rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q54J98 | 563 | GACX_DICDI Rho GTPase-activating protein gacX... | 165 | 0.00000007 | 60.1 | 29 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 92 | Q91V57 | 459 | CHIN_MOUSE N-chimaerin OS=Mus musculus (Mouse... | 166 | 0.00000009 | 59.7 | 29 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; IMP:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IDA:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB. | 93 | Q9P2N2 | 729 | RHG28_HUMAN Rho GTPase-activating protein 28 ... | 188 | 0.0000001 | 60.1 | 26 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 94 | E9Q6X9 | 672 | RHG40_MOUSE Rho GTPase-activating protein 40 ... | 154 | 0.0000001 | 59.7 | 29 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 95 | A6X8Z5 | 1425 | RHG31_MOUSE Rho GTPase-activating protein 31 ... | 190 | 0.0000001 | 60.1 | 28 | 45 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0030027; C:lamellipodium; IDA:MGI. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IDA:MGI. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI. | 96 | Q811P8 | 2089 | RHG32_MOUSE Rho GTPase-activating protein 32 ... | 180 | 0.0000003 | 58.5 | 26 | 46 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005938; C:cell cortex; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 97 | A7KAX9 | 2087 | RHG32_HUMAN Rho GTPase-activating protein 32 ... | 180 | 0.0000003 | 58.5 | 26 | 46 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 98 | P97393 | 1501 | RHG05_MOUSE Rho GTPase-activating protein 5 O... | 219 | 0.0000004 | 58.5 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030335; P:positive regulation of cell migration; IMP:MGI.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:MGI.::GO:0008361; P:regulation of cell size; IMP:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 99 | Q9Y3L3 | 701 | 3BP1_HUMAN SH3 domain-binding protein 1 OS=Ho... | 189 | 0.0000005 | 57.8 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 100 | Q9WVM1 | 628 | RGAP1_MOUSE Rac GTPase-activating protein 1 O... | 182 | 0.0000005 | 57.4 | 29 | 47 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0097149; C:centralspindlin complex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.::GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB. | | | | | | | | | | GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; ISS:UniProtKB.::GO:0007108; P:cytokinesis, initiation of separation; ISS:UniProtKB.::GO:0009790; P:embryo development; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007405; P:neuroblast proliferation; IEP:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 101 | P52757 | 468 | CHIO_HUMAN Beta-chimaerin OS=Homo sapiens (Hu... | 167 | 0.0000006 | 57 | 28 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 102 | Q7Z6I6 | 1101 | RHG30_HUMAN Rho GTPase-activating protein 30 ... | 189 | 0.0000006 | 57.8 | 30 | 44 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 103 | Q640N3 | 1101 | RHG30_MOUSE Rho GTPase-activating protein 30 ... | 191 | 0.0000007 | 57.4 | 28 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 104 | Q13017 | 1502 | RHG05_HUMAN Rho GTPase-activating protein 5 O... | 206 | 0.0000008 | 57.4 | 25 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 105 | Q12128 | 409 | BAG7_YEAST Rho-GTPase-activating protein BAG7... | 195 | 0.000001 | 56.2 | 27 | 45 | GO:0005622; C:intracellular; TAS:SGD. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IPI:SGD. | 106 | O74360 | 933 | RGA4_SCHPO Probable Rho-type GTPase-activatin... | 165 | 0.000001 | 56.6 | 25 | 52 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0071944; C:cell periphery; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070650; P:actin filament bundle distribution; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0060583; P:regulation of actin cortical patch localization; IMP:PomBase.::GO:0032231; P:regulation of actin filament bundle assembly; IMP:PomBase.::GO:0060305; P:regulation of cell diameter; IMP:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 107 | Q6DE55 | 1107 | HMHA1_XENLA Minor histocompatibility protein ... | 210 | 0.000001 | 56.6 | 27 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 108 | P98171 | 946 | RHG04_HUMAN Rho GTPase-activating protein 4 O... | 197 | 0.000001 | 56.6 | 26 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; TAS:ProtInc.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 109 | O43182 | 974 | RHG06_HUMAN Rho GTPase-activating protein 6 O... | 175 | 0.000001 | 56.2 | 28 | 46 | GO:0005884; C:actin filament; NAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0016004; F:phospholipase activator activity; IDA:BHF-UCL.::GO:0043274; F:phospholipase binding; IPI:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0030041; P:actin filament polymerization; NAS:UniProtKB.::GO:0007202; P:activation of phospholipase C activity; IDA:BHF-UCL.::GO:0051895; P:negative regulation of focal adhesion assembly; IMP:BHF-UCL.::GO:0051497; P:negative regulation of stress fiber assembly; IMP:BHF-UCL.::GO:0007266; P:Rho protein signal transduction; NAS:UniProtKB. | 110 | O54834 | 987 | RHG06_MOUSE Rho GTPase-activating protein 6 O... | 175 | 0.000003 | 55.5 | 27 | 45 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IDA:MGI.::GO:0048041; P:focal adhesion assembly; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro. | 111 | Q5SSM3 | 814 | RHG44_MOUSE Rho GTPase-activating protein 44 ... | 191 | 0.000003 | 55.5 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 112 | Q17R89 | 818 | RHG44_HUMAN Rho GTPase-activating protein 44 ... | 189 | 0.000003 | 55.5 | 26 | 46 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 113 | Q5FWK3 | 439 | RHG01_MOUSE Rho GTPase-activating protein 1 O... | 164 | 0.000003 | 54.7 | 24 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI. | | | | | | | | | | GO:0030675; F:Rac GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 114 | Q86IG9 | 566 | GACH_DICDI Rho GTPase-activating protein gacH... | 167 | 0.000003 | 54.7 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 115 | Q8K0Q5 | 663 | RHG18_MOUSE Rho GTPase-activating protein 18 ... | 152 | 0.000004 | 54.7 | 28 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 116 | P38339 | 666 | RGD1_YEAST RHO GTPase-activating protein RGD1... | 232 | 0.000004 | 54.7 | 26 | 46 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005933; C:cellular bud; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IMP:SGD.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IMP:SGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:SGD.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IMP:SGD.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0007231; P:osmosensory signaling pathway; IGI:SGD.::GO:0001101; P:response to acid; IMP:SGD. | 117 | Q07960 | 439 | RHG01_HUMAN Rho GTPase-activating protein 1 O... | 172 | 0.000006 | 53.9 | 26 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 118 | Q9VDS5 | 740 | RG92B_DROME Rho GTPase-activating protein 92B... | 189 | 0.000006 | 54.3 | 26 | 46 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 119 | Q54XT6 | 783 | GACR_DICDI Rho GTPase-activating protein gacR... | 196 | 0.000007 | 53.9 | 24 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 120 | Q6Y5D8 | 786 | RHG10_MOUSE Rho GTPase-activating protein 10 ... | 165 | 0.000008 | 53.9 | 28 | 47 | GO:0005829; C:cytosol; IMP:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IPI:MGI.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 121 | Q9DBZ9 | 737 | SYDE1_MOUSE Rho GTPase-activating protein SYD... | 189 | 0.000008 | 53.9 | 24 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. |