UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YPL116W

Length:

697

Number of sequences:

5887

Description:

YPL116W HOS3 SGDID:S000006037, Chr XVI from 329606-331699, Genome Release 64-1-1, Verified ORF, "Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) with specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	P53973	706	HDA1_YEAST Histone deacetylase HDA1 OS=Saccha...	241	0.00000001	62	27	40	GO:0070823; C:HDA1 complex; IDA:SGD.
									GO:0003682; F:chromatin binding; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
									GO:0031047; P:gene silencing by RNA; IMP:SGD.::GO:0010978; P:gene silencing involved in chronological cell aging; IMP:SGD.::GO:0001308; P:negative regulation of chromatin silencing involved in replicative cell aging; IMP:SGD.::GO:0010621; P:negative regulation of transcription by transcription factor localization; IGI:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0031938; P:regulation of chromatin silencing at telomere; IMP:SGD.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
32	Q613L4	892	HDA4_CAEBR Histone deacetylase 4 OS=Caenorhab...	256	0.00000002	61.6	25	37	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
33	Q569C4	588	HDA10_RAT Histone deacetylase 10 OS=Rattus no...	95	0.00000004	60.1	33	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
									GO:0014003; P:oligodendrocyte development; IEP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
34	Q57955	343	Y535_METJA Uncharacterized protein MJ0535 OS=...	195	0.0000002	57	27	40
									GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
35	P39067	387	ACUC_BACSU Acetoin utilization protein AcuC O...	259	0.0000004	56.6	25	37
									GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
36	Q8GXJ1	552	HDA15_ARATH Histone deacetylase 15 OS=Arabido...	240	0.000001	55.8	26	40	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
37	Q3JUN4	341	APHA_BURP1 Acetylpolyamine aminohydrolase OS=...	62	0.00002	51.2	44	55
									GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
38	Q56195	385	ACUC_STAXY Acetoin utilization protein AcuC O...	260	0.0002	47.8	24	38
									GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
39	P64376	389	ACUC_STAAN Acetoin utilization protein AcuC O...	84	0.0008	45.8	35	49
									GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
40	P64375	389	ACUC_STAAM Acetoin utilization protein AcuC O...	84	0.0008	45.8	35	49
									GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
41	Q8NW34	389	ACUC_STAAW Acetoin utilization protein AcuC O...	84	0.0008	45.8	35	49
									GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
42	Q6G8J2	389	ACUC_STAAS Acetoin utilization protein AcuC O...	84	0.0008	45.8	35	49
									GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
43	Q6GFX3	389	ACUC_STAAR Acetoin utilization protein AcuC O...	84	0.0008	45.8	35	49
									GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
44	Q5HF39	389	ACUC_STAAC Acetoin utilization protein AcuC O...	84	0.0008	45.8	35	49
									GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
45	B1H369	369	HDAC8_XENTR Histone deacetylase 8 OS=Xenopus ...	63	0.001	45.1	38	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46	Q6GPA7	325	HDAC8_XENLA Histone deacetylase 8 OS=Xenopus ...	63	0.001	45.1	38	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
47	P53096	452	HOS2_YEAST Probable histone deacetylase HOS2 ...	66	0.01	42.7	35	58	GO:0070210; C:Rpd3L-Expanded complex; IDA:SGD.::GO:0034967; C:Set3 complex; IDA:SGD.
									GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0045129; F:NAD-independent histone deacetylase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0045835; P:negative regulation of meiosis; IMP:SGD.::GO:0032874; P:positive regulation of stress-activated MAPK cascade; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
48	P28606	300	Y1628_SYNP2 Uncharacterized protein SYNPCC700...	174	0.015	41.6	25	39
									GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
49	Q55BW2	422	HDA12_DICDI Histone deacetylase B OS=Dictyost...	148	0.028	41.2	30	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:dictyBase.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
50	Q944K3	387	HDA2_ARATH Histone deacetylase 2 OS=Arabidops...	45	0.031	40.8	31	53	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
51	B1WC68	377	HDAC8_RAT Histone deacetylase 8 OS=Rattus nor...	63	0.041	40.4	38	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
52	Q8VH37	377	HDAC8_MOUSE Histone deacetylase 8 OS=Mus musc...	63	0.041	40.4	38	52	GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
53	O13298	434	PHD1_SCHPO Histone deacetylase phd1 OS=Schizo...	52	0.078	39.7	37	54	GO:0005829; C:cytosol; IDA:PomBase.::GO:0070210; C:Rpd3L-Expanded complex; IDA:PomBase.::GO:0034967; C:Set3 complex; IDA:PomBase.
									GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
									GO:0006338; P:chromatin remodeling; NAS:PomBase.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0006348; P:chromatin silencing at telomere; IMP:PomBase.::GO:0060303; P:regulation of nucleosome density; IEP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
54	Q0VCB2	377	HDAC8_BOVIN Histone deacetylase 8 OS=Bos taur...	63	0.083	39.7	38	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55	Q9BY41	377	HDAC8_HUMAN Histone deacetylase 8 OS=Homo sap...	63	0.11	39.3	38	49	GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.::GO:0000228; C:nuclear chromosome; TAS:ProtInc.
									GO:0004407; F:histone deacetylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
									GO:0006333; P:chromatin assembly or disassembly; TAS:ProtInc.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
56	Q7SXM0	378	HDAC8_DANRE Histone deacetylase 8 OS=Danio re...	63	0.22	38.1	37	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
57	Q12214	470	HOS1_YEAST Histone deacetylase HOS1 OS=Saccha...	47	0.38	37.7	36	53	GO:0000118; C:histone deacetylase complex; TAS:SGD.
									GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
									GO:0034983; P:peptidyl-lysine deacetylation; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
58	Q09440	507	HDA2_CAEEL Putative histone deacetylase 2 OS=...	83	0.38	37.7	30	45	GO:0000118; C:histone deacetylase complex; ISS:WormBase.
									GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003714; F:transcription corepressor activity; ISS:WormBase.
									GO:0042262; P:DNA protection; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.::GO:0045138; P:tail tip morphogenesis; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
59	O42227	480	HDA1B_XENLA Probable histone deacetylase 1-B ...	51	0.69	36.6	35	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
60	Q91695	480	HDA1A_XENLA Probable histone deacetylase 1-A ...	48	0.69	36.6	38	54	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
61	P56518	576	HDAC1_STRPU Histone deacetylase 1 OS=Strongyl...	51	0.83	36.6	33	53	GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.
									GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.

records

Previous

‹‹

››

Next

Total records:

91

31 - 60