UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOR374W

Length:

519

Number of sequences:

5887

Description:

YOR374W ALD4 SGDID:S000005901, Chr XV from 1039840-1041399, Genome Release 64-1-1, Verified ORF, "Mitochondrial aldehyde dehydrogenase, required for growth on ethanol and conversion of acetaldehyde to acetate; phosphorylated; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
331	P94391	515	ROCA2_BACSU 1-pyrroline-5-carboxylate dehydro...	466	5e-75	252	33	52
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
332	P51649	535	SSDH_HUMAN Succinate-semialdehyde dehydrogena...	471	9e-75	252	34	56	GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005625; C:soluble fraction; IDA:UniProtKB.
									GO:0042803; F:protein homodimerization activity; IC:UniProtKB.::GO:0004777; F:succinate-semialdehyde dehydrogenase activity; IDA:UniProtKB.
									GO:0006083; P:acetate metabolic process; ISS:UniProtKB.::GO:0007417; P:central nervous system development; IMP:UniProtKB.::GO:0006681; P:galactosylceramide metabolic process; ISS:UniProtKB.::GO:0009450; P:gamma-aminobutyric acid catabolic process; IDA:UniProtKB.::GO:0006006; P:glucose metabolic process; ISS:UniProtKB.::GO:0006536; P:glutamate metabolic process; ISS:UniProtKB.::GO:0006541; P:glutamine metabolic process; ISS:UniProtKB.::GO:0006749; P:glutathione metabolic process; ISS:UniProtKB.::GO:0006650; P:glycerophospholipid metabolic process; ISS:UniProtKB.::GO:0042135; P:neurotransmitter catabolic process; ISS:UniProtKB.::GO:0007269; P:neurotransmitter secretion; TAS:Reactome.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0022904; P:respiratory electron transport chain; ISS:UniProtKB.::GO:0046459; P:short-chain fatty acid metabolic process; ISS:UniProtKB.::GO:0006105; P:succinate metabolic process; ISS:UniProtKB.
333	P62028	515	ROCA_BACC1 1-pyrroline-5-carboxylate dehydrog...	469	1e-74	251	34	52
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
334	Q9K9B2	515	ROCA1_BACHD 1-pyrroline-5-carboxylate dehydro...	529	1e-74	251	32	51
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
335	Q6HP91	515	ROCA_BACHK 1-pyrroline-5-carboxylate dehydrog...	469	1e-74	251	34	52
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
336	Q63GS0	515	ROCA_BACCZ 1-pyrroline-5-carboxylate dehydrog...	469	1e-74	251	34	52
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
337	B9J1L9	515	ROCA_BACCQ 1-pyrroline-5-carboxylate dehydrog...	469	1e-74	251	34	52
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
338	B7HSW8	515	ROCA_BACC7 1-pyrroline-5-carboxylate dehydrog...	469	1e-74	251	34	52
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
339	C1EV77	515	ROCA_BACC3 1-pyrroline-5-carboxylate dehydrog...	469	1e-74	251	34	52
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
340	B7JM99	515	ROCA_BACC0 1-pyrroline-5-carboxylate dehydrog...	469	1e-74	251	34	52
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
341	Q81ZF8	515	ROCA_BACAN 1-pyrroline-5-carboxylate dehydrog...	469	1e-74	251	34	52
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
342	A0R909	515	ROCA_BACAH 1-pyrroline-5-carboxylate dehydrog...	469	1e-74	251	34	52
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
343	C3L546	515	ROCA_BACAC 1-pyrroline-5-carboxylate dehydrog...	469	1e-74	251	34	52
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
344	C3PBP4	515	ROCA_BACAA 1-pyrroline-5-carboxylate dehydrog...	469	1e-74	251	34	52
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
345	Q9KAH5	485	IOLA_BACHD Methylmalonate semialdehyde dehydr...	475	1e-74	250	32	53
									GO:0018478; F:malonate-semialdehyde dehydrogenase (acetylating) activity; IEA:EC.::GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating) activity; IEA:EC.
346	Q9K5Z5	515	ROCA2_BACHD 1-pyrroline-5-carboxylate dehydro...	463	2e-74	250	33	54
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
347	Q8EMV4	486	IOLA2_OCEIH Methylmalonate semialdehyde dehyd...	476	3e-74	249	31	53
									GO:0018478; F:malonate-semialdehyde dehydrogenase (acetylating) activity; IEA:EC.::GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating) activity; IEA:EC.
348	Q6A2H1	535	SSDH_GORGO Succinate-semialdehyde dehydrogena...	471	3e-74	251	34	56	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
									GO:0004777; F:succinate-semialdehyde dehydrogenase activity; ISS:UniProtKB.
									GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0009450; P:gamma-aminobutyric acid catabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
349	Q3MSM4	535	SSDH_PANPA Succinate-semialdehyde dehydrogena...	471	3e-74	251	34	56	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
									GO:0004777; F:succinate-semialdehyde dehydrogenase activity; ISS:UniProtKB.
									GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0009450; P:gamma-aminobutyric acid catabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
350	P0A390	483	NAHF_PSEU8 Salicylaldehyde dehydrogenase OS=P...	473	3e-74	249	32	52
									GO:0018485; F:salicylaldehyde dehydrogenase activity; IEA:EC.
									GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
351	P0A391	483	NAHF_PSEPU Salicylaldehyde dehydrogenase OS=P...	473	3e-74	249	32	52
									GO:0018485; F:salicylaldehyde dehydrogenase activity; IEA:EC.
									GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
352	Q6A2H2	535	SSDH_PONPY Succinate-semialdehyde dehydrogena...	471	4e-74	250	34	56	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
									GO:0004777; F:succinate-semialdehyde dehydrogenase activity; ISS:UniProtKB.
									GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0009450; P:gamma-aminobutyric acid catabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
353	Q6A2H0	535	SSDH_PANTR Succinate-semialdehyde dehydrogena...	471	7e-74	249	34	56	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
									GO:0004777; F:succinate-semialdehyde dehydrogenase activity; ISS:UniProtKB.
									GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0009450; P:gamma-aminobutyric acid catabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
354	A4IPF5	483	IOLA2_GEOTN Methylmalonate semialdehyde dehyd...	476	2e-73	247	34	53
									GO:0018478; F:malonate-semialdehyde dehydrogenase (acetylating) activity; IEA:EC.::GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating) activity; IEA:EC.
355	Q4A0E7	514	ROCA_STAS1 1-pyrroline-5-carboxylate dehydrog...	492	6e-73	246	34	54
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
356	Q8ES27	486	IOLA1_OCEIH Methylmalonate semialdehyde dehyd...	433	6e-73	246	33	56
									GO:0018478; F:malonate-semialdehyde dehydrogenase (acetylating) activity; IEA:EC.::GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating) activity; IEA:EC.
357	Q8ERF4	515	ROCA_OCEIH 1-pyrroline-5-carboxylate dehydrog...	466	1e-71	243	32	53
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
358	Q53197	512	Y4UC_RHISN Putative aldehyde-dehydrogenase-li...	412	4e-71	241	36	53
									GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
359	Q5WH11	486	IOLA2_BACSK Methylmalonate semialdehyde dehyd...	432	5e-71	240	33	55
									GO:0018478; F:malonate-semialdehyde dehydrogenase (acetylating) activity; IEA:EC.::GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating) activity; IEA:EC.
360	A8F9T1	515	ROCA_BACP2 1-pyrroline-5-carboxylate dehydrog...	468	1e-70	240	32	50
									GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:InterPro.
361	Q4V1F6	487	IOLA3_BACCZ Methylmalonate semialdehyde dehyd...	479	3e-70	238	31	53
									GO:0018478; F:malonate-semialdehyde dehydrogenase (acetylating) activity; IEA:EC.::GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating) activity; IEA:EC.

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