Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL006W
Length:
1170
Number of sequences:
5887
Description:
YPL006W NCR1 SGDID:S000005927, Chr XVI from 544631-548143, Genome Release 64-1-1, Verified ORF, "Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; glycoprotein and functional orthologue of human Niemann Pick C1 (NPC1) protein"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q88N31    1050   TTGB_PSEPK Probable efflux pump membrane tran...1530.00003     52.4     26     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
32P0C070    1050   MEPB_PSEPU Multidrug/solvent efflux pump memb...1530.00003     52.4     26     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
33Q9KJC2    1050   ARPB_PSEPU Antibiotic efflux pump membrane tr...1530.00003     52.4     26     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
34Q03602    844   PTR9_CAEEL Patched-related protein 9 OS=Caeno...1490.0002     49.3     23     49GO:0016021; C:integral to membrane; IEA:InterPro.
GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.
35O52248    1050   TTGB_PSEPU Toluene efflux pump membrane trans...1530.00003     52.4     26     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
36P37637    1037   MDTF_ECOLI Multidrug resistance protein MdtF ...2320.00003     52     22     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IMP:EcoliWiki.
GO:0006855; P:drug transmembrane transport; IMP:EcoliWiki.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
37P24181    1034   ACRF_ECOLI Acriflavine resistance protein F O...1540.00005     51.2     24     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
38P31224    1049   ACRB_ECOLI Acriflavine resistance protein B O...1540.00006     51.2     23     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015238; F:drug transmembrane transporter activity; IMP:EcoCyc.
39Q3TDN0    1521   DISP1_MOUSE Protein dispatched homolog 1 OS=M...1330.54     38.1     19     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008158; F:hedgehog receptor activity; IEA:InterPro.::GO:0015197; F:peptide transporter activity; IDA:MGI.
GO:0007368; P:determination of left/right symmetry; IMP:MGI.::GO:0009953; P:dorsal/ventral pattern formation; IMP:MGI.::GO:0009880; P:embryonic pattern specification; IMP:MGI.::GO:0007225; P:patched ligand maturation; IDA:MGI.
40Q6ZW05    846   PTHD4_HUMAN Patched domain-containing protein...1640.39     38.5     25     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
41Q96F81    1524   DISP1_HUMAN Protein dispatched homolog 1 OS=H...1330.73     37.7     19     44GO:0016323; C:basolateral plasma membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008158; F:hedgehog receptor activity; IEA:InterPro.::GO:0015197; F:peptide transporter activity; ISS:UniProtKB.
GO:0060539; P:diaphragm development; IMP:UniProtKB.::GO:0070207; P:protein homotrimerization; ISS:UniProtKB.::GO:0050708; P:regulation of protein secretion; ISS:UniProtKB.::GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB.
42Q6R5J2    1464   DISP1_DANRE Protein dispatched homolog 1 OS=D...1331.7     36.6     17     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
GO:0021984; P:adenohypophysis development; IMP:ZFIN.::GO:0009952; P:anterior/posterior pattern specification; IMP:ZFIN.::GO:0008015; P:blood circulation; IMP:ZFIN.::GO:0048701; P:embryonic cranial skeleton morphogenesis; IMP:ZFIN.::GO:0048839; P:inner ear development; IMP:ZFIN.::GO:0042694; P:muscle cell fate specification; IMP:ZFIN.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:ZFIN.::GO:0007519; P:skeletal muscle tissue development; IMP:ZFIN.::GO:0007224; P:smoothened signaling pathway; IMP:ZFIN.
43Q9KWV4    1048   TTGE_PSEPU Toluene efflux pump membrane trans...1550.001     47     23     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
44Q849R0    1046   SEPB_PSEP1 Probable efflux pump membrane tran...1550.001     47     23     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
45Q9VNJ5    1218   DISP_DROME Protein dispatched OS=Drosophila m...1940.002     46.6     25     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
GO:0006887; P:exocytosis; TAS:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007280; P:pole cell migration; IGI:FlyBase.::GO:0007224; P:smoothened signaling pathway; IMP:UniProtKB.
46Q8G2M6    1051   BEPE_BRUSU Efflux pump membrane transporter B...1500.002     46.6     23     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
47P24177    1037   ACRD_ECOLI Probable aminoglycoside efflux pum...1560.003     45.4     23     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015307; F:drug:hydrogen antiporter activity; IDA:EcoCyc.
48Q93PU4    1049   TTGH_PSEPU Toluene efflux pump membrane trans...1490.014     43.5     22     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
49O31100    1049   SRPB_PSEPU Solvent-resistant pump membrane tr...1490.014     43.5     22     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
50P16393    932   HMDH_STRPU 3-hydroxy-3-methylglutaryl-coenzym...2190.051     41.6     21     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
51Q9P2K9    1392   PTHD2_HUMAN Patched domain-containing protein...2030.46     38.5     24     43GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.
GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0032368; P:regulation of lipid transport; NAS:UniProtKB.::GO:0007224; P:smoothened signaling pathway; NAS:UniProtKB.
52A3KFU9    1347   PTHD2_MOUSE Patched domain-containing protein...2030.23     39.7     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
53O42335    257   PTC1_CYNPY Protein patched homolog 1 OS=Cynop...750.25     38.5     35     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
54P01027    1663   CO3_MOUSE Complement C3 OS=Mus musculus (Mous...1040.61     38.1     22     48GO:0005615; C:extracellular space; IEA:InterPro.
GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0006957; P:complement activation, alternative pathway; IEA:UniProtKB-KW.::GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0001970; P:positive regulation of activation of membrane attack complex; IMP:BHF-UCL.::GO:0045766; P:positive regulation of angiogenesis; IMP:BHF-UCL.::GO:0050766; P:positive regulation of phagocytosis; IMP:MGI.::GO:0001798; P:positive regulation of type IIa hypersensitivity; IMP:MGI.
55P01024    1663   CO3_HUMAN Complement C3 OS=Homo sapiens (Huma...1820.81     37.7     22     43GO:0005615; C:extracellular space; IEA:InterPro.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.::GO:0005102; F:receptor binding; TAS:ProtInc.
GO:0006957; P:complement activation, alternative pathway; TAS:Reactome.::GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0010575; P:positive regulation vascular endothelial growth factor production; IDA:BHF-UCL.
56Q14B62    888   PTHD1_MOUSE Patched domain-containing protein...2371.1     37.4     22     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
57Q12649    1176   HMDH_PHYBL 3-hydroxy-3-methylglutaryl-coenzym...1831.2     37     20     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
58A4WCC1    1040   MDTB_ENT38 Multidrug resistance protein MdtB ...1601.3     37     24     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
59A7MHJ1    1040   MDTB_CROS8 Multidrug resistance protein MdtB ...1601.7     36.6     25     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
60A8GHQ9    1039   MDTB_SERP5 Multidrug resistance protein MdtB ...1602     36.2     23     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
61Q58957    388   Y1562_METJA Putative membrane protein MJ1562 ...1352.1     35.8     24     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
records
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