rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q5JEZ2 | 333 | GYAR_PYRKO Glyoxylate reductase OS=(Thermococ... | 273 | 4e-21 | 95.9 | 29 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 32 | A5GFY8 | 533 | SERA_PIG D-3-phosphoglycerate dehydrogenase O... | 279 | 9e-21 | 97.1 | 30 | 46 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 33 | Q9Z2F5 | 430 | CTBP1_RAT C-terminal-binding protein 1 OS=Rat... | 232 | 1e-20 | 95.9 | 29 | 48 | GO:0005829; C:cytosol; IDA:RGD.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IDA:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:RGD.::GO:0016746; F:transferase activity, transferring acyl groups; TAS:RGD. | | | | | | | | | | GO:0006944; P:cellular membrane fusion; TAS:RGD.::GO:0007030; P:Golgi organization; IMP:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 34 | O88712 | 441 | CTBP1_MOUSE C-terminal-binding protein 1 OS=M... | 232 | 1e-20 | 95.9 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB. | 35 | Q9YAW4 | 335 | GYAR_AERPE Glyoxylate reductase OS=100138 / K... | 268 | 1e-20 | 94.4 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 36 | Q13363 | 440 | CTBP1_HUMAN C-terminal-binding protein 1 OS=H... | 230 | 2e-20 | 95.9 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0090241; P:negative regulation of histone H4 acetylation; IMP:BHF-UCL.::GO:0031065; P:positive regulation of histone deacetylation; IMP:BHF-UCL.::GO:0006468; P:protein phosphorylation; TAS:ProtInc.::GO:0051726; P:regulation of cell cycle; IMP:BHF-UCL.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:BHF-UCL.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 37 | Q9YHU0 | 440 | CTBP1_XENLA C-terminal-binding protein 1 OS=X... | 232 | 2e-20 | 95.1 | 29 | 47 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB. | 38 | Q61753 | 533 | SERA_MOUSE D-3-phosphoglycerate dehydrogenase... | 279 | 2e-20 | 95.9 | 29 | 44 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; TAS:MGI. | | | | | | | | | | GO:0022402; P:cell cycle process; IMP:MGI.::GO:0009448; P:gamma-aminobutyric acid metabolic process; IMP:MGI.::GO:0021782; P:glial cell development; IMP:MGI.::GO:0006541; P:glutamine metabolic process; IMP:MGI.::GO:0006544; P:glycine metabolic process; IMP:MGI.::GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW.::GO:0021915; P:neural tube development; IMP:MGI.::GO:0031175; P:neuron projection development; IMP:MGI.::GO:0010468; P:regulation of gene expression; IMP:MGI.::GO:0021510; P:spinal cord development; IMP:MGI.::GO:0019530; P:taurine metabolic process; IMP:MGI.::GO:0006566; P:threonine metabolic process; IMP:MGI. | 39 | A5A6P1 | 533 | SERA_PANTR D-3-phosphoglycerate dehydrogenase... | 279 | 3e-20 | 95.5 | 30 | 45 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 40 | O43175 | 533 | SERA_HUMAN D-3-phosphoglycerate dehydrogenase... | 306 | 3e-20 | 95.5 | 28 | 44 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; TAS:Reactome. | | | | | | | | | | GO:0007420; P:brain development; TAS:ProtInc.::GO:0006564; P:L-serine biosynthetic process; TAS:Reactome. | 41 | B5EX58 | 324 | GHRB_SALA4 Glyoxylate/hydroxypyruvate reducta... | 248 | 4e-20 | 93.2 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 42 | Q9W758 | 437 | CTBP2_XENLA C-terminal-binding protein 2 OS=X... | 232 | 4e-20 | 94.7 | 28 | 48 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 43 | B5RGN1 | 324 | GHRB_SALG2 Glyoxylate/hydroxypyruvate reducta... | 248 | 4e-20 | 93.2 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 44 | O08651 | 533 | SERA_RAT D-3-phosphoglycerate dehydrogenase O... | 279 | 4e-20 | 95.1 | 29 | 44 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IDA:RGD. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 45 | B4SWJ5 | 324 | GHRB_SALNS Glyoxylate/hydroxypyruvate reducta... | 248 | 4e-20 | 92.8 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 46 | B5R4N3 | 324 | GHRB_SALEP Glyoxylate/hydroxypyruvate reducta... | 248 | 4e-20 | 92.8 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 47 | B5FLC2 | 324 | GHRB_SALDC Glyoxylate/hydroxypyruvate reducta... | 248 | 4e-20 | 92.8 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 48 | Q8Z2A8 | 324 | GHRB_SALTI Glyoxylate/hydroxypyruvate reducta... | 248 | 4e-20 | 92.8 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 49 | Q8ZLA1 | 324 | GHRB_SALTY Glyoxylate/hydroxypyruvate reducta... | 248 | 4e-20 | 92.8 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 50 | B4T938 | 324 | GHRB_SALHS Glyoxylate/hydroxypyruvate reducta... | 248 | 4e-20 | 92.8 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 51 | Q6DB24 | 320 | GHRB_ERWCT Glyoxylate/hydroxypyruvate reducta... | 249 | 5e-20 | 92.8 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 52 | B7LTG7 | 324 | GHRB_ESCF3 Glyoxylate/hydroxypyruvate reducta... | 241 | 5e-20 | 92.8 | 28 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 53 | Q60HD7 | 533 | SERA_MACFA D-3-phosphoglycerate dehydrogenase... | 279 | 6e-20 | 94.7 | 29 | 44 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 54 | C0Q1A7 | 324 | GHRB_SALPC Glyoxylate/hydroxypyruvate reducta... | 248 | 8e-20 | 92 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 55 | Q57IH8 | 324 | GHRB_SALCH Glyoxylate/hydroxypyruvate reducta... | 248 | 8e-20 | 92 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 56 | B5BHT3 | 324 | GHRB_SALPK Glyoxylate/hydroxypyruvate reducta... | 248 | 8e-20 | 92 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 57 | Q5PLL9 | 324 | GHRB_SALPA Glyoxylate/hydroxypyruvate reducta... | 248 | 8e-20 | 92 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 58 | Q0VCQ1 | 445 | CTBP2_BOVIN C-terminal-binding protein 2 OS=B... | 230 | 1e-19 | 93.2 | 30 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 59 | A9MUT4 | 324 | GHRB_SALPB Glyoxylate/hydroxypyruvate reducta... | 248 | 1e-19 | 91.7 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 60 | O94574 | 340 | YGDH_SCHPO Putative 2-hydroxyacid dehydrogena... | 240 | 2e-19 | 91.7 | 28 | 44 | GO:0005739; C:mitochondrion; ISS:PomBase.::GO:0005634; C:nucleus; ISS:PomBase. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; ISS:PomBase.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0009436; P:glyoxylate catabolic process; ISS:PomBase.::GO:0006111; P:regulation of gluconeogenesis; IC:PomBase. | 61 | Q47748 | 323 | VANH_ENTFA D-specific alpha-keto acid dehydro... | 225 | 2e-19 | 90.9 | 29 | 46 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. |