UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YPL059W

Length:

150

Number of sequences:

5887

Description:

YPL059W GRX5 SGDID:S000005980, Chr XVI from 444579-445031, Genome Release 64-1-1, Verified ORF, "Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; mitochondrial matrix protein involved in the synthesis/assembly of iron-sulfur centers; monothiol glutaredoxin subfamily member along with Grx3p and Grx4p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q02784	150	GLRX5_YEAST Monothiol glutaredoxin-5, mitocho...	150	3e-106	306	100	100	GO:0005759; C:mitochondrial matrix; IDA:SGD.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.::GO:0016226; P:iron-sulfur cluster assembly; TAS:SGD.::GO:0006970; P:response to osmotic stress; IMP:SGD.
2	Q6YFE4	143	GLRX5_LACKL Monothiol glutaredoxin-5, mitocho...	117	2e-66	204	80	92	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
3	Q9HDW8	146	GLRX5_SCHPO Monothiol glutaredoxin-5 OS=Schiz...	135	4e-44	148	56	69	GO:0005759; C:mitochondrial matrix; ISS:PomBase.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0008794; F:arsenate reductase (glutaredoxin) activity; TAS:PomBase.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; ISS:PomBase.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0071473; P:cellular response to cation stress; IEP:PomBase.::GO:0016226; P:iron-sulfur cluster assembly; ISS:PomBase.::GO:0019430; P:removal of superoxide radicals; IC:PomBase.::GO:0051409; P:response to nitrosative stress; TAS:PomBase.
4	Q6PBM1	155	GLRX5_DANRE Glutaredoxin-related protein 5, m...	127	4e-34	122	46	69	GO:0005739; C:mitochondrion; IDA:ZFIN.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0030097; P:hemopoiesis; IMP:ZFIN.::GO:0016226; P:iron-sulfur cluster assembly; IMP:ZFIN.
5	Q80Y14	152	GLRX5_MOUSE Glutaredoxin-related protein 5, m...	110	5e-34	122	50	75	GO:0005739; C:mitochondrion; IDA:UniProtKB.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.
6	Q555C8	143	GLRX5_DICDI Monothiol glutaredoxin-5, mitocho...	134	5e-33	119	43	64	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
7	Q86SX6	157	GLRX5_HUMAN Glutaredoxin-related protein 5, m...	108	1e-32	119	49	75	GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.
8	Q68W05	111	GLRX2_RICTY Probable monothiol glutaredoxin-2...	105	4e-30	111	48	68
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
9	Q0IWL9	491	GRS11_ORYSJ Monothiol glutaredoxin-S11 OS=Ory...	117	4e-22	95.5	38	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
10	Q28ID3	326	GLRX3_XENTR Glutaredoxin-3 OS=Xenopus tropica...	96	1e-24	101	47	66	GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
11	O05957	107	GLRX2_RICPR Probable monothiol glutaredoxin-2...	99	3e-27	103	47	67
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
12	Q1XDA3	107	YCF64_PORYE Uncharacterized monothiol glutare...	100	4e-27	103	44	63	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
13	Q84Y95	173	GRS14_ARATH Monothiol glutaredoxin-S14, chlor...	109	4e-27	104	44	63	GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009570; C:chloroplast stroma; IDA:TAIR.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0015297; F:antiporter activity; IDA:TAIR.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015038; F:glutathione disulfide oxidoreductase activity; IGI:TAIR.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0006812; P:cation transport; IDA:TAIR.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.
14	P73056	107	YC64L_SYNY3 Uncharacterized monothiol glutare...	109	5e-27	102	43	66
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
15	Q92GH5	107	GLRX2_RICCN Probable monothiol glutaredoxin-2...	99	6e-27	102	49	67
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
16	Q851Y7	168	GRXS7_ORYSJ Monothiol glutaredoxin-S7, chloro...	104	6e-27	104	46	65	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
17	Q9ZPH2	488	GRS17_ARATH Monothiol glutaredoxin-S17 OS=Ara...	106	1e-23	99.8	43	65	GO:0005829; C:cytosol; IDA:TAIR.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0009926; P:auxin polar transport; IMP:TAIR.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0072593; P:reactive oxygen species metabolic process; IMP:TAIR.::GO:0051726; P:regulation of cell cycle; IEP:TAIR.::GO:0009408; P:response to heat; IMP:TAIR.
18	P51384	107	YCF64_PORPU Uncharacterized monothiol glutare...	100	3e-26	100	43	63	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
19	O74790	244	GLRX4_SCHPO Monothiol glutaredoxin-4 OS=Schiz...	104	4e-26	103	43	66	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0008794; F:arsenate reductase (glutaredoxin) activity; TAS:PomBase.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; NAS:PomBase.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0019430; P:removal of superoxide radicals; IC:PomBase.
20	Q86H62	240	GLRX3_DICDI Glutaredoxin-3 homolog OS=Dictyos...	99	4e-26	103	43	67	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
21	Q4UK94	104	GLRX2_RICFE Probable monothiol glutaredoxin-2...	97	2e-25	99	47	65
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
22	P0AC72	115	GLRX4_SHIFL Glutaredoxin-4 OS=Shigella flexne...	115	1e-24	97.1	39	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
23	P0AC69	115	GLRX4_ECOLI Glutaredoxin-4 OS=Escherichia col...	115	1e-24	97.1	39	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IDA:EcoCyc.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
24	P0AC70	115	GLRX4_ECOL6 Glutaredoxin-4 OS=Escherichia col...	115	1e-24	97.1	39	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
25	P0AC71	115	GLRX4_ECO57 Glutaredoxin-4 OS=Escherichia col...	115	1e-24	97.1	39	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
26	Q5XJ54	326	GLRX3_DANRE Glutaredoxin 3 OS=Danio rerio (Ze...	104	1e-23	98.6	40	63	GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
27	Q8LBK6	169	GRS15_ARATH Monothiol glutaredoxin-S15, mitoc...	105	2e-24	97.8	39	63	GO:0005739; C:mitochondrion; IDA:TAIR.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
28	Q89AR8	108	GLRX4_BUCBP Glutaredoxin-4 OS=Buchnera aphidi...	98	2e-23	93.6	40	68	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
29	Q03835	285	GLRX3_YEAST Monothiol glutaredoxin-3 OS=Sacch...	88	2e-23	97.4	48	68	GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0030036; P:actin cytoskeleton organization; IMP:SGD.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006879; P:cellular iron ion homeostasis; IPI:SGD.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.
30	Q8H7F6	293	GRS16_ARATH Monothiol glutaredoxin-S16, chlor...	107	2e-23	97.4	42	67	GO:0009570; C:chloroplast stroma; IDA:TAIR.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0006812; P:cation transport; IDA:TAIR.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.
31	P32642	244	GLRX4_YEAST Monothiol glutaredoxin-4 OS=Sacch...	79	4e-23	95.9	49	73	GO:0005634; C:nucleus; IGI:SGD.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0030036; P:actin cytoskeleton organization; IMP:SGD.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006879; P:cellular iron ion homeostasis; IGI:SGD.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.

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