved in G2/M-phase of mitotic cell cycle; IGI:SGD.::GO:0000115; P:regulation of transcription involved in S phase of mitotic cell cycle; IMP:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IGI:SGD.
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