Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL115C
Length:
1128
Number of sequences:
5887
Description:
YPL115C BEM3 SGDID:S000006036, Chr XVI from 335486-332100, Genome Release 64-1-1, reverse complement, Verified ORF, "Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31A6QNS3    859   ABR_BOVIN Active breakpoint cluster region-re...1910.0000000000007     77     30     47
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
32Q6ZUM4    889   RHG27_HUMAN Rho GTPase-activating protein 27 ...2070.0000000000009     76.6     26     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; ISS:HGNC.::GO:0017124; F:SH3 domain binding; ISS:HGNC.
GO:0043089; P:positive regulation of Cdc42 GTPase activity; ISS:HGNC.::GO:0006898; P:receptor-mediated endocytosis; ISS:HGNC.::GO:0007165; P:signal transduction; IEA:InterPro.
33Q54FG5    873   GACJJ_DICDI Rho GTPase-activating protein gac...1920.000000000002     75.5     30     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
34Q9V9S7    1866   SYDE_DROME Rho GTPase-activating protein 100F...2020.00000000002     72.8     29     49GO:0005622; C:intracellular; IEA:InterPro.::GO:0048786; C:presynaptic active zone; IDA:FlyBase.
GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.
GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0048789; P:cytoskeletal matrix organization at active zone; IMP:FlyBase.::GO:0048790; P:maintenance of presynaptic active zone structure; IMP:FlyBase.::GO:0007165; P:signal transduction; IEA:InterPro.
35Q69ZH9    1483   RHG23_MOUSE Rho GTPase-activating protein 23 ...1880.00000000003     72     29     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
36Q7Z6B7    1085   SRGP1_HUMAN SLIT-ROBO Rho GTPase-activating p...2010.00000000004     71.2     30     52GO:0005829; C:cytosol; TAS:Reactome.
GO:0007411; P:axon guidance; TAS:Reactome.
37Q9P227    1491   RHG23_HUMAN Rho GTPase-activating protein 23 ...1890.00000000005     71.2     29     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
38Q8BYW1    648   RHG25_MOUSE Rho GTPase-activating protein 25 ...2200.00000000006     70.5     27     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
39Q5TG30    622   RHG40_HUMAN Rho GTPase-activating protein 40 ...2430.00000000006     70.1     28     44GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
40A4IF90    471   RHG15_BOVIN Rho GTPase-activating protein 15 ...1910.00000000009     69.3     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
41Q54YV1    817   GACII_DICDI Rho GTPase-activating protein gac...1860.0000000001     69.3     26     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
42O43295    1099   SRGP3_HUMAN SLIT-ROBO Rho GTPase-activating p...1950.0000000001     69.3     29     48GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
43Q15311    655   RBP1_HUMAN RalA-binding protein 1 OS=Homo sap...1890.0000000002     68.9     30     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IDA:UniProtKB.
GO:0043492; F:ATPase activity, coupled to movement of substances; IDA:UniProtKB.::GO:0030675; F:Rac GTPase activator activity; IDA:UniProtKB.::GO:0048365; F:Rac GTPase binding; IPI:UniProtKB.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB.
GO:0006935; P:chemotaxis; TAS:ProtInc.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IPI:UniProtKB.::GO:0006810; P:transport; IDA:UniProtKB.
44Q5ZMM3    475   RHG15_CHICK Rho GTPase-activating protein 15 ...2290.0000000002     68.2     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
45O94988    1023   FA13A_HUMAN Protein FAM13A OS=Homo sapiens (H...1920.0000000002     68.9     28     53GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
46Q53QZ3    475   RHG15_HUMAN Rho GTPase-activating protein 15 ...2270.0000000002     68.2     29     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI.
GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
47Q54C77    1186   Y3184_DICDI Probable inactive serine/threonin...1890.0000000003     68.6     31     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
48O75044    1071   FNBP2_HUMAN SLIT-ROBO Rho GTPase-activating p...1640.0000000003     68.2     28     51GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
49Q54G18    1115   GACW_DICDI Rho GTPase-activating protein gacW...1650.0000000004     68.2     30     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
50P81128    1513   RHG35_RAT Rho GTPase-activating protein 35 OS...1710.0000000005     67.8     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
51Q62796    647   RBP1_RAT RalA-binding protein 1 OS=Rattus nor...1880.0000000005     67.4     29     46GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IMP:RGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007052; P:mitotic spindle organization; IDA:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IPI:RGD.
52Q559A0    1164   GACU_DICDI Rho GTPase-activating protein gacU...1910.0000000005     67.8     31     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
53Q9VTU3    476   RG68F_DROME Rho GTPase-activating protein 68F...1640.0000000006     66.6     32     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0005100; F:Rho GTPase activator activity; IDA:FlyBase.
GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007370; P:ventral furrow formation; IMP:FlyBase.
54P34288    1605   PAC1_CAEEL GTPase-activating protein pac-1 OS...1730.0000000007     67.4     29     51GO:0030054; C:cell junction; IDA:WormBase.::GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.
GO:0008105; P:asymmetric protein localization; IMP:WormBase.::GO:0010470; P:regulation of gastrulation; IMP:WormBase.::GO:0007266; P:Rho protein signal transduction; IDA:UniProtKB.
55P42331    645   RHG25_HUMAN Rho GTPase-activating protein 25 ...2160.0000000007     67     26     45GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
56Q91Z69    1062   SRGP1_MOUSE SLIT-ROBO Rho GTPase-activating p...1770.0000000008     67     31     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0017048; F:Rho GTPase binding; IDA:MGI.
GO:0016477; P:cell migration; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI.
57Q9VIS1    1843   CDGAP_DROME GTPase-activating protein CdGAPr ...1880.0000000008     67     28     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0031290; P:retinal ganglion cell axon guidance; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
58Q62172    648   RBP1_MOUSE RalA-binding protein 1 OS=Mus musc...1880.0000000008     66.6     29     46GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; ISS:UniProtKB.
GO:0030675; F:Rac GTPase activator activity; IDA:UniProtKB.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB.
GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.
59Q86L99    1523   GACHH_DICDI Rho GTPase-activating protein gac...1980.000000001     66.2     29     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
60P83509    1500   RHG35_CANFA Rho GTPase-activating protein 35 ...1710.000000001     66.2     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042478; P:regulation of eye photoreceptor cell development; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
61Q9NRY4    1513   RHG35_HUMAN Rho GTPase-activating protein 35 ...1710.000000002     66.2     29     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; TAS:Reactome.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; TAS:ProtInc.
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