Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR351C
Length:
497
Number of sequences:
5887
Description:
YOR351C MEK1 SGDID:S000005878, Chr XV from 996511-995018, Genome Release 64-1-1, reverse complement, Verified ORF, "Meiosis-specific serine/threonine protein kinase, functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
481Q9Y2H1    464   ST38L_HUMAN Serine/threonine-protein kinase 3...2631e-21     101     29     46GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0051128; P:regulation of cellular component organization; ISS:UniProtKB.
482P27448    753   MARK3_HUMAN MAP/microtubule affinity-regulati...2881e-21     102     30     47GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
483O88445    282   AURKC_MOUSE Aurora kinase C OS=Mus musculus (...3001e-21     98.6     25     47GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000793; C:condensed chromosome; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
484Q8R4U9    367   SGK2_RAT Serine/threonine-protein kinase Sgk2...3161e-21     99.8     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015459; F:potassium channel regulator activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
485Q61846    643   MELK_MOUSE Maternal embryonic leucine zipper ...2411e-21     102     28     51GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
486B2DD29    778   BRSK1_RAT Serine/threonine-protein kinase BRS...2611e-21     102     30     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0051298; P:centrosome duplication; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0007269; P:neurotransmitter secretion; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
487Q69Q47    453   CIPKO_ORYSJ CBL-interacting protein kinase 24...3021e-21     100     27     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
488Q5RJI5    778   BRSK1_MOUSE Serine/threonine-protein kinase B...2611e-21     102     30     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0008021; C:synaptic vesicle; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
GO:0007409; P:axonogenesis; IMP:UniProtKB.::GO:0051298; P:centrosome duplication; IMP:UniProtKB.::GO:0030010; P:establishment of cell polarity; IMP:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007269; P:neurotransmitter secretion; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.
489P40376    512   KAPB_SCHPO cAMP-dependent protein kinase cata...2911e-21     101     30     46GO:0005952; C:cAMP-dependent protein kinase complex; TAS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IGI:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0001315; P:age-dependent response to reactive oxygen species; IMP:PomBase.::GO:0019933; P:cAMP-mediated signaling; IC:PomBase.::GO:0001300; P:chronological cell aging; IGI:PomBase.::GO:0031142; P:induction of conjugation upon nitrogen starvation; IMP:PomBase.::GO:0031138; P:negative regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0006110; P:regulation of glycolysis; NAS:PomBase.
490O94547    580   SRK1_SCHPO Serine/threonine-protein kinase sr...2671e-21     101     29     45GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:PomBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; TAS:PomBase.::GO:0040020; P:regulation of meiosis; IMP:PomBase.::GO:0007088; P:regulation of mitosis; IPI:PomBase.::GO:0031098; P:stress-activated protein kinase signaling cascade; IGI:PomBase.
491Q19469    914   SAD1_CAEEL Serine/threonine kinase SAD-1 OS=C...2771e-21     102     29     49GO:0030424; C:axon; IDA:WormBase.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030425; C:dendrite; IDA:WormBase.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:WormBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase.::GO:0050321; F:tau-protein kinase activity; IDA:WormBase.
GO:0008088; P:axon cargo transport; IGI:WormBase.::GO:0007411; P:axon guidance; IMP:WormBase.::GO:0034613; P:cellular protein localization; IGI:WormBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0030516; P:regulation of axon extension; IMP:WormBase.::GO:0007416; P:synapse assembly; IMP:WormBase.::GO:0048489; P:synaptic vesicle transport; IMP:WormBase.
492Q3U3Q1    472   ULK3_MOUSE Serine/threonine-protein kinase UL...3281e-21     100     28     48GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
493Q6P4S6    1311   SIK3_MOUSE Serine/threonine-protein kinase SI...2402e-21     102     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
494Q8W1D5    488   CIPKP_ARATH CBL-interacting serine/threonine-...3272e-21     100     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0050832; P:defense response to fungus; IEP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
495Q64595    762   KGP2_RAT cGMP-dependent protein kinase 2 OS=R...3272e-21     101     30     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC.
496Q99JP0    894   M4K3_MOUSE Mitogen-activated protein kinase k...3022e-21     102     30     48
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.
497Q8GVC7    399   PKZ1_PHYIN Serine/threonine-protein kinase PK...3152e-21     99.8     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
498Q06850    610   CDPK1_ARATH Calcium-dependent protein kinase ...2832e-21     101     27     47GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.
499Q64303    524   PAK2_RAT Serine/threonine-protein kinase PAK ...2932e-21     100     28     46GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
500Q86IX1    737   DST1_DICDI Serine/threonine-protein kinase ds...3062e-21     101     30     46GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0006915; P:apoptotic process; ISS:dictyBase.::GO:0008283; P:cell proliferation; ISS:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase.
501Q8CIN4    524   PAK2_MOUSE Serine/threonine-protein kinase PA...2932e-21     100     28     46GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
502Q9LEU7    445   CIPK5_ARATH CBL-interacting serine/threonine-...2962e-21     100     26     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
503P24723    683   KPCL_HUMAN Protein kinase C eta type OS=Homo ...2932e-21     101     29     48GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; TAS:ProtInc.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; IMP:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; IMP:UniProtKB.::GO:0045618; P:positive regulation of keratinocyte differentiation; ISS:UniProtKB.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:2000810; P:regulation of tight junction assembly; IMP:UniProtKB.
504Q61410    762   KGP2_MOUSE cGMP-dependent protein kinase 2 OS...3272e-21     101     30     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC.
505O22932    435   CIPKB_ARATH CBL-interacting serine/threonine-...2932e-21     99.8     26     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009268; P:response to pH; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
506Q6DE08    361   AUKBA_XENLA Aurora kinase B-A OS=Xenopus laev...2972e-21     99     27     47
507Q8INB9    611   AKT1_DROME RAC serine/threonine-protein kinas...3322e-21     100     28     47GO:0009986; C:cell surface; IDA:FlyBase.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; NAS:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; NAS:FlyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006916; P:anti-apoptosis; IMP:FlyBase.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008362; P:chitin-based embryonic cuticle biosynthetic process; IGI:FlyBase.::GO:0007427; P:epithelial cell migration, open tracheal system; IMP:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0035556; P:intracellular signal transduction; IGI:UniProtKB.::GO:0019915; P:lipid storage; IGI:FlyBase.::GO:0060292; P:long term synaptic depression; IMP:FlyBase.::GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.::GO:0045793; P:positive regulation of cell size; IMP:FlyBase.::GO:0040018; P:positive regulation of multicellular organism growth; TAS:FlyBase.::GO:0046622; P:positive regulation of organ growth; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0050773; P:regulation of dendrite development; IMP:FlyBase.::GO:0042306; P:regulation of protein import into nucleus; TAS:FlyBase.
508Q29502    524   PAK2_RABIT Serine/threonine-protein kinase PA...2932e-21     100     28     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0097194; P:execution phase of apoptosis; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
509Q5JLS2    540   CIPKC_ORYSJ CBL-interacting protein kinase 12...2922e-21     100     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
510Q9SMQ4    350   SRK2F_ARATH Serine/threonine-protein kinase S...2882e-21     98.6     30     44GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009651; P:response to salt stress; IDA:TAIR.
511Q6PHR2    472   ULK3_HUMAN Serine/threonine-protein kinase UL...2972e-21     100     28     50GO:0000407; C:pre-autophagosomal structure; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006914; P:autophagy; TAS:UniProtKB.::GO:0090398; P:cellular senescence; TAS:UniProtKB.::GO:0045879; P:negative regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
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