Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL017C
Length:
499
Number of sequences:
5887
Description:
YPL017C IRC15 SGDID:S000005938, Chr XVI from 520233-518734, Genome Release 64-1-1, reverse complement, Verified ORF, "Microtubule associated protein; regulates microtubule dynamics; required for accurate meiotic chromosome segregation; null mutant displays large budded cells due to delayed mitotic progression, increased levels of spontaneous Rad52 foci"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q9MYY8    499   TRXR1_PIG Thioredoxin reductase 1, cytoplasmi...4453e-21     100     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
212Q60151    450   GSHR_STRTR Glutathione reductase OS=Streptoco...4564e-21     99.4     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
213Q5NVA2    499   TRXR1_PONAB Thioredoxin reductase 1, cytoplas...4385e-21     99.8     23     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
214P35484    336   DLDH_ACHLA Dihydrolipoyl dehydrogenase OS=Ach...3296e-21     97.4     29     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
215Q16881    649   TRXR1_HUMAN Thioredoxin reductase 1, cytoplas...4387e-21     99.8     23     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; EXP:Reactome.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.::GO:0007165; P:signal transduction; NAS:ProtInc.::GO:0006810; P:transport; IEA:UniProtKB-KW.
216P39051    492   TYTR_TRYBB Trypanothione reductase OS=Trypano...4958e-20     95.9     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
217P77212    441   YKGC_ECOLI Probable pyridine nucleotide-disul...4961e-19     94.7     25     44GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
218Q99MD6    697   TRXR3_MOUSE Thioredoxin reductase 3 OS=Mus mu...4392e-19     95.1     24     43GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:MGI.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006749; P:glutathione metabolic process; IDA:MGI.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
219Q9NNW7    524   TRXR2_HUMAN Thioredoxin reductase 2, mitochon...4742e-19     94.7     23     41GO:0005739; C:mitochondrion; IDA:UniProtKB.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; ISS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB.
220P06715    450   GSHR_ECOLI Glutathione reductase OS=Escherich...4573e-19     93.6     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:UniProtKB.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
221P28593    492   TYTR_TRYCR Trypanothione reductase OS=Trypano...4941e-18     92.4     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
222P91938    596   TRXR1_DROME Thioredoxin reductase 1, mitochon...4741e-17     89.4     22     41GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005739; C:mitochondrion; IDA:UniProtKB.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IMP:FlyBase.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:FlyBase.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB.
GO:0045454; P:cell redox homeostasis; IMP:UniProtKB.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0001666; P:response to hypoxia; IMP:FlyBase.
223P39050    491   TYTR_LEIDO Trypanothione reductase OS=Leishma...4866e-17     87     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
224Q6BPI1    490   GSHR_DEBHA Glutathione reductase OS=0083 / IG...4931e-16     86.3     24     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
225P43783    456   GSHR_HAEIN Glutathione reductase OS=Haemophil...4481e-16     85.5     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
226Q17745    667   TRXR1_CAEEL Thioredoxin reductase 1 OS=Caenor...5142e-16     85.9     23     43GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0015036; F:disulfide oxidoreductase activity; NAS:UniProtKB.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; ISS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
227Q86VQ6    682   TRXR3_HUMAN Thioredoxin reductase 3 OS=Homo s...5304e-16     85.1     22     41GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; NAS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; NAS:UniProtKB.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
228O15770    500   GSHR_PLAF7 Glutathione reductase OS=Plasmodiu...5150.000000000000001     82.8     23     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
229Q94655    500   GSHR_PLAFK Glutathione reductase OS=Plasmodiu...5150.000000000000001     82.8     23     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
230P30635    503   GSHR_CAEEL Probable glutathione reductase 2 O...4950.000000000000005     81.3     21     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:WormBase.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
231O07927    459   MTR_MYCTU Mycothione reductase OS=Mycobacteri...4790.00000000000004     77.8     23     42GO:0005829; C:cytosol; TAS:Reactome.
GO:0050660; F:flavin adenine dinucleotide binding; IDA:MTBBASE.::GO:0050627; F:mycothione reductase activity; IDA:MTBBASE.::GO:0070402; F:NADPH binding; IDA:MTBBASE.::GO:0042803; F:protein homodimerization activity; IPI:MTBBASE.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0040007; P:growth; IMP:MTBBASE.::GO:0010126; P:mycothiol metabolic process; TAS:Reactome.
232Q56839    523   XECC_XANP2 2-oxopropyl-CoM reductase, carboxy...4890.00000000000005     77.8     22     39GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050628; F:2-oxopropyl-CoM reductase (carboxylating) activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
233O53355    493   LPDA_MYCTU NAD(P)H dehydrogenase (quinone) OS...4900.000000000004     72     21     41GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IDA:MTBBASE.::GO:0003955; F:NAD(P)H dehydrogenase (quinone) activity; IDA:MTBBASE.::GO:0070401; F:NADP+ binding; IDA:MTBBASE.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009405; P:pathogenesis; IMP:MTBBASE.::GO:0051289; P:protein homotetramerization; IPI:MTBBASE.
234P08662    460   MERA_SERMA Mercuric reductase OS=Serratia mar...1100.004     43.1     29     47GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro.
235P80647    53   DLDH_HYMDI Dihydrolipoyl dehydrogenase OS=Hym...470.0000001     53.1     49     74GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
236P71317    150   STHA_PECCC Soluble pyridine nucleotide transh...1170.00002     48.1     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
237P08655    180   YMER_STAAU Uncharacterized 19.7 kDa protein i...1070.0005     44.7     25     53GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
238Q96NN9    605   AIFM3_HUMAN Apoptosis-inducing factor 3 OS=Ho...1970.0007     45.8     25     43GO:0005783; C:endoplasmic reticulum; IDA:HGNC.::GO:0005743; C:mitochondrial inner membrane; IDA:HGNC.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IDA:HGNC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; IDA:HGNC.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:HGNC.::GO:0051882; P:mitochondrial depolarization; IDA:HGNC.::GO:0006810; P:transport; IEA:UniProtKB-KW.
239P80880    316   TRXB_BACSU Thioredoxin reductase OS=Bacillus ...3100.0008     45.1     22     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0019430; P:removal of superoxide radicals; IEA:InterPro.
240Q3TY86    605   AIFM3_MOUSE Apoptosis-inducing factor 3 OS=Mu...1970.001     45.4     25     43GO:0005783; C:endoplasmic reticulum; ISS:HGNC.::GO:0005743; C:mitochondrial inner membrane; ISS:HGNC.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; ISS:HGNC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; ISS:HGNC.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:HGNC.::GO:0051882; P:mitochondrial depolarization; ISS:HGNC.::GO:0006810; P:transport; IEA:UniProtKB-KW.
241P66011    311   TRXB_STAAW Thioredoxin reductase OS=Staphyloc...3310.001     44.7     24     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0019430; P:removal of superoxide radicals; IEA:InterPro.
records
Previous ‹‹ ›› Next Total records: 498 211 - 240
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::