rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | Q9MYY8 | 499 | TRXR1_PIG Thioredoxin reductase 1, cytoplasmi... | 445 | 3e-21 | 100 | 23 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 212 | Q60151 | 450 | GSHR_STRTR Glutathione reductase OS=Streptoco... | 456 | 4e-21 | 99.4 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 213 | Q5NVA2 | 499 | TRXR1_PONAB Thioredoxin reductase 1, cytoplas... | 438 | 5e-21 | 99.8 | 23 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 214 | P35484 | 336 | DLDH_ACHLA Dihydrolipoyl dehydrogenase OS=Ach... | 329 | 6e-21 | 97.4 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 215 | Q16881 | 649 | TRXR1_HUMAN Thioredoxin reductase 1, cytoplas... | 438 | 7e-21 | 99.8 | 23 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; EXP:Reactome. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.::GO:0007165; P:signal transduction; NAS:ProtInc.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 216 | P39051 | 492 | TYTR_TRYBB Trypanothione reductase OS=Trypano... | 495 | 8e-20 | 95.9 | 25 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 217 | P77212 | 441 | YKGC_ECOLI Probable pyridine nucleotide-disul... | 496 | 1e-19 | 94.7 | 25 | 44 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 218 | Q99MD6 | 697 | TRXR3_MOUSE Thioredoxin reductase 3 OS=Mus mu... | 439 | 2e-19 | 95.1 | 24 | 43 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:MGI. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006749; P:glutathione metabolic process; IDA:MGI.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 219 | Q9NNW7 | 524 | TRXR2_HUMAN Thioredoxin reductase 2, mitochon... | 474 | 2e-19 | 94.7 | 23 | 41 | GO:0005739; C:mitochondrion; IDA:UniProtKB. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; ISS:UniProtKB. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB. | 220 | P06715 | 450 | GSHR_ECOLI Glutathione reductase OS=Escherich... | 457 | 3e-19 | 93.6 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:UniProtKB. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 221 | P28593 | 492 | TYTR_TRYCR Trypanothione reductase OS=Trypano... | 494 | 1e-18 | 92.4 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 222 | P91938 | 596 | TRXR1_DROME Thioredoxin reductase 1, mitochon... | 474 | 1e-17 | 89.4 | 22 | 41 | GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005739; C:mitochondrion; IDA:UniProtKB. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IMP:FlyBase.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:FlyBase.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IMP:UniProtKB.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0001666; P:response to hypoxia; IMP:FlyBase. | 223 | P39050 | 491 | TYTR_LEIDO Trypanothione reductase OS=Leishma... | 486 | 6e-17 | 87 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 224 | Q6BPI1 | 490 | GSHR_DEBHA Glutathione reductase OS=0083 / IG... | 493 | 1e-16 | 86.3 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 225 | P43783 | 456 | GSHR_HAEIN Glutathione reductase OS=Haemophil... | 448 | 1e-16 | 85.5 | 23 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 226 | Q17745 | 667 | TRXR1_CAEEL Thioredoxin reductase 1 OS=Caenor... | 514 | 2e-16 | 85.9 | 23 | 43 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0015036; F:disulfide oxidoreductase activity; NAS:UniProtKB.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; ISS:UniProtKB. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 227 | Q86VQ6 | 682 | TRXR3_HUMAN Thioredoxin reductase 3 OS=Homo s... | 530 | 4e-16 | 85.1 | 22 | 41 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; NAS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; NAS:UniProtKB.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 228 | O15770 | 500 | GSHR_PLAF7 Glutathione reductase OS=Plasmodiu... | 515 | 0.000000000000001 | 82.8 | 23 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 229 | Q94655 | 500 | GSHR_PLAFK Glutathione reductase OS=Plasmodiu... | 515 | 0.000000000000001 | 82.8 | 23 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 230 | P30635 | 503 | GSHR_CAEEL Probable glutathione reductase 2 O... | 495 | 0.000000000000005 | 81.3 | 21 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:WormBase. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 231 | O07927 | 459 | MTR_MYCTU Mycothione reductase OS=Mycobacteri... | 479 | 0.00000000000004 | 77.8 | 23 | 42 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IDA:MTBBASE.::GO:0050627; F:mycothione reductase activity; IDA:MTBBASE.::GO:0070402; F:NADPH binding; IDA:MTBBASE.::GO:0042803; F:protein homodimerization activity; IPI:MTBBASE. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0040007; P:growth; IMP:MTBBASE.::GO:0010126; P:mycothiol metabolic process; TAS:Reactome. | 232 | Q56839 | 523 | XECC_XANP2 2-oxopropyl-CoM reductase, carboxy... | 489 | 0.00000000000005 | 77.8 | 22 | 39 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050628; F:2-oxopropyl-CoM reductase (carboxylating) activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 233 | O53355 | 493 | LPDA_MYCTU NAD(P)H dehydrogenase (quinone) OS... | 490 | 0.000000000004 | 72 | 21 | 41 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IDA:MTBBASE.::GO:0003955; F:NAD(P)H dehydrogenase (quinone) activity; IDA:MTBBASE.::GO:0070401; F:NADP+ binding; IDA:MTBBASE. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009405; P:pathogenesis; IMP:MTBBASE.::GO:0051289; P:protein homotetramerization; IPI:MTBBASE. | 234 | P08662 | 460 | MERA_SERMA Mercuric reductase OS=Serratia mar... | 110 | 0.004 | 43.1 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro. | 235 | P80647 | 53 | DLDH_HYMDI Dihydrolipoyl dehydrogenase OS=Hym... | 47 | 0.0000001 | 53.1 | 49 | 74 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. | | | | | | | | | | | 236 | P71317 | 150 | STHA_PECCC Soluble pyridine nucleotide transh... | 117 | 0.00002 | 48.1 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 237 | P08655 | 180 | YMER_STAAU Uncharacterized 19.7 kDa protein i... | 107 | 0.0005 | 44.7 | 25 | 53 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 238 | Q96NN9 | 605 | AIFM3_HUMAN Apoptosis-inducing factor 3 OS=Ho... | 197 | 0.0007 | 45.8 | 25 | 43 | GO:0005783; C:endoplasmic reticulum; IDA:HGNC.::GO:0005743; C:mitochondrial inner membrane; IDA:HGNC. | | | | | | | | | | GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IDA:HGNC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; IDA:HGNC.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:HGNC.::GO:0051882; P:mitochondrial depolarization; IDA:HGNC.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 239 | P80880 | 316 | TRXB_BACSU Thioredoxin reductase OS=Bacillus ... | 310 | 0.0008 | 45.1 | 22 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0019430; P:removal of superoxide radicals; IEA:InterPro. | 240 | Q3TY86 | 605 | AIFM3_MOUSE Apoptosis-inducing factor 3 OS=Mu... | 197 | 0.001 | 45.4 | 25 | 43 | GO:0005783; C:endoplasmic reticulum; ISS:HGNC.::GO:0005743; C:mitochondrial inner membrane; ISS:HGNC. | | | | | | | | | | GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; ISS:HGNC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; ISS:HGNC.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:HGNC.::GO:0051882; P:mitochondrial depolarization; ISS:HGNC.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 241 | P66011 | 311 | TRXB_STAAW Thioredoxin reductase OS=Staphyloc... | 331 | 0.001 | 44.7 | 24 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0019430; P:removal of superoxide radicals; IEA:InterPro. |