rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q9CBW6 | 237 | NPD_MYCLE NAD-dependent protein deacylase OS=... | 217 | 6e-17 | 82.4 | 32 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 92 | Q5KZE8 | 247 | NPD2_GEOKA NAD-dependent protein deacetylase ... | 182 | 6e-17 | 82.4 | 31 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 93 | P66813 | 237 | NPD_MYCTU NAD-dependent protein deacylase OS=... | 215 | 1e-16 | 81.6 | 32 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0003953; F:NAD+ nucleosidase activity; IDA:MTBBASE.::GO:0034979; F:NAD-dependent protein deacetylase activity; IDA:MTBBASE.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070213; P:protein auto-ADP-ribosylation; IDA:MTBBASE.::GO:0006476; P:protein deacetylation; IDA:MTBBASE. | 94 | P66814 | 237 | NPD_MYCBO NAD-dependent protein deacylase OS=... | 215 | 1e-16 | 81.6 | 32 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 95 | Q9I4E1 | 256 | NPD2_PSEAE NAD-dependent protein deacylase 2 ... | 213 | 4e-16 | 80.5 | 30 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 96 | Q9RL35 | 299 | NPD1_STRCO NAD-dependent protein deacetylase ... | 190 | 4e-16 | 81.3 | 31 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 97 | Q72IV5 | 254 | NPD_THET2 NAD-dependent protein deacylase OS=... | 218 | 5e-16 | 80.1 | 31 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 98 | Q8TWG0 | 250 | NPD_METKA NAD-dependent protein deacylase OS=... | 215 | 7e-16 | 79.3 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 99 | Q8R216 | 333 | SIR4_MOUSE NAD-dependent protein deacetylase ... | 233 | 9e-16 | 80.5 | 27 | 45 | GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 100 | Q8IRR5 | 312 | SIR4_DROME NAD-dependent protein deacetylase ... | 215 | 0.000000000000001 | 80.1 | 31 | 47 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 101 | Q73WM7 | 237 | NPD_MYCPA NAD-dependent protein deacylase OS=... | 213 | 0.000000000000002 | 78.2 | 31 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 102 | A0QC96 | 233 | NPD2_MYCA1 NAD-dependent protein deacylase 2 ... | 210 | 0.000000000000002 | 78.2 | 31 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 103 | Q5SIH7 | 254 | NPD_THET8 NAD-dependent protein deacylase OS=... | 218 | 0.000000000000002 | 78.2 | 31 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 104 | Q89EA6 | 273 | NPD2_BRAJA NAD-dependent protein deacetylase ... | 229 | 0.000000000000007 | 77 | 27 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 105 | E2RDZ6 | 310 | SIR5_CANFA NAD-dependent protein deacylase si... | 280 | 0.000000000000007 | 77.8 | 29 | 45 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 106 | A9SDL4 | 323 | SIR5_PHYPA NAD-dependent protein deacylase OS... | 231 | 0.00000000000001 | 77.4 | 30 | 43 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 107 | Q9Y6E7 | 314 | SIR4_HUMAN NAD-dependent protein deacetylase ... | 233 | 0.00000000000001 | 77 | 27 | 45 | GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006342; P:chromatin silencing; TAS:ProtInc.::GO:0046676; P:negative regulation of insulin secretion; IMP:UniProtKB.::GO:0006471; P:protein ADP-ribosylation; TAS:BHF-UCL.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 108 | Q8Y015 | 246 | NPD_RALSO NAD-dependent protein deacylase OS=... | 251 | 0.00000000000002 | 75.1 | 29 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 109 | Q1JQC6 | 315 | SIR4_BOVIN NAD-dependent protein deacetylase ... | 233 | 0.00000000000003 | 76.3 | 27 | 45 | GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 110 | Q5AI90 | 306 | SIR5_CANAL NAD-dependent protein deacylase OS... | 277 | 0.00000000000003 | 75.9 | 28 | 39 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 111 | Q8PDM9 | 293 | NPD_XANCP NAD-dependent protein deacetylase O... | 231 | 0.00000000000003 | 75.5 | 29 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 112 | Q4UZX0 | 293 | NPD_XANC8 NAD-dependent protein deacetylase O... | 231 | 0.00000000000003 | 75.5 | 29 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 113 | Q20480 | 287 | SIR41_CAEEL NAD-dependent protein deacetylase... | 281 | 0.00000000000004 | 75.1 | 25 | 43 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase. | 114 | Q5A1W9 | 487 | HST3_CANAL NAD-dependent histone deacetylase ... | 259 | 0.00000000000004 | 76.6 | 27 | 45 | | | | | | | | | | | GO:0004407; F:histone deacetylase activity; IMP:CGD.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048869; P:cellular developmental process; IMP:CGD.::GO:0071572; P:histone H3-K56 deacetylation; IMP:CGD.::GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0045595; P:regulation of cell differentiation; IMP:CGD. | 115 | A0QDH4 | 282 | NPD1_MYCA1 NAD-dependent protein deacetylase ... | 191 | 0.00000000000005 | 74.7 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019213; F:deacetylase activity; IEA:HAMAP.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:HAMAP. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 116 | Q5R6G3 | 310 | SIR5_PONAB NAD-dependent protein deacylase si... | 275 | 0.00000000000005 | 75.1 | 30 | 43 | GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006476; P:protein deacetylation; ISS:UniProtKB. | 117 | E9GD30 | 274 | SIR5_DAPPU NAD-dependent protein deacylase OS... | 254 | 0.00000000000006 | 74.3 | 29 | 44 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 118 | B0RM75 | 293 | NPD_XANCB NAD-dependent protein deacetylase O... | 231 | 0.0000000000001 | 74.3 | 29 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 119 | Q68FX9 | 310 | SIR5_RAT NAD-dependent protein deacylase sirt... | 257 | 0.0000000000001 | 74.3 | 30 | 43 | GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006476; P:protein deacetylation; ISS:UniProtKB. | 120 | Q8K2C6 | 310 | SIR5_MOUSE NAD-dependent protein deacylase si... | 258 | 0.0000000000001 | 74.3 | 30 | 43 | GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0036054; F:protein-malonyllysine demalonylase activity; IMP:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; ISS:UniProtKB. | 121 | Q9FE17 | 473 | SIR1_ARATH NAD-dependent protein deacetylase ... | 283 | 0.0000000000001 | 75.5 | 27 | 43 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. |