UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YPL086C

Length:

557

Number of sequences:

5887

Description:

YPL086C ELP3 SGDID:S000006007, Chr XVI from 386446-384773, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; exhibits histone acetyltransferase activity that is directed to histones H3 and H4; disruption confers resistance to K. lactis zymotoxin"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q02908	557	ELP3_YEAST Elongator complex protein 3 OS=Sac...	557	0	1157	100	100	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0033588; C:Elongator holoenzyme complex; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0004402; F:histone acetyltransferase activity; IDA:SGD.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0002098; P:tRNA wobble uridine modification; IMP:SGD.
2	O14023	544	ELP3_SCHPO Probable elongator complex protein...	534	0	892	79	89	GO:0000785; C:chromatin; NAS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0033588; C:Elongator holoenzyme complex; ISS:PomBase.
									GO:0004402; F:histone acetyltransferase activity; ISS:PomBase.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006400; P:tRNA modification; ISS:PomBase.
3	Q5RIC0	548	ELP3_DANRE Elongator complex protein 3 OS=Dan...	549	0	868	75	86	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0008023; C:transcription elongation factor complex; ISS:UniProtKB.
									GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008607; F:phosphorylase kinase regulator activity; ISS:UniProtKB.
									GO:0007409; P:axonogenesis; IMP:ZFIN.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4	Q5ZHS1	546	ELP3_CHICK Elongator complex protein 3 OS=Gal...	547	0	867	75	87	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0008023; C:transcription elongation factor complex; ISS:UniProtKB.
									GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008607; F:phosphorylase kinase regulator activity; ISS:UniProtKB.
									GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5	Q5HZM6	549	ELP3_XENLA Elongator complex protein 3 OS=Xen...	540	0	865	76	87	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0008023; C:transcription elongation factor complex; ISS:UniProtKB.
									GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008607; F:phosphorylase kinase regulator activity; ISS:UniProtKB.
									GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6	Q6NVL5	549	ELP3_XENTR Elongator complex protein 3 OS=Xen...	552	0	844	75	86	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0008023; C:transcription elongation factor complex; ISS:UniProtKB.
									GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008607; F:phosphorylase kinase regulator activity; ISS:UniProtKB.
									GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7	Q9H9T3	547	ELP3_HUMAN Elongator complex protein 3 OS=Hom...	546	0	835	75	86	GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IDA:HGNC.::GO:0005730; C:nucleolus; IDA:HGNC.::GO:0008023; C:transcription elongation factor complex; IDA:UniProtKB.
									GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008607; F:phosphorylase kinase regulator activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:HGNC.
8	Q2KJ61	547	ELP3_BOVIN Elongator complex protein 3 OS=Bos...	546	0	832	74	86	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0008023; C:transcription elongation factor complex; ISS:UniProtKB.
									GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008607; F:phosphorylase kinase regulator activity; ISS:UniProtKB.
									GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
9	Q9CZX0	547	ELP3_MOUSE Elongator complex protein 3 OS=Mus...	549	0	826	73	85	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0008023; C:transcription elongation factor complex; ISS:UniProtKB.
									GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008607; F:phosphorylase kinase regulator activity; ISS:UniProtKB.
									GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
10	Q9VQZ6	552	ELP3_DROME Probable elongator complex protein...	549	0	825	74	85	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0008023; C:transcription elongation factor complex; ISS:UniProtKB.
									GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008607; F:phosphorylase kinase regulator activity; ISS:UniProtKB.
									GO:0007626; P:locomotory behavior; IMP:FlyBase.::GO:0045494; P:photoreceptor cell maintenance; IMP:FlyBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030431; P:sleep; IMP:FlyBase.::GO:0051124; P:synaptic growth at neuromuscular junction; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11	Q1ZXC6	559	ELP3_DICDI Probable elongator complex protein...	535	0	800	72	86	GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; ISS:dictyBase.::GO:0008023; C:transcription elongation factor complex; ISS:dictyBase.
									GO:0004402; F:histone acetyltransferase activity; ISS:dictyBase.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:dictyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12	Q93ZR1	565	ELP3_ARATH Elongator complex protein 3 OS=Ara...	540	0	796	69	82	GO:0005829; C:cytosol; IDA:TAIR.::GO:0033588; C:Elongator holoenzyme complex; IDA:UniProtKB.::GO:0005719; C:nuclear euchromatin; IDA:UniProtKB.
									GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009734; P:auxin mediated signaling pathway; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; IMP:TAIR.::GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0035265; P:organ growth; IMP:TAIR.::GO:0010928; P:regulation of auxin mediated signaling pathway; IMP:UniProtKB.::GO:2000025; P:regulation of leaf formation; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0010084; P:specification of organ axis polarity; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0002098; P:tRNA wobble uridine modification; IMP:UniProtKB.
13	Q23651	547	ELP3_CAEEL Probable elongator complex protein...	515	0	792	75	86	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0008023; C:transcription elongation factor complex; ISS:UniProtKB.
									GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008607; F:phosphorylase kinase regulator activity; ISS:UniProtKB.
									GO:0048598; P:embryonic morphogenesis; IGI:WormBase.::GO:0008355; P:olfactory learning; IMP:WormBase.::GO:0048599; P:oocyte development; IGI:WormBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IGI:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006412; P:translation; IMP:WormBase.::GO:0002098; P:tRNA wobble uridine modification; IMP:WormBase.::GO:0040025; P:vulval development; IGI:WormBase.
14	Q7X7L3	573	ELP3_ORYSJ Elongator complex protein 3 OS=Ory...	538	0	791	69	83	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15	Q60LW7	548	ELP3_CAEBR Probable elongator complex protein...	515	0	790	74	86	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0008023; C:transcription elongation factor complex; ISS:UniProtKB.
									GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008607; F:phosphorylase kinase regulator activity; ISS:UniProtKB.
									GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16	Q58536	541	Y1136_METJA Uncharacterized protein MJ1136 OS...	497	1e-148	445	46	64
									GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.::GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
17	Q57910	322	Y486_METJA Uncharacterized protein MJ0486 OS=...	315	0.000000000000003	80.5	23	40
									GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
18	O35008	322	YTQA_BACSU Putative protein ytqA OS=Bacillus ...	191	0.00000000003	68.6	28	48
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
19	P0ADW6	309	YHCC_ECOLI Uncharacterized protein yhcC OS=Es...	174	0.0000000003	65.5	24	45
									GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
20	P0ADW7	309	YHCC_ECO57 Uncharacterized protein yhcC OS=Es...	174	0.0000000003	65.5	24	45
									GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
21	A4IGH2	444	RSAD1_DANRE Radical S-adenosyl methionine dom...	127	0.002	44.3	28	45	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004109; F:coproporphyrinogen oxidase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
22	Q58882	426	Y1487_METJA Uncharacterized methyltransferase...	81	0.027	40.8	35	49
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0031419; F:cobalamin binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
23	Q9HA92	442	RSAD1_HUMAN Radical S-adenosyl methionine dom...	170	0.042	40	25	39	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004109; F:coproporphyrinogen oxidase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
24	P54304	379	HEMN_BACSU Oxygen-independent coproporphyrino...	122	0.05	40	25	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0051989; F:coproporphyrinogen dehydrogenase activity; IEA:EC.::GO:0004109; F:coproporphyrinogen oxidase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
25	Q5SUV1	442	RSAD1_MOUSE Radical S-adenosyl methionine dom...	113	0.36	37.4	27	43	GO:0005739; C:mitochondrion; IDA:MGI.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004109; F:coproporphyrinogen oxidase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
26	A6Q5D0	322	MOAA_NITSB Molybdenum cofactor biosynthesis p...	155	0.44	36.6	25	43	GO:0019008; C:molybdopterin synthase complex; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
27	Q796V8	501	HEMZ_BACSU Oxygen-independent coproporphyrino...	79	0.45	37	30	48
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0051989; F:coproporphyrinogen dehydrogenase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
28	P43899	383	Y463_HAEIN Oxygen-independent coproporphyrino...	92	0.59	36.6	23	42	GO:0005737; C:cytoplasm; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004109; F:coproporphyrinogen oxidase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
29	B1XIZ3	213	NUSB_SYNP2 N utilization substance protein B ...	152	0.92	35.4	22	39
									GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006353; P:transcription termination, DNA-dependent; IEA:UniProtKB-KW.
30	O67886	456	HEMN_AQUAE Oxygen-independent coproporphyrino...	96	1.1	35.8	26	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0051989; F:coproporphyrinogen dehydrogenase activity; IEA:EC.::GO:0004109; F:coproporphyrinogen oxidase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
31	Q10351	554	PIGS_SCHPO GPI transamidase component PIG-S h...	96	2.4	34.7	26	45	GO:0042765; C:GPI-anchor transamidase complex; ISS:PomBase.
									GO:0016255; P:attachment of GPI anchor to protein; ISS:PomBase.

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