Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR367W
Length:
200
Number of sequences:
5887
Description:
YOR367W SCP1 SGDID:S000005894, Chr XV from 1026007-1026609, Genome Release 64-1-1, Verified ORF, "Component of yeast cortical actin cytoskeleton, binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P46940    1657   IQGA1_HUMAN Ras GTPase-activating-like protei...1120.052     37.7     21     49GO:0005884; C:actin filament; TAS:ProtInc.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0036057; C:slit diaphragm; ISS:UniProtKB.
GO:0005516; F:calmodulin binding; TAS:ProtInc.::GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0005099; F:Ras GTPase activator activity; IEA:InterPro.
GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
62P62046    709   LRCH1_MOUSE Leucine-rich repeat and calponin ...1260.052     37.7     29     44
63Q9Y2L9    728   LRCH1_HUMAN Leucine-rich repeat and calponin ...1070.097     37     30     41
64Q54TK8    1502   GEFP_DICDI Ras guanine nucleotide exchange fa...1050.1     37     30     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
65O75427    683   LRCH4_HUMAN Leucine-rich repeat and calponin ...730.14     36.6     34     48GO:0016605; C:PML body; IDA:MGI.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007399; P:nervous system development; TAS:ProtInc.
66Q7M7Q6    262   SPEE_WOLSU Spermidine synthase OS=Wolinella s...1030.15     35.8     29     50
GO:0004766; F:spermidine synthase activity; IEA:EC.
GO:0008295; P:spermidine biosynthetic process; IEA:UniProtKB-KW.
67P15498    845   VAV_HUMAN Proto-oncogene vav OS=Homo sapiens ...910.28     35.4     27     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.
68Q921G6    680   LRCH4_MOUSE Leucine-rich repeat and calponin ...720.31     35.4     35     49
69Q08DN7    844   VAV_BOVIN Proto-oncogene vav OS=Bos taurus (B...910.38     35     27     43GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
70P54100    843   VAV_RAT Proto-oncogene vav OS=Rattus norvegic...480.44     35     40     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0048468; P:cell development; TAS:RGD.::GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; IEP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
71P27870    845   VAV_MOUSE Proto-oncogene vav OS=Mus musculus ...480.46     34.7     40     56GO:0005829; C:cytosol; TAS:Reactome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IGI:MGI.
GO:0006955; P:immune response; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0006909; P:phagocytosis; IGI:MGI.::GO:0045785; P:positive regulation of cell adhesion; IGI:MGI.::GO:0043087; P:regulation of GTPase activity; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0030217; P:T cell differentiation; TAS:MGI.
72Q8JZP9    678   GA2L1_MOUSE GAS2-like protein 1 OS=Mus muscul...1860.48     34.7     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; ISS:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0009267; P:cellular response to starvation; IDA:UniProtKB.::GO:0097067; P:cellular response to thyroid hormone stimulus; ISS:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0045647; P:negative regulation of erythrocyte differentiation; ISS:UniProtKB.::GO:0010629; P:negative regulation of gene expression; ISS:UniProtKB.::GO:0007026; P:negative regulation of microtubule depolymerization; ISS:UniProtKB.
73Q8K4I3    771   ARHG6_MOUSE Rho guanine nucleotide exchange f...1130.63     34.3     26     44GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
74Q5XXR3    772   ARHG6_RAT Rho guanine nucleotide exchange fac...1130.76     34.3     26     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
75Q3UMG5    773   LRCH2_MOUSE Leucine-rich repeat and calponin ...1211.1     33.5     28     46
76Q15052    776   ARHG6_HUMAN Rho guanine nucleotide exchange f...1131.3     33.5     27     44GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0007254; P:JNK cascade; NAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
77Q5VUJ6    765   LRCH2_HUMAN Leucine-rich repeat and calponin ...1211.3     33.5     28     46
78B8J4F3    163   MOAC_DESDA Molybdenum cofactor biosynthesis p...572.6     31.6     30     51
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
79A6UQ84    406   APGM_METVS 2,3-bisphosphoglycerate-independen...717.9     30.8     25     46
GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004619; F:phosphoglycerate mutase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
80Q74NK2    299   NFI_NANEQ Bifunctional methyltransferase-like...838.7     30.4     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0043737; F:deoxyribonuclease V activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
81Q99501    681   GA2L1_HUMAN GAS2-like protein 1 OS=Homo sapie...1079.2     30.8     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IDA:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.
GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0009267; P:cellular response to starvation; ISS:UniProtKB.::GO:0097067; P:cellular response to thyroid hormone stimulus; IDA:UniProtKB.::GO:0001578; P:microtubule bundle formation; IMP:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0045647; P:negative regulation of erythrocyte differentiation; IDA:UniProtKB.::GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.::GO:0007026; P:negative regulation of microtubule depolymerization; IMP:UniProtKB.::GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.
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