Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL091W
Length:
483
Number of sequences:
5887
Description:
YPL091W GLR1 SGDID:S000006012, Chr XVI from 375502-376953, Genome Release 64-1-1, Verified ORF, "Cytosolic and mitochondrial glutathione oxidoreductase, converts oxidized glutathione to reduced glutathione; mitochondrial but not cytosolic form has a role in resistance to hyperoxia"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P48642    496   GSHRC_ORYSJ Glutathione reductase, cytosolic ...4911e-90     291     35     54
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
32Q9JLT4    524   TRXR2_MOUSE Thioredoxin reductase 2, mitochon...4807e-85     277     35     55GO:0005739; C:mitochondrion; IDA:UniProtKB.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004791; F:thioredoxin-disulfide reductase activity; ISS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0007507; P:heart development; IMP:MGI.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB.
33Q9N2I8    511   TRXR2_BOVIN Thioredoxin reductase 2, mitochon...4792e-83     273     35     54GO:0005739; C:mitochondrion; IDA:UniProtKB.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB.
34Q9Z0J5    526   TRXR2_RAT Thioredoxin reductase 2, mitochondr...4812e-83     273     35     55GO:0030424; C:axon; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:RGD.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0042493; P:response to drug; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; TAS:RGD.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB.::GO:0010269; P:response to selenium ion; IEP:RGD.
35P30635    503   GSHR_CAEEL Probable glutathione reductase 2 O...4908e-82     268     33     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:WormBase.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
36B9A1H3    495   TRXR1_EMIHU Thioredoxin reductase SEP1 OS=Emi...4912e-79     262     35     55GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
37P13110    492   TYTR_TRYCO Trypanothione reductase OS=Trypano...4892e-79     262     34     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
38Q9NNW7    524   TRXR2_HUMAN Thioredoxin reductase 2, mitochon...4682e-77     258     34     54GO:0005739; C:mitochondrion; IDA:UniProtKB.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; ISS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB.
39Q25861    541   TRXR_PLAF5 Thioredoxin reductase OS=Plasmodiu...5021e-76     256     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
40P91938    596   TRXR1_DROME Thioredoxin reductase 1, mitochon...4911e-76     257     34     55GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005739; C:mitochondrion; IDA:UniProtKB.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IMP:FlyBase.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:FlyBase.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB.
GO:0045454; P:cell redox homeostasis; IMP:UniProtKB.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0001666; P:response to hypoxia; IMP:FlyBase.
41P61076    617   TRXR2_PLAF7 Thioredoxin reductase 2 OS=Plasmo...5015e-76     256     34     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
42Q9VNT5    516   TRXR2_DROME Thioredoxin reductase 2, mitochon...5084e-75     251     33     53GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:FlyBase.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
43O62768    499   TRXR1_BOVIN Thioredoxin reductase 1, cytoplas...4656e-75     250     35     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
44P39051    492   TYTR_TRYBB Trypanothione reductase OS=Trypano...4891e-74     249     35     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
45O89049    499   TRXR1_RAT Thioredoxin reductase 1, cytoplasmi...4409e-73     244     35     56GO:0005829; C:cytosol; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0045340; F:mercury ion binding; IDA:RGD.::GO:0016174; F:NAD(P)H oxidase activity; IDA:RGD.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0033797; F:selenate reductase activity; IDA:RGD.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:RGD.
GO:0042537; P:benzene-containing compound metabolic process; IDA:RGD.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0071280; P:cellular response to copper ion; IEP:RGD.::GO:0071455; P:cellular response to hyperoxia; IEP:RGD.::GO:0006749; P:glutathione metabolic process; IEP:RGD.::GO:0070276; P:halogen metabolic process; IEP:RGD.::GO:0042744; P:hydrogen peroxide catabolic process; IMP:RGD.::GO:0042191; P:methylmercury metabolic process; IEP:RGD.::GO:0070995; P:NADPH oxidation; IDA:RGD.::GO:0001890; P:placenta development; IEP:RGD.::GO:0010942; P:positive regulation of cell death; IMP:RGD.::GO:0051262; P:protein tetramerization; IDA:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0010269; P:response to selenium ion; IEP:RGD.::GO:0016259; P:selenocysteine metabolic process; IMP:RGD.
46Q5NVA2    499   TRXR1_PONAB Thioredoxin reductase 1, cytoplas...4651e-72     244     34     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
47P39050    491   TYTR_LEIDO Trypanothione reductase OS=Leishma...4851e-72     244     33     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
48P28593    492   TYTR_TRYCR Trypanothione reductase OS=Trypano...4839e-72     242     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
49Q9JMH6    613   TRXR1_MOUSE Thioredoxin reductase 1, cytoplas...4409e-72     244     35     56GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:MGI.
GO:0008283; P:cell proliferation; IMP:MGI.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0001707; P:mesoderm formation; IMP:MGI.
50Q9MYY8    499   TRXR1_PIG Thioredoxin reductase 1, cytoplasmi...4391e-71     241     35     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
51Q16881    649   TRXR1_HUMAN Thioredoxin reductase 1, cytoplas...4652e-71     244     34     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; EXP:Reactome.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.::GO:0007165; P:signal transduction; NAS:ProtInc.::GO:0006810; P:transport; IEA:UniProtKB-KW.
52Q99MD6    697   TRXR3_MOUSE Thioredoxin reductase 3 OS=Mus mu...4663e-69     240     33     55GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:MGI.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006749; P:glutathione metabolic process; IDA:MGI.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
53Q17745    667   TRXR1_CAEEL Thioredoxin reductase 1 OS=Caenor...5096e-69     238     33     53GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0015036; F:disulfide oxidoreductase activity; NAS:UniProtKB.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; ISS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
54P39040    491   TYTR_CRIFA Trypanothione reductase OS=Crithid...4892e-68     233     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
55Q86VQ6    682   TRXR3_HUMAN Thioredoxin reductase 3 OS=Homo s...4657e-64     224     31     53GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; NAS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; NAS:UniProtKB.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
56Q9PJI3    465   DLDH_CHLMU Dihydrolipoyl dehydrogenase OS=Chl...4652e-58     205     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:InterPro.
57P16171    631   MERA_BACCE Mercuric reductase OS=Bacillus cer...4635e-58     207     31     51GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro.
58P21880    470   DLDH1_BACSU Dihydrolipoyl dehydrogenase OS=Ba...4632e-57     203     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
59O84561    465   DLDH_CHLTR Dihydrolipoyl dehydrogenase OS=Chl...4652e-57     202     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
60Q9Z773    461   DLDH_CHLPN Dihydrolipoyl dehydrogenase OS=Chl...4634e-57     202     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
61P85207    461   DLDH_THESS Dihydrolipoyl dehydrogenase OS=The...4665e-57     201     31     50GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
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