UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YPL059W

Length:

150

Number of sequences:

5887

Description:

YPL059W GRX5 SGDID:S000005980, Chr XVI from 444579-445031, Genome Release 64-1-1, Verified ORF, "Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; mitochondrial matrix protein involved in the synthesis/assembly of iron-sulfur centers; monothiol glutaredoxin subfamily member along with Grx3p and Grx4p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	P32642	244	GLRX4_YEAST Monothiol glutaredoxin-4 OS=Sacch...	79	4e-23	95.9	49	73	GO:0005634; C:nucleus; IGI:SGD.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0030036; P:actin cytoskeleton organization; IMP:SGD.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006879; P:cellular iron ion homeostasis; IGI:SGD.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.
32	Q9CMN5	109	GLRX4_PASMU Glutaredoxin-4 OS=Pasteurella mul...	111	7e-23	92	38	59	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
33	Q9CQM9	337	GLRX3_MOUSE Glutaredoxin-3 OS=Mus musculus (M...	90	2e-20	89.4	43	68	GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:UniProtKB.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0010614; P:negative regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0002026; P:regulation of the force of heart contraction; IMP:UniProtKB.
34	Q48833	89	GLRXA_LEGPH Probable monothiol glutaredoxin g...	91	1e-22	90.9	46	67
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
35	O76003	335	GLRX3_HUMAN Glutaredoxin-3 OS=Homo sapiens (H...	89	1e-20	89.7	44	67	GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0010614; P:negative regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0002026; P:regulation of the force of heart contraction; ISS:UniProtKB.
36	O30824	107	GLRX4_HAEDU Glutaredoxin-4 OS=Haemophilus duc...	100	2e-22	91.3	43	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
37	Q58DA7	334	GLRX3_BOVIN Glutaredoxin-3 OS=Bos taurus (Bov...	90	4e-21	90.9	43	68	GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0010614; P:negative regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0002026; P:regulation of the force of heart contraction; ISS:UniProtKB.
38	Q2QX01	285	GRS12_ORYSJ Monothiol glutaredoxin-S12, chlor...	112	3e-22	94.4	39	63
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
39	Q9JLZ1	337	GLRX3_RAT Glutaredoxin-3 OS=Rattus norvegicus...	90	2e-20	89.4	43	68	GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0005080; F:protein kinase C binding; IDA:RGD.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
40	P57284	108	GLRX4_BUCAI Glutaredoxin-4 OS=(Acyrthosiphon ...	101	1e-21	89	42	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
41	Q4QLD2	107	GLRX4_HAEI8 Glutaredoxin-4 OS=Haemophilus inf...	107	2e-21	88.6	39	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
42	P45085	107	GLRX4_HAEIN Glutaredoxin-4 OS=Haemophilus inf...	107	5e-21	87.4	38	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
43	Q8K9V6	107	GLRX4_BUCAP Glutaredoxin-4 OS=Buchnera aphidi...	99	1e-19	83.6	38	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
44	Q0JM76	185	GRXS4_ORYSJ Monothiol glutaredoxin-S4, mitoch...	98	2e-19	84.7	37	62	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
45	Q0JQ97	185	GRXS1_ORYSJ Monothiol glutaredoxin-S1, mitoch...	94	2e-18	82.4	39	63	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
46	Q19297	146	YZ73_CAEEL Uncharacterized monothiol glutared...	81	0.00000008	51.6	33	58
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
47	Q9SA68	102	GRXS1_ARATH Monothiol glutaredoxin-S1 OS=Arab...	102	0.0000001	50.4	26	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
48	Q8L8T2	125	GRXC1_ARATH Glutaredoxin-C1 OS=Arabidopsis th...	129	0.0000005	48.9	29	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
49	Q54GP8	100	GLRX_DICDI Glutaredoxin OS=Dictyostelium disc...	50	0.0000008	48.1	40	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0043295; F:glutathione binding; IDA:dictyBase.::GO:0004364; F:glutathione transferase activity; IDA:dictyBase.::GO:0050661; F:NADP binding; IDA:dictyBase.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IMP:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006979; P:response to oxidative stress; IMP:dictyBase.
50	P12309	106	GLRX1_PIG Glutaredoxin-1 OS=Sus scrofa (Pig)....	107	0.000001	47.4	30	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
51	Q9ZR41	108	GLRX_SOLLC Glutaredoxin OS=Solanum lycopersic...	101	0.000003	46.6	31	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
52	Q9QUH0	107	GLRX1_MOUSE Glutaredoxin-1 OS=Mus musculus (M...	103	0.000006	45.8	29	53	GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0019153; F:protein-disulfide reductase (glutathione) activity; TAS:MGI.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
53	Q9FNE2	111	GRXC2_ARATH Glutaredoxin-C2 OS=Arabidopsis th...	101	0.000009	45.4	29	50	GO:0005829; C:cytosol; IDA:TAIR.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
54	Q86VQ6	682	TRXR3_HUMAN Thioredoxin reductase 3 OS=Homo s...	103	0.00001	47.4	30	48	GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; NAS:UniProtKB.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; NAS:UniProtKB.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
55	Q9ESH6	107	GLRX1_RAT Glutaredoxin-1 OS=Rattus norvegicus...	110	0.00001	44.7	27	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
56	Q9LIF1	102	GRS10_ARATH Monothiol glutaredoxin-S10 OS=Ara...	93	0.00002	44.3	30	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
57	Q9HU55	84	GLRX_PSEAE Glutaredoxin OS=12228). GN=grx Ord...	88	0.00003	43.5	32	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
58	Q0J3L4	164	GRS10_ORYSJ Monothiol glutaredoxin-S10 OS=Ory...	100	0.00003	45.1	25	47
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
59	P55142	112	GRXC6_ORYSJ Glutaredoxin-C6 OS=Oryza sativa s...	104	0.00003	43.9	30	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
60	P12864	106	GLRX1_RABIT Glutaredoxin-1 OS=Oryctolagus cun...	107	0.00003	43.5	28	50
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
61	P10575	106	GLRX1_BOVIN Glutaredoxin-1 OS=Bos taurus (Bov...	110	0.00004	43.5	30	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.

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