Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL003W
Length:
462
Number of sequences:
5887
Description:
YPL003W ULA1 SGDID:S000005924, Chr XVI from 552020-553408, Genome Release 64-1-1, Verified ORF, "Protein that acts together with Uba3p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q12059    462   ULA1_YEAST NEDD8-activating enzyme E1 regulat...4620     955     100     100
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0045116; P:protein neddylation; IDA:SGD.
2Q9Z1A5    534   ULA1_RAT NEDD8-activating enzyme E1 regulator...5432e-38     150     27     46GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:RGD.
3Q6NTW6    533   ULA1_XENLA NEDD8-activating enzyme E1 regulat...5383e-38     150     26     45
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
4Q13564    534   ULA1_HUMAN NEDD8-activating enzyme E1 regulat...5386e-38     149     26     46GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005626; C:insoluble fraction; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IDA:UniProtKB.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; IDA:UniProtKB.::GO:0045116; P:protein neddylation; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
5Q4R3L6    510   ULA1_MACFA NEDD8-activating enzyme E1 regulat...5288e-38     148     27     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
6Q8VBW6    534   ULA1_MOUSE NEDD8-activating enzyme E1 regulat...5431e-37     148     27     45GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
7Q7SXP2    533   ULA1_DANRE NEDD8-activating enzyme E1 regulat...5372e-37     147     25     47
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
8Q54JM3    520   ULA1_DICDI NEDD8-activating enzyme E1 regulat...5353e-37     146     27     46
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0045116; P:protein neddylation; ISS:dictyBase.
9Q9UT93    517   ULA1_SCHPO NEDD8-activating enzyme E1 regulat...5331e-35     142     26     47GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; ISS:PomBase.
GO:0045116; P:protein neddylation; ISS:PomBase.
10Q5ZIE6    535   ULA1_CHICK NEDD8-activating enzyme E1 regulat...5492e-34     138     25     45
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
11P42744    540   ULA1_ARATH NEDD8-activating enzyme E1 regulat...440.005     42.7     41     64GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003824; F:catalytic activity; IEA:InterPro.
GO:0010252; P:auxin homeostasis; NAS:TAIR.::GO:0009734; P:auxin mediated signaling pathway; IMP:TAIR.::GO:0006281; P:DNA repair; IMP:TAIR.::GO:0009965; P:leaf morphogenesis; IGI:TAIR.::GO:0016567; P:protein ubiquitination; IGI:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.
12Q9VTE9    524   ULA1_DROME NEDD8-activating enzyme E1 regulat...5342e-23     106     25     41GO:0005626; C:insoluble fraction; ISS:UniProtKB.::GO:0043234; C:protein complex; IPI:FlyBase.
GO:0001540; F:beta-amyloid binding; IPI:UniProtKB.::GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
GO:0045116; P:protein neddylation; ISS:UniProtKB.
13Q18217    541   ULA1_CAEEL NEDD8-activating enzyme E1 regulat...430.00003     50.1     47     67
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
14Q9R1T2    350   SAE1_MOUSE SUMO-activating enzyme subunit 1 O...1630.000000000002     72     33     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
15Q6AXQ0    349   SAE1_RAT SUMO-activating enzyme subunit 1 OS=...1870.000000000005     70.5     30     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
16Q5NVN7    346   SAE1_PONAB SUMO-activating enzyme subunit 1 O...1870.000000000009     69.7     30     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
17Q9UBE0    346   SAE1_HUMAN SUMO-activating enzyme subunit 1 O...1870.000000000009     69.7     30     45GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0043008; F:ATP-dependent protein binding; IDA:UniProtKB.::GO:0008047; F:enzyme activator activity; TAS:ProtInc.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IDA:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0004839; F:ubiquitin activating enzyme activity; TAS:UniProtKB.
GO:0016925; P:protein sumoylation; IDA:UniProtKB.::GO:0016567; P:protein ubiquitination; TAS:UniProtKB.
18A2VE14    346   SAE1_BOVIN SUMO-activating enzyme subunit 1 O...1870.00000000003     68.2     30     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
19Q28DS0    347   SAE1_XENTR SUMO-activating enzyme subunit 1 O...1680.0000000007     63.9     32     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
20Q8JGT5    344   SAE1_XENLA SUMO-activating enzyme subunit 1 O...1680.000000004     61.6     32     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
21P79064    307   RAD31_SCHPO DNA damage tolerance protein rad3...1910.00000006     57.8     27     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0031510; C:SUMO activating enzyme complex; TAS:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019948; F:SUMO activating enzyme activity; ISS:PomBase.
GO:0016925; P:protein sumoylation; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IGI:PomBase.::GO:0006974; P:response to DNA damage stimulus; IMP:PomBase.
22Q6IQS6    348   SAE1_DANRE SUMO-activating enzyme subunit 1 O...1690.0000004     55.5     30     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
23Q54WI4    330   SAE1_DICDI SUMO-activating enzyme subunit 1 O...670.00002     50.4     39     58GO:0031510; C:SUMO activating enzyme complex; ISS:dictyBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019948; F:SUMO activating enzyme activity; ISS:dictyBase.
GO:0016925; P:protein sumoylation; ISS:dictyBase.
24P0DI13    320   SA1B2_ARATH SUMO-activating enzyme subunit 1B...490.0001     47.4     49     65GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
25P0DI12    320   SA1B1_ARATH SUMO-activating enzyme subunit 1B...490.0001     47.4     49     65GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
26Q17820    343   SAE1_CAEEL SUMO-activating enzyme subunit aos...354.5     33.1     43     60
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0040019; P:positive regulation of embryonic development; IMP:WormBase.::GO:0016925; P:protein sumoylation; IDA:WormBase.
27Q8VY78    322   SAE1A_ARATH SUMO-activating enzyme subunit 1A...490.0009     44.7     43     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
28Q06624    347   RHC31_YEAST DNA damage tolerance protein RHC3...671     35.4     30     49GO:0031510; C:SUMO activating enzyme complex; IPI:SGD.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019948; F:SUMO activating enzyme activity; IDA:SGD.
GO:0016925; P:protein sumoylation; IDA:SGD.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
29P92974    1077   UBE12_ARATH Ubiquitin-activating enzyme E1 2 ...520.39     37     44     58GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; TAS:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
30P41226    1012   UBA7_HUMAN Ubiquitin-like modifier-activating...493.1     34.3     45     55GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019782; F:ISG15 activating enzyme activity; IDA:HGNC.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032020; P:ISG15-protein conjugation; IDA:HGNC.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
31Q46IW3    691   EFG_PROMT Elongation factor G OS=Prochlorococ...1204.5     33.5     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
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