Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL017C
Length:
499
Number of sequences:
5887
Description:
YPL017C IRC15 SGDID:S000005938, Chr XVI from 520233-518734, Genome Release 64-1-1, reverse complement, Verified ORF, "Microtubule associated protein; regulates microtubule dynamics; required for accurate meiotic chromosome segregation; null mutant displays large budded cells due to delayed mitotic progression, increased levels of spontaneous Rad52 foci"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181Q6HA23    484   GSHR_KLULA Glutathione reductase OS=1267 / NR...4911e-27     119     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
182P00390    522   GSHR_HUMAN Glutathione reductase, mitochondri...4846e-27     117     25     45GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0004362; F:glutathione-disulfide reductase activity; TAS:Reactome.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
183Q873E8    468   GSHR_NEUCR Glutathione reductase OS=1257 / FG...4761e-26     115     24     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
184Q6FRV2    476   GSHR_CANGA Glutathione reductase OS=NRRL Y-65...4982e-26     115     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
185Q9VNT5    516   TRXR2_DROME Thioredoxin reductase 2, mitochon...4933e-26     115     24     43GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:FlyBase.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
186Q54465    557   MERA_SHEPU Mercuric reductase OS=Shewanella p...4736e-25     111     26     42GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro.
187Q8T137    465   GSHR_DICDI Glutathione reductase OS=Dictyoste...4861e-24     110     23     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:dictyBase.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0043295; F:glutathione binding; IDA:dictyBase.::GO:0004362; F:glutathione-disulfide reductase activity; IMP:dictyBase.::GO:0050661; F:NADP binding; IDA:dictyBase.
GO:0045454; P:cell redox homeostasis; IMP:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.::GO:0006749; P:glutathione metabolic process; IMP:dictyBase.
188Q6C5H4    470   GSHR_YARLI Glutathione reductase OS=lipolytic...4802e-24     109     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
189Q25861    541   TRXR_PLAF5 Thioredoxin reductase OS=Plasmodiu...5062e-24     110     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
190P78965    464   GSHR_SCHPO Glutathione reductase OS=Schizosac...4862e-24     108     25     43GO:0005739; C:mitochondrion; IDA:PomBase.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IMP:PomBase.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034599; P:cellular response to oxidative stress; IMP:PomBase.::GO:0006749; P:glutathione metabolic process; IMP:PomBase.
191P94188    559   MERA_ALCSP Mercuric reductase OS=Alcaligenes ...4732e-24     109     26     43GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro.
192Q74ZK4    480   GSHR_ASHGO Glutathione reductase OS=Y-1056) (...4733e-24     108     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
193P00392    561   MERA_PSEAI Mercuric reductase OS=Pseudomonas ...4446e-24     108     25     44GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro.
194Q52109    561   MERA_ACICA Mercuric reductase OS=Acinetobacte...4736e-24     108     26     44GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro.
195Q9N2I8    511   TRXR2_BOVIN Thioredoxin reductase 2, mitochon...4887e-24     108     23     42GO:0005739; C:mitochondrion; IDA:UniProtKB.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB.
196P41921    483   GSHR_YEAST Glutathione reductase OS=Saccharom...4999e-24     107     25     43GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IDA:SGD.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.::GO:0010731; P:protein glutathionylation; IGI:SGD.
197P61076    617   TRXR2_PLAF7 Thioredoxin reductase 2 OS=Plasmo...5069e-24     108     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
198P13110    492   TYTR_TRYCO Trypanothione reductase OS=Trypano...4932e-23     106     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
199O62768    499   TRXR1_BOVIN Thioredoxin reductase 1, cytoplas...4453e-23     106     24     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
200Q9Z0J5    526   TRXR2_RAT Thioredoxin reductase 2, mitochondr...4957e-23     105     23     41GO:0030424; C:axon; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:RGD.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0042493; P:response to drug; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; TAS:RGD.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB.::GO:0010269; P:response to selenium ion; IEP:RGD.
201B9A1H3    495   TRXR1_EMIHU Thioredoxin reductase SEP1 OS=Emi...4868e-23     104     25     40GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
202P94702    561   MERA_ENTAG Mercuric reductase OS=Enterobacter...4721e-22     104     26     45GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro.
203O89049    499   TRXR1_RAT Thioredoxin reductase 1, cytoplasmi...4382e-22     103     23     43GO:0005829; C:cytosol; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0045340; F:mercury ion binding; IDA:RGD.::GO:0016174; F:NAD(P)H oxidase activity; IDA:RGD.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0033797; F:selenate reductase activity; IDA:RGD.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:RGD.
GO:0042537; P:benzene-containing compound metabolic process; IDA:RGD.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0071280; P:cellular response to copper ion; IEP:RGD.::GO:0071455; P:cellular response to hyperoxia; IEP:RGD.::GO:0006749; P:glutathione metabolic process; IEP:RGD.::GO:0070276; P:halogen metabolic process; IEP:RGD.::GO:0042744; P:hydrogen peroxide catabolic process; IMP:RGD.::GO:0042191; P:methylmercury metabolic process; IEP:RGD.::GO:0070995; P:NADPH oxidation; IDA:RGD.::GO:0001890; P:placenta development; IEP:RGD.::GO:0010942; P:positive regulation of cell death; IMP:RGD.::GO:0051262; P:protein tetramerization; IDA:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0010269; P:response to selenium ion; IEP:RGD.::GO:0016259; P:selenocysteine metabolic process; IMP:RGD.
204P17239    547   MERA_THIFE Mercuric reductase OS=Thiobacillus...4723e-22     103     25     44GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro.
205P70619    424   GSHR_RAT Glutathione reductase OS=Rattus norv...4453e-22     102     24     44GO:0005829; C:cytosol; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0050660; F:flavin adenine dinucleotide binding; IDA:RGD.::GO:0043295; F:glutathione binding; IDA:RGD.::GO:0004362; F:glutathione-disulfide reductase activity; IDA:RGD.::GO:0050661; F:NADP binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IDA:RGD.::GO:0007283; P:spermatogenesis; IMP:RGD.
206P08332    564   MERA_SHIFL Mercuric reductase OS=Shigella fle...4504e-22     103     24     43GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro.
207Q51772    548   MERA_PSEFL Mercuric reductase OS=Pseudomonas ...4515e-22     102     25     43GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro.
208Q9JLT4    524   TRXR2_MOUSE Thioredoxin reductase 2, mitochon...4905e-22     102     22     42GO:0005739; C:mitochondrion; IDA:UniProtKB.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004791; F:thioredoxin-disulfide reductase activity; ISS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0007507; P:heart development; IMP:MGI.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB.
209P39040    491   TYTR_CRIFA Trypanothione reductase OS=Crithid...4821e-21     101     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
210Q9JMH6    613   TRXR1_MOUSE Thioredoxin reductase 1, cytoplas...4362e-21     101     22     43GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:MGI.
GO:0008283; P:cell proliferation; IMP:MGI.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0001707; P:mesoderm formation; IMP:MGI.
211Q9MYY8    499   TRXR1_PIG Thioredoxin reductase 1, cytoplasmi...4453e-21     100     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
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