Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL116W
Length:
697
Number of sequences:
5887
Description:
YPL116W HOS3 SGDID:S000006037, Chr XVI from 329606-331699, Genome Release 64-1-1, Verified ORF, "Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) with specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P56518    576   HDAC1_STRPU Histone deacetylase 1 OS=Strongyl...510.83     36.6     33     53GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
62P56519    488   HDAC2_CHICK Histone deacetylase 2 OS=Gallus g...511.3     35.8     33     53GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
63O59702    405   CLR6_SCHPO Histone deacetylase clr6 OS=Schizo...961.4     35.8     32     47GO:0005829; C:cytosol; IDA:PomBase.::GO:0033698; C:Rpd3L complex; IDA:PomBase.::GO:0070210; C:Rpd3L-Expanded complex; IDA:PomBase.::GO:0032221; C:Rpd3S complex; IDA:PomBase.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006338; P:chromatin remodeling; NAS:PomBase.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IGI:PomBase.::GO:0030261; P:chromosome condensation; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; TAS:PomBase.::GO:0051570; P:regulation of histone H3-K9 methylation; NAS:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
64Q8H0W2    426   HDA9_ARATH Histone deacetylase 9 OS=Arabidops...811.5     35.4     31     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
65P70288    488   HDAC2_MOUSE Histone deacetylase 2 OS=Mus musc...511.5     35.8     33     53GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.::GO:0000792; C:heterochromatin; IDA:MGI.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005657; C:replication fork; IDA:MGI.::GO:0005667; C:transcription factor complex; IPI:MGI.::GO:0017053; C:transcriptional repressor complex; IPI:MGI.
GO:0031490; F:chromatin DNA binding; IDA:MGI.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
GO:0016358; P:dendrite development; IMP:UniProtKB.::GO:0042733; P:embryonic digit morphogenesis; IGI:BHF-UCL.::GO:0009913; P:epidermal cell differentiation; IGI:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; IGI:BHF-UCL.::GO:0061198; P:fungiform papilla formation; IGI:BHF-UCL.::GO:0060789; P:hair follicle placode formation; IGI:BHF-UCL.::GO:0021766; P:hippocampus development; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IGI:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0010977; P:negative regulation of neuron projection development; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0042475; P:odontogenesis of dentin-containing tooth; IGI:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IGI:BHF-UCL.::GO:0048714; P:positive regulation of oligodendrocyte differentiation; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
66Q96DB2    347   HDA11_HUMAN Histone deacetylase 11 OS=Homo sa...461.6     35.4     28     52GO:0000118; C:histone deacetylase complex; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:LIFEdb.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
67Q92769    488   HDAC2_HUMAN Histone deacetylase 2 OS=Homo sap...511.6     35.4     33     53GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB.::GO:0016581; C:NuRD complex; IDA:UniProtKB.::GO:0016580; C:Sin3 complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0006338; P:chromatin remodeling; IC:BHF-UCL.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0042733; P:embryonic digit morphogenesis; ISS:BHF-UCL.::GO:0009913; P:epidermal cell differentiation; ISS:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; ISS:BHF-UCL.::GO:0061198; P:fungiform papilla formation; ISS:BHF-UCL.::GO:0060789; P:hair follicle placode formation; ISS:BHF-UCL.::GO:0006344; P:maintenance of chromatin silencing; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.::GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.::GO:0045347; P:negative regulation of MHC class II biosynthetic process; IC:BHF-UCL.::GO:0010977; P:negative regulation of neuron projection development; ISS:BHF-UCL.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0032967; P:positive regulation of collagen biosynthetic process; IC:BHF-UCL.::GO:0045862; P:positive regulation of proteolysis; IMP:BHF-UCL.::GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
68P56517    480   HDAC1_CHICK Histone deacetylase 1 OS=Gallus g...511.6     35.4     33     53
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
69Q4QQW4    482   HDAC1_RAT Histone deacetylase 1 OS=Rattus nor...481.8     35.4     35     54GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
70O09106    482   HDAC1_MOUSE Histone deacetylase 1 OS=Mus musc...481.8     35.4     35     54GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000792; C:heterochromatin; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0016581; C:NuRD complex; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0003714; F:transcription corepressor activity; IDA:MGI.
GO:0042733; P:embryonic digit morphogenesis; IGI:BHF-UCL.::GO:0007492; P:endoderm development; IDA:MGI.::GO:0009913; P:epidermal cell differentiation; IGI:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; IGI:BHF-UCL.::GO:0061198; P:fungiform papilla formation; IGI:BHF-UCL.::GO:0060789; P:hair follicle placode formation; IGI:BHF-UCL.::GO:0021766; P:hippocampus development; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IGI:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0030182; P:neuron differentiation; IGI:MGI.::GO:0042475; P:odontogenesis of dentin-containing tooth; IGI:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IGI:BHF-UCL.::GO:0048714; P:positive regulation of oligodendrocyte differentiation; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
71Q5RAG0    482   HDAC1_PONAB Histone deacetylase 1 OS=Pongo ab...481.8     35.4     35     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
72Q13547    482   HDAC1_HUMAN Histone deacetylase 1 OS=Homo sap...481.8     35.4     35     54GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016581; C:NuRD complex; IDA:UniProtKB.::GO:0016580; C:Sin3 complex; IDA:BHF-UCL.
GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.::GO:0001047; F:core promoter binding; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0006338; P:chromatin remodeling; IC:BHF-UCL.::GO:0042733; P:embryonic digit morphogenesis; ISS:BHF-UCL.::GO:0009913; P:epidermal cell differentiation; ISS:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; ISS:BHF-UCL.::GO:0061198; P:fungiform papilla formation; ISS:BHF-UCL.::GO:0060789; P:hair follicle placode formation; ISS:BHF-UCL.::GO:0070932; P:histone H3 deacetylation; IDA:BHF-UCL.::GO:0070933; P:histone H4 deacetylation; IDA:BHF-UCL.::GO:0000278; P:mitotic cell cycle; TAS:Reactome.::GO:0043922; P:negative regulation by host of viral transcription; IMP:UniProtKB.::GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:BHF-UCL.::GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
73Q32PJ8    482   HDAC1_BOVIN Histone deacetylase 1 OS=Bos taur...481.9     35.4     35     54
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
74Q9GKU5    347   HDA11_MACFA Histone deacetylase 11 OS=Macaca ...461.9     35     28     52GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
75Q91WA3    347   HDA11_MOUSE Histone deacetylase 11 OS=Mus mus...462.7     34.7     28     52GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
76Q9FML2    471   HDA6_ARATH Histone deacetylase 6 OS=Arabidops...514.4     34.3     31     51GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0016441; P:posttranscriptional gene silencing; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0010431; P:seed maturation; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
77O22446    501   HDA19_ARATH Histone deacetylase 19 OS=Arabido...484.8     33.9     35     54GO:0005634; C:nucleus; IDA:TAIR.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0016573; P:histone acetylation; IDA:TAIR.::GO:0009861; P:jasmonic acid and ethylene-dependent systemic resistance; IMP:TAIR.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:TAIR.::GO:0009405; P:pathogenesis; IMP:TAIR.::GO:2000026; P:regulation of multicellular organismal development; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
78P56521    513   HDA19_MAIZE Probable histone deacetylase 19 O...515     33.9     33     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
79Q803C3    428   HDAC3_DANRE Histone deacetylase 3 OS=Danio re...965.1     33.9     29     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0001525; P:angiogenesis; IMP:ZFIN.::GO:0001889; P:liver development; IMP:ZFIN.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
80Q5RB76    428   HDAC3_PONAB Histone deacetylase 3 OS=Pongo ab...965.2     33.9     29     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
81Q4SFA0    428   HDAC3_TETNG Histone deacetylase 3 OS=nigrovir...965.3     33.9     29     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
82Q94517    521   HDAC1_DROME Histone deacetylase Rpd3 OS=Droso...515.4     33.9     31     51GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; IDA:FlyBase.::GO:0031523; C:Myb complex; IDA:FlyBase.::GO:0016581; C:NuRD complex; IPI:FlyBase.::GO:0005705; C:polytene chromosome interband; IDA:FlyBase.::GO:0016580; C:Sin3 complex; NAS:FlyBase.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003714; F:transcription corepressor activity; IPI:FlyBase.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
GO:0007350; P:blastoderm segmentation; IMP:FlyBase.::GO:0006342; P:chromatin silencing; IMP:FlyBase.::GO:0070983; P:dendrite guidance; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0050771; P:negative regulation of axonogenesis; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0022904; P:respiratory electron transport chain; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IDA:FlyBase.
83P56520    428   HDAC3_CHICK Histone deacetylase 3 OS=Gallus g...965.5     33.9     29     42GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
84P61190    336   ASNA_LACJO Aspartate--ammonia ligase OS=Lacto...265.6     33.5     50     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004812; F:aminoacyl-tRNA ligase activity; IEA:InterPro.::GO:0004071; F:aspartate-ammonia ligase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006529; P:asparagine biosynthetic process; IEA:UniProtKB-KW.::GO:0006418; P:tRNA aminoacylation for protein translation; IEA:InterPro.
85O88895    424   HDAC3_MOUSE Histone deacetylase 3 OS=Mus musc...966.1     33.5     29     42GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
86Q6P6W3    428   HDAC3_RAT Histone deacetylase 3 OS=Rattus nor...966.1     33.5     29     42GO:0000785; C:chromatin; IDA:RGD.::GO:0005737; C:cytoplasm; IDA:RGD.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0070932; P:histone H3 deacetylation; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
87O15379    428   HDAC3_HUMAN Histone deacetylase 3 OS=Homo sap...966.4     33.5     29     42GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.::GO:0046329; P:negative regulation of JNK cascade; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0051225; P:spindle assembly; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
88Q6IRL9    428   HDAC3_XENLA Histone deacetylase 3 OS=Xenopus ...966.7     33.5     29     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
89Q28DV3    428   HDAC3_XENTR Histone deacetylase 3 OS=Xenopus ...967.5     33.5     29     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
90B3LHE1    387   MPS2_YEAS1 Monopolar spindle protein 2 OS=Sac...1018.9     33.1     34     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
91P32561    433   RPD3_YEAST Histone deacetylase RPD3 OS=Saccha...579.6     33.1     35     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0033698; C:Rpd3L complex; IDA:SGD.::GO:0070210; C:Rpd3L-Expanded complex; IDA:SGD.::GO:0032221; C:Rpd3S complex; IDA:SGD.::GO:0070211; C:Snt2C complex; IDA:SGD.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003713; F:transcription coactivator activity; IMP:SGD.::GO:0003714; F:transcription corepressor activity; IMP:SGD.
GO:0070932; P:histone H3 deacetylation; IMP:SGD.::GO:0070933; P:histone H4 deacetylation; IMP:SGD.::GO:0061188; P:negative regulation of chromatin silencing at rDNA; IMP:SGD.::GO:0061186; P:negative regulation of chromatin silencing at silent mating-type cassette; IMP:SGD.::GO:0031939; P:negative regulation of chromatin silencing at telomere; IDA:SGD.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IMP:SGD.::GO:0051038; P:negative regulation of transcription during meiosis; IMP:SGD.::GO:0016479; P:negative regulation of transcription from RNA polymerase I promoter; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0061408; P:positive regulation of transcription from RNA polymerase II promoter in response to heat stress; IMP:SGD.::GO:0034503; P:protein localization to nucleolar rDNA repeats; IMP:SGD.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:SGD.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IPI:SGD.::GO:0000117; P:regulation of transcription involved in G2/M-phase of mitotic cell cycle; IGI:SGD.::GO:0000115; P:regulation of transcription involved in S phase of mitotic cell cycle; IMP:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IGI:SGD.
records
Previous ‹‹ ›› Next Total records: 91 61 - 90
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::