Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR367W
Length:
200
Number of sequences:
5887
Description:
YOR367W SCP1 SGDID:S000005894, Chr XV from 1026007-1026609, Genome Release 64-1-1, Verified ORF, "Component of yeast cortical actin cytoskeleton, binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P51911    297   CNN1_HUMAN Calponin-1 OS=Homo sapiens (Human)...1890.00000005     55.1     26     44GO:0005856; C:cytoskeleton; IDA:MGI.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0031032; P:actomyosin structure organization; IEA:InterPro.::GO:0006940; P:regulation of smooth muscle contraction; TAS:UniProtKB.
32P37397    330   CNN3_RAT Calponin-3 OS=Rattus norvegicus (Rat...1990.00000008     54.7     26     44GO:0005884; C:actin filament; TAS:RGD.::GO:0005874; C:microtubule; TAS:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0014069; C:postsynaptic density; IDA:RGD.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:RGD.::GO:0030674; F:protein binding, bridging; NAS:RGD.
GO:0031032; P:actomyosin structure organization; IEA:InterPro.::GO:0032780; P:negative regulation of ATPase activity; IDA:RGD.
33Q9DAW9    330   CNN3_MOUSE Calponin-3 OS=Mus musculus (Mouse)...1990.0000001     54.3     26     44
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0031032; P:actomyosin structure organization; IEA:InterPro.
34Q5RFN6    309   CNN2_PONAB Calponin-2 OS=Pongo abelii (Sumatr...1470.0000003     52.8     27     45
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0031032; P:actomyosin structure organization; IEA:InterPro.
35Q99439    309   CNN2_HUMAN Calponin-2 OS=Homo sapiens (Human)...1470.0000003     52.8     27     45GO:0005911; C:cell-cell junction; TAS:ProtInc.::GO:0001725; C:stress fiber; IDA:MGI.
GO:0003779; F:actin binding; TAS:ProtInc.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0031032; P:actomyosin structure organization; IEA:InterPro.::GO:0071260; P:cellular response to mechanical stimulus; IDA:MGI.::GO:0032970; P:regulation of actin filament-based process; IDA:MGI.
36Q3SYU6    309   CNN2_BOVIN Calponin-2 OS=Bos taurus (Bovine)....1470.000002     50.8     26     45
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0031032; P:actomyosin structure organization; IEA:InterPro.
37Q9UKW4    847   VAV3_HUMAN Guanine nucleotide exchange factor...870.000002     50.8     34     54GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0006974; P:response to DNA damage stimulus; IMP:UniProtKB.::GO:0042493; P:response to drug; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
38Q08093    305   CNN2_MOUSE Calponin-2 OS=Mus musculus (Mouse)...1470.000002     50.4     27     44
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0031032; P:actomyosin structure organization; IEA:InterPro.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0030336; P:negative regulation of cell migration; IMP:MGI.::GO:0050765; P:negative regulation of phagocytosis; IMP:MGI.::GO:0010628; P:positive regulation of gene expression; IMP:MGI.::GO:0042127; P:regulation of cell proliferation; IMP:MGI.::GO:0042060; P:wound healing; IMP:MGI.
39Q08094    296   CNN2_PIG Calponin-2 OS=Sus scrofa (Pig). GN=C...1470.000006     49.3     27     44
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0031032; P:actomyosin structure organization; IEA:InterPro.
40Q9R0C8    847   VAV3_MOUSE Guanine nucleotide exchange factor...870.00002     47.8     33     53GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005154; F:epidermal growth factor receptor binding; IPI:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IGI:MGI.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IGI:MGI.::GO:0007229; P:integrin-mediated signaling pathway; IGI:MGI.::GO:0030032; P:lamellipodium assembly; IGI:MGI.::GO:0045785; P:positive regulation of cell adhesion; IGI:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IGI:MGI.::GO:0043087; P:regulation of GTPase activity; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IMP:MGI.::GO:0006906; P:vesicle fusion; IGI:MGI.
41Q12280    1495   IQG1_YEAST Ras GTPase-activating-like protein...1230.0002     45.1     29     46GO:0000142; C:cellular bud neck contractile ring; TAS:SGD.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005099; F:Ras GTPase activator activity; IEA:InterPro.
GO:0007015; P:actin filament organization; IPI:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:SGD.::GO:0006970; P:response to osmotic stress; TAS:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
42Q3UWW6    683   GA2L3_MOUSE GAS2-like protein 3 OS=Mus muscul...1450.0003     44.3     28     44
GO:0007050; P:cell cycle arrest; IEA:InterPro.
43O43903    313   GAS2_HUMAN Growth arrest-specific protein 2 O...1220.001     42.4     30     46GO:0005884; C:actin filament; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
44P11862    314   GAS2_MOUSE Growth arrest-specific protein 2 O...1220.002     42     30     43GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
45P52735    878   VAV2_HUMAN Guanine nucleotide exchange factor...1000.002     42.4     30     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
46Q60992    868   VAV2_MOUSE Guanine nucleotide exchange factor...1000.002     42     30     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005154; F:epidermal growth factor receptor binding; IPI:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IGI:MGI.::GO:0030032; P:lamellipodium assembly; IGI:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IMP:MGI.
47Q13576    1575   IQGA2_HUMAN Ras GTPase-activating-like protei...1370.003     41.6     23     47GO:0015629; C:actin cytoskeleton; TAS:ProtInc.
GO:0003779; F:actin binding; TAS:ProtInc.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.::GO:0005099; F:Ras GTPase activator activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
48Q3UQ44    1575   IQGA2_MOUSE Ras GTPase-activating-like protei...1370.003     41.6     23     47GO:0005622; C:intracellular; IEA:InterPro.::GO:0005902; C:microvillus; IDA:MGI.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005099; F:Ras GTPase activator activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
49Q86XJ1    694   GA2L3_HUMAN GAS2-like protein 3 OS=Homo sapie...1020.007     40.4     28     47
GO:0007050; P:cell cycle arrest; IEA:InterPro.
50Q8NHY3    880   GA2L2_HUMAN GAS2-like protein 2 OS=Homo sapie...1200.008     40.4     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0008093; F:cytoskeletal adaptor activity; IDA:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0001578; P:microtubule bundle formation; IMP:UniProtKB.::GO:0007026; P:negative regulation of microtubule depolymerization; IMP:UniProtKB.
51Q86VI3    1631   IQGA3_HUMAN Ras GTPase-activating-like protei...1120.008     40.4     22     49
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005099; F:Ras GTPase activator activity; IEA:InterPro.
52Q96II8    777   LRCH3_HUMAN Leucine-rich repeat and calponin ...1020.01     40     30     47GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
53Q5ZLR6    764   ARHG6_CHICK Rho guanine nucleotide exchange f...1190.017     39.3     33     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
54Q5SSG4    860   GA2L2_MOUSE GAS2-like protein 2 OS=Mus muscul...1200.018     39.3     30     42GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0008093; F:cytoskeletal adaptor activity; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0007026; P:negative regulation of microtubule depolymerization; ISS:UniProtKB.
55Q55GV9    686   LIMCH_DICDI Calponin homology and LIM domain-...1250.02     38.9     28     45GO:0030863; C:cortical cytoskeleton; IDA:dictyBase.::GO:0005829; C:cytosol; IDA:dictyBase.::GO:0001891; C:phagocytic cup; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; ISS:dictyBase.
GO:0046847; P:filopodium assembly; IMP:dictyBase.::GO:0050765; P:negative regulation of phagocytosis; IMP:dictyBase.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.
56O14188    1489   RNG2_SCHPO Ras GTPase-activating-like protein...1120.021     38.9     25     44GO:0005826; C:actomyosin contractile ring; IDA:PomBase.::GO:0030428; C:cell septum; IDA:UniProtKB.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IDA:UniProtKB.
GO:0003779; F:actin binding; IDA:PomBase.::GO:0005516; F:calmodulin binding; IPI:UniProtKB.::GO:0005099; F:Ras GTPase activator activity; IEA:InterPro.
GO:0071519; P:actin filament bundle assembly involved in actomyosin contractile ring formation; IDA:PomBase.::GO:0071520; P:actin filament bundle convergence involved in actomyosin contractile ring formation; IDA:PomBase.::GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
57Q45FX5    1007   VAV_CAEEL Protein vav-1 OS=Caenorhabditis ele...910.021     38.9     33     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0045746; P:negative regulation of Notch signaling pathway; IGI:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
58Q8BVU0    778   LRCH3_MOUSE Leucine-rich repeat and calponin ...980.021     38.9     31     47GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
59P41737    251   LRCH1_FELCA Leucine-rich repeat and calponin ...1210.029     38.1     30     43
60Q9JKF1    1657   IQGA1_MOUSE Ras GTPase-activating-like protei...1120.042     38.1     21     49GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0036057; C:slit diaphragm; ISS:UniProtKB.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005099; F:Ras GTPase activator activity; IEA:InterPro.
GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
61P46940    1657   IQGA1_HUMAN Ras GTPase-activating-like protei...1120.052     37.7     21     49GO:0005884; C:actin filament; TAS:ProtInc.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0036057; C:slit diaphragm; ISS:UniProtKB.
GO:0005516; F:calmodulin binding; TAS:ProtInc.::GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0005099; F:Ras GTPase activator activity; IEA:InterPro.
GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
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