rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | Q6HA23 | 484 | GSHR_KLULA Glutathione reductase OS=1267 / NR... | 491 | 1e-27 | 119 | 26 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 182 | P00390 | 522 | GSHR_HUMAN Glutathione reductase, mitochondri... | 484 | 6e-27 | 117 | 25 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0004362; F:glutathione-disulfide reductase activity; TAS:Reactome. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome. | 183 | Q873E8 | 468 | GSHR_NEUCR Glutathione reductase OS=1257 / FG... | 476 | 1e-26 | 115 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 184 | Q6FRV2 | 476 | GSHR_CANGA Glutathione reductase OS=NRRL Y-65... | 498 | 2e-26 | 115 | 26 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 185 | Q9VNT5 | 516 | TRXR2_DROME Thioredoxin reductase 2, mitochon... | 493 | 3e-26 | 115 | 24 | 43 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:FlyBase. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 186 | Q54465 | 557 | MERA_SHEPU Mercuric reductase OS=Shewanella p... | 473 | 6e-25 | 111 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro. | 187 | Q8T137 | 465 | GSHR_DICDI Glutathione reductase OS=Dictyoste... | 486 | 1e-24 | 110 | 23 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:dictyBase. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0043295; F:glutathione binding; IDA:dictyBase.::GO:0004362; F:glutathione-disulfide reductase activity; IMP:dictyBase.::GO:0050661; F:NADP binding; IDA:dictyBase. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IMP:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.::GO:0006749; P:glutathione metabolic process; IMP:dictyBase. | 188 | Q6C5H4 | 470 | GSHR_YARLI Glutathione reductase OS=lipolytic... | 480 | 2e-24 | 109 | 26 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 189 | Q25861 | 541 | TRXR_PLAF5 Thioredoxin reductase OS=Plasmodiu... | 506 | 2e-24 | 110 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 190 | P78965 | 464 | GSHR_SCHPO Glutathione reductase OS=Schizosac... | 486 | 2e-24 | 108 | 25 | 43 | GO:0005739; C:mitochondrion; IDA:PomBase. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IMP:PomBase.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034599; P:cellular response to oxidative stress; IMP:PomBase.::GO:0006749; P:glutathione metabolic process; IMP:PomBase. | 191 | P94188 | 559 | MERA_ALCSP Mercuric reductase OS=Alcaligenes ... | 473 | 2e-24 | 109 | 26 | 43 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro. | 192 | Q74ZK4 | 480 | GSHR_ASHGO Glutathione reductase OS=Y-1056) (... | 473 | 3e-24 | 108 | 25 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 193 | P00392 | 561 | MERA_PSEAI Mercuric reductase OS=Pseudomonas ... | 444 | 6e-24 | 108 | 25 | 44 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro. | 194 | Q52109 | 561 | MERA_ACICA Mercuric reductase OS=Acinetobacte... | 473 | 6e-24 | 108 | 26 | 44 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro. | 195 | Q9N2I8 | 511 | TRXR2_BOVIN Thioredoxin reductase 2, mitochon... | 488 | 7e-24 | 108 | 23 | 42 | GO:0005739; C:mitochondrion; IDA:UniProtKB. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB. | 196 | P41921 | 483 | GSHR_YEAST Glutathione reductase OS=Saccharom... | 499 | 9e-24 | 107 | 25 | 43 | GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IDA:SGD.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.::GO:0010731; P:protein glutathionylation; IGI:SGD. | 197 | P61076 | 617 | TRXR2_PLAF7 Thioredoxin reductase 2 OS=Plasmo... | 506 | 9e-24 | 108 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 198 | P13110 | 492 | TYTR_TRYCO Trypanothione reductase OS=Trypano... | 493 | 2e-23 | 106 | 25 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 199 | O62768 | 499 | TRXR1_BOVIN Thioredoxin reductase 1, cytoplas... | 445 | 3e-23 | 106 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 200 | Q9Z0J5 | 526 | TRXR2_RAT Thioredoxin reductase 2, mitochondr... | 495 | 7e-23 | 105 | 23 | 41 | GO:0030424; C:axon; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:RGD. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0042493; P:response to drug; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; TAS:RGD.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB.::GO:0010269; P:response to selenium ion; IEP:RGD. | 201 | B9A1H3 | 495 | TRXR1_EMIHU Thioredoxin reductase SEP1 OS=Emi... | 486 | 8e-23 | 104 | 25 | 40 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 202 | P94702 | 561 | MERA_ENTAG Mercuric reductase OS=Enterobacter... | 472 | 1e-22 | 104 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro. | 203 | O89049 | 499 | TRXR1_RAT Thioredoxin reductase 1, cytoplasmi... | 438 | 2e-22 | 103 | 23 | 43 | GO:0005829; C:cytosol; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0045340; F:mercury ion binding; IDA:RGD.::GO:0016174; F:NAD(P)H oxidase activity; IDA:RGD.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0033797; F:selenate reductase activity; IDA:RGD.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:RGD. | | | | | | | | | | GO:0042537; P:benzene-containing compound metabolic process; IDA:RGD.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0071280; P:cellular response to copper ion; IEP:RGD.::GO:0071455; P:cellular response to hyperoxia; IEP:RGD.::GO:0006749; P:glutathione metabolic process; IEP:RGD.::GO:0070276; P:halogen metabolic process; IEP:RGD.::GO:0042744; P:hydrogen peroxide catabolic process; IMP:RGD.::GO:0042191; P:methylmercury metabolic process; IEP:RGD.::GO:0070995; P:NADPH oxidation; IDA:RGD.::GO:0001890; P:placenta development; IEP:RGD.::GO:0010942; P:positive regulation of cell death; IMP:RGD.::GO:0051262; P:protein tetramerization; IDA:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0010269; P:response to selenium ion; IEP:RGD.::GO:0016259; P:selenocysteine metabolic process; IMP:RGD. | 204 | P17239 | 547 | MERA_THIFE Mercuric reductase OS=Thiobacillus... | 472 | 3e-22 | 103 | 25 | 44 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro. | 205 | P70619 | 424 | GSHR_RAT Glutathione reductase OS=Rattus norv... | 445 | 3e-22 | 102 | 24 | 44 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IDA:RGD.::GO:0043295; F:glutathione binding; IDA:RGD.::GO:0004362; F:glutathione-disulfide reductase activity; IDA:RGD.::GO:0050661; F:NADP binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IDA:RGD.::GO:0007283; P:spermatogenesis; IMP:RGD. | 206 | P08332 | 564 | MERA_SHIFL Mercuric reductase OS=Shigella fle... | 450 | 4e-22 | 103 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro. | 207 | Q51772 | 548 | MERA_PSEFL Mercuric reductase OS=Pseudomonas ... | 451 | 5e-22 | 102 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro. | 208 | Q9JLT4 | 524 | TRXR2_MOUSE Thioredoxin reductase 2, mitochon... | 490 | 5e-22 | 102 | 22 | 42 | GO:0005739; C:mitochondrion; IDA:UniProtKB. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004791; F:thioredoxin-disulfide reductase activity; ISS:UniProtKB. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0007507; P:heart development; IMP:MGI.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB. | 209 | P39040 | 491 | TYTR_CRIFA Trypanothione reductase OS=Crithid... | 482 | 1e-21 | 101 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 210 | Q9JMH6 | 613 | TRXR1_MOUSE Thioredoxin reductase 1, cytoplas... | 436 | 2e-21 | 101 | 22 | 43 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:MGI. | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:MGI.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0001707; P:mesoderm formation; IMP:MGI. | 211 | Q9MYY8 | 499 | TRXR1_PIG Thioredoxin reductase 1, cytoplasmi... | 445 | 3e-21 | 100 | 23 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. |