Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR351C
Length:
497
Number of sequences:
5887
Description:
YOR351C MEK1 SGDID:S000005878, Chr XV from 996511-995018, Genome Release 64-1-1, reverse complement, Verified ORF, "Meiosis-specific serine/threonine protein kinase, functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
451Q02595    510   KPK2_PLAFK Probable serine/threonine-protein ...2895e-22     102     27     46GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
452O00444    970   PLK4_HUMAN Serine/threonine-protein kinase PL...3005e-22     103     28     50GO:0005814; C:centriole; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; IMP:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0046601; P:positive regulation of centriole replication; IMP:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
453Q753D9    726   PKH3_ASHGO Serine/threonine-protein kinase PK...2556e-22     103     31     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
454Q5PU49    674   KPCD_CANFA Protein kinase C delta type OS=Can...2876e-22     103     28     49GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030837; P:negative regulation of actin filament polymerization; ISS:UniProtKB.::GO:0051490; P:negative regulation of filopodium assembly; ISS:UniProtKB.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0032930; P:positive regulation of superoxide anion generation; ISS:UniProtKB.
455Q7YRC6    344   AURKB_BOVIN Aurora kinase B OS=Bos taurus (Bo...2996e-22     100     27     46GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
456Q63644    1369   ROCK1_RAT Rho-associated protein kinase 1 OS=...2356e-22     103     31     49GO:0032059; C:bleb; IEA:UniProtKB-SubCell.::GO:0005814; C:centriole; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017049; F:GTP-Rho binding; IMP:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; NAS:RGD.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IEA:InterPro.::GO:0007010; P:cytoskeleton organization; IMP:RGD.::GO:0007266; P:Rho protein signal transduction; IMP:MGI.
457Q7TSE6    464   ST38L_MOUSE Serine/threonine-protein kinase 3...2636e-22     102     29     46GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0051128; P:regulation of cellular component organization; IDA:UniProtKB.
458Q5R9Z7    970   PLK4_PONAB Serine/threonine-protein kinase PL...3006e-22     103     28     50GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
459P70335    1354   ROCK1_MOUSE Rho-associated protein kinase 1 O...2356e-22     103     31     49GO:0032059; C:bleb; IEA:UniProtKB-SubCell.::GO:0005814; C:centriole; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0032060; P:bleb assembly; IMP:MGI.::GO:0000910; P:cytokinesis; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.
460Q13464    1354   ROCK1_HUMAN Rho-associated protein kinase 1 O...2356e-22     103     31     49GO:0032059; C:bleb; IEA:UniProtKB-SubCell.::GO:0005814; C:centriole; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0000910; P:cytokinesis; IEA:InterPro.::GO:0050901; P:leukocyte tethering or rolling; IDA:BHF-UCL.::GO:0022614; P:membrane to membrane docking; IDA:BHF-UCL.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:2000145; P:regulation of cell motility; TAS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; TAS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; TAS:UniProtKB.::GO:0045616; P:regulation of keratinocyte differentiation; IMP:UniProtKB.::GO:0051492; P:regulation of stress fiber assembly; TAS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.::GO:0006939; P:smooth muscle contraction; TAS:UniProtKB.
461B4IAQ8    769   PLK4_DROSE Serine/threonine-protein kinase PL...2556e-22     103     29     48GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
462B4QK53    769   PLK4_DROSI Serine/threonine-protein kinase PL...2556e-22     103     29     49GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
463O77819    1354   ROCK1_RABIT Rho-associated protein kinase 1 O...2357e-22     103     31     49GO:0032059; C:bleb; IEA:UniProtKB-SubCell.::GO:0005814; C:centriole; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
464Q7ZX15    486   AKT2A_XENLA RAC-beta serine/threonine-protein...2777e-22     102     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
465Q9N2L7    632   PLK2_CAEEL Serine/threonine-protein kinase pl...2717e-22     102     30     47GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:WormBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; NAS:UniProtKB.::GO:0060631; P:regulation of meiosis I; IMP:WormBase.
466Q8IVH8    894   M4K3_HUMAN Mitogen-activated protein kinase k...2987e-22     103     30     48
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0007254; P:JNK cascade; TAS:ProtInc.
467P48562    842   CLA4_YEAST Serine/threonine-protein kinase CL...2267e-22     102     30     49GO:0005933; C:cellular bud; IDA:SGD.::GO:0000324; C:fungal-type vacuole; IDA:SGD.::GO:0005634; C:nucleus; IMP:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:SGD.
GO:0007118; P:budding cell apical bud growth; TAS:SGD.::GO:0000910; P:cytokinesis; TAS:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0010629; P:negative regulation of gene expression; IMP:SGD.::GO:0007096; P:regulation of exit from mitosis; IMP:SGD.::GO:0019236; P:response to pheromone; IGI:SGD.::GO:0007266; P:Rho protein signal transduction; TAS:SGD.::GO:0035376; P:sterol import; IMP:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD.
468Q755C4    367   IPL1_ASHGO Spindle assembly checkpoint kinase...2837e-22     100     28     48GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
469Q01919    800   KIN4_YEAST Serine/threonine-protein kinase KI...2957e-22     102     28     47GO:0005938; C:cell cortex; IDA:SGD.::GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005816; C:spindle pole body; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:SGD.
GO:0031578; P:mitotic cell cycle spindle orientation checkpoint; IMP:SGD.
470Q9Y2K2    1263   SIK3_HUMAN Serine/threonine-protein kinase SI...2408e-22     103     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
471O95382    1288   M3K6_HUMAN Mitogen-activated protein kinase k...2788e-22     103     29     47
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.
472Q2V452    441   CIPK3_ARATH CBL-interacting serine/threonine-...2978e-22     101     27     46GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0009628; P:response to abiotic stimulus; IEP:TAIR.::GO:0009735; P:response to cytokinin stimulus; IEP:TAIR.
473D7UQM5    407   AURK_ASTPE Aurora kinase OS=Asterina pectinif...3028e-22     100     26     48GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
474Q8C0X8    640   SMKX_MOUSE Sperm motility kinase X OS=Mus mus...2659e-22     102     32     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
475Q8VHF0    797   MARK3_RAT MAP/microtubule affinity-regulating...2889e-22     102     30     47GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
476Q6IP76    485   AKT2B_XENLA RAC-beta serine/threonine-protein...2721e-21     101     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
477Q5ZJH6    468   ULK3_CHICK Serine/threonine-protein kinase UL...2951e-21     101     29     48GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
478Q13237    762   KGP2_HUMAN cGMP-dependent protein kinase 2 OS...2921e-21     102     31     48GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.::GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.::GO:0007165; P:signal transduction; TAS:ProtInc.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
479Q9SJ61    520   CDPKP_ARATH Calcium-dependent protein kinase ...2271e-21     101     28     50GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
480Q96PN8    268   TSSK3_HUMAN Testis-specific serine/threonine-...2901e-21     98.6     28     46
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
481Q9Y2H1    464   ST38L_HUMAN Serine/threonine-protein kinase 3...2631e-21     101     29     46GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0051128; P:regulation of cellular component organization; ISS:UniProtKB.
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