Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL087W
Length:
317
Number of sequences:
5887
Description:
YPL087W YDC1 SGDID:S000006008, Chr XVI from 383455-384408, Genome Release 64-1-1, Verified ORF, "Alkaline dihydroceramidase, involved in sphingolipid metabolism; preferentially hydrolyzes dihydroceramide to a free fatty acid and dihydrosphingosine; has a minor reverse activity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q02896    317   YDC1_YEAST Alkaline ceramidase YDC1 OS=Saccha...3170     647     100     100GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0071633; F:dihydroceramidase activity; IDA:SGD.
GO:0046514; P:ceramide catabolic process; IMP:SGD.
2P38298    316   YPC1_YEAST Alkaline ceramidase YPC1 OS=Saccha...3157e-120     354     53     72GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0070774; F:phytoceramidase activity; IMP:SGD.::GO:0050291; F:sphingosine N-acyltransferase activity; IMP:SGD.
GO:0046514; P:ceramide catabolic process; IMP:SGD.
3Q9D099    267   ACER3_MOUSE Alkaline ceramidase 3 OS=Mus musc...2588e-42     151     34     55
GO:0006672; P:ceramide metabolic process; IEA:InterPro.
4Q9NUN7    267   ACER3_HUMAN Alkaline ceramidase 3 OS=Homo sap...2602e-41     150     35     56GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0030173; C:integral to Golgi membrane; IDA:UniProtKB.
GO:0070774; F:phytoceramidase activity; IDA:UniProtKB.
GO:0006672; P:ceramide metabolic process; IEA:InterPro.::GO:0071602; P:phytosphingosine biosynthetic process; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0046512; P:sphingosine biosynthetic process; IDA:UniProtKB.
5Q6TMJ1    288   DCD3A_DICDI Putative alkaline ceramidase dcd3...2782e-23     101     29     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; ISS:dictyBase.
GO:0046514; P:ceramide catabolic process; ISS:dictyBase.::GO:0006669; P:sphinganine-1-phosphate biosynthetic process; ISS:dictyBase.
6Q55DQ0    285   DCD3B_DICDI Putative alkaline ceramidase dcd3...2789e-18     84.7     29     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; ISS:dictyBase.
GO:0046514; P:ceramide catabolic process; ISS:dictyBase.::GO:0006669; P:sphinganine-1-phosphate biosynthetic process; ISS:dictyBase.
7Q5QJU3    275   ACER2_HUMAN Alkaline ceramidase 2 OS=Homo sap...2460.0000000003     63.5     26     42GO:0030173; C:integral to Golgi membrane; IDA:UniProtKB.
GO:0017040; F:ceramidase activity; IDA:UniProtKB.
GO:0006672; P:ceramide metabolic process; IEA:InterPro.::GO:0033629; P:negative regulation of cell adhesion mediated by integrin; IDA:UniProtKB.::GO:0001953; P:negative regulation of cell-matrix adhesion; IDA:UniProtKB.::GO:0090285; P:negative regulation of protein glycosylation in Golgi; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0032526; P:response to retinoic acid; IDA:UniProtKB.::GO:0046512; P:sphingosine biosynthetic process; IDA:UniProtKB.
8Q8VD53    275   ACER2_MOUSE Alkaline ceramidase 2 OS=Mus musc...2490.000000002     60.8     25     39
GO:0017040; F:ceramidase activity; IEA:EC.
GO:0006672; P:ceramide metabolic process; IEA:InterPro.
9Q8R4X1    273   ACER1_MOUSE Alkaline ceramidase 1 OS=Mus musc...2470.00000001     58.5     26     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; IDA:MGI.
GO:0046514; P:ceramide catabolic process; IDA:MGI.::GO:0019216; P:regulation of lipid metabolic process; IDA:MGI.
10Q9VIP7    283   ACASE_DROME Alkaline ceramidase OS=Drosophila...2490.00000008     56.2     24     43GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; ISS:UniProtKB.
GO:0007420; P:brain development; IMP:FlyBase.::GO:0046514; P:ceramide catabolic process; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.
11Q568I2    266   ACER1_DANRE Alkaline ceramidase 1 OS=Danio re...2430.0000001     55.5     28     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; IEA:EC.
GO:0006672; P:ceramide metabolic process; IEA:InterPro.
12Q8TDN7    264   ACER1_HUMAN Alkaline ceramidase 1 OS=Homo sap...2340.0000002     55.1     27     45GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; IEA:EC.
GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
13Q60WT2    272   ACASE_CAEBR Alkaline ceramidase OS=Caenorhabd...2640.0001     46.6     22     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; IEA:EC.
GO:0006672; P:ceramide metabolic process; IEA:InterPro.
14O45145    272   ACASE_CAEEL Alkaline ceramidase OS=Caenorhabd...2390.0004     44.7     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0017040; F:ceramidase activity; IEA:EC.
GO:0006672; P:ceramide metabolic process; IEA:InterPro.
15Q17574    682   MTRR_CAEEL Putative methionine synthase reduc...530.081     38.5     38     55
GO:0030586; F:[methionine synthase reductase activity; IEA:EC.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.]
16O51750    506   MURJ_BORBU Protein MurJ homolog OS=4680). GN=...2056.3     32.3     21     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
records
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