UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOR347C

Length:

506

Number of sequences:

5887

Description:

YOR347C PYK2 SGDID:S000005874, Chr XV from 986462-984942, Genome Release 64-1-1, reverse complement, Verified ORF, "Pyruvate kinase that appears to be modulated by phosphorylation; PYK2 transcription is repressed by glucose, and Pyk2p may be active under low glycolytic flux"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P52489	506	KPYK2_YEAST Pyruvate kinase 2 OS=Saccharomyce...	506	0	1040	100	100	GO:0005739; C:mitochondrion; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IMP:SGD.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006090; P:pyruvate metabolic process; IMP:SGD.
2	Q6FV12	508	KPYK2_CANGA Pyruvate kinase 2 OS=NRRL Y-65) (...	503	0	766	71	87
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
3	Q6FIS9	501	KPYK1_CANGA Pyruvate kinase 1 OS=NRRL Y-65) (...	499	0	753	72	86
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
4	Q875S4	501	KPYK_LACKL Pyruvate kinase OS=Lachancea kluyv...	500	0	749	70	85
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
5	P00549	500	KPYK1_YEAST Pyruvate kinase 1 OS=Saccharomyce...	499	0	744	71	85	GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IDA:SGD.
									GO:0006096; P:glycolysis; IMP:SGD.::GO:0006090; P:pyruvate metabolic process; IMP:SGD.
6	Q875Z9	501	KPYK_NAUCC Pyruvate kinase OS=Y-12630) (Yeast...	498	0	733	71	84
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
7	Q875M9	501	KPYK_KLULA Pyruvate kinase OS=1267 / NRRL Y-1...	500	0	729	68	84
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
8	Q759A9	501	KPYK_ASHGO Pyruvate kinase OS=Y-1056) (Yeast)...	500	0	719	69	84
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
9	P46614	504	KPYK_CANAL Pyruvate kinase OS=Candida albican...	501	0	697	64	82	GO:0009986; C:cell surface; IDA:CGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030446; C:hyphal cell wall; IDA:CGD.::GO:0005886; C:plasma membrane; IDA:CGD.::GO:0005625; C:soluble fraction; IDA:CGD.::GO:0030445; C:yeast-form cell wall; IDA:CGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; ISS:CGD.
									GO:0030447; P:filamentous growth; IMP:CGD.::GO:0006096; P:glycolysis; ISS:CGD.::GO:0044416; P:induction by symbiont of host defense response; IDA:CGD.
10	Q6BS75	504	KPYK_DEBHA Pyruvate kinase OS=0083 / IGC 2968...	501	0	682	63	81
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
11	P30614	515	KPYK_YARLI Pyruvate kinase OS=lipolytica). GN...	503	0	658	62	79
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
12	Q12669	526	KPYK_ASPNG Pyruvate kinase OS=Aspergillus nig...	493	0	650	62	79
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
13	P22360	526	KPYK_EMENI Pyruvate kinase OS=194 / M139) (As...	493	0	649	61	79
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
14	Q10208	509	KPYK_SCHPO Pyruvate kinase OS=Schizosaccharom...	491	0	615	61	76	GO:0005829; C:cytosol; IDA:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; ISS:PomBase.
									GO:0006096; P:glycolysis; ISS:PomBase.::GO:0070317; P:negative regulation of G0 to G1 transition; IMP:PomBase.::GO:0006090; P:pyruvate metabolic process; ISS:PomBase.
15	Q7RVA8	527	KPYK_NEUCR Pyruvate kinase OS=1257 / FGSC 987...	501	0	611	59	76
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
16	P31865	538	KPYK_HYPJE Pyruvate kinase OS=Hypocrea jecori...	501	0	606	60	75
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
17	O94122	532	KPYK_AGABI Pyruvate kinase OS=Agaricus bispor...	486	0	561	59	76
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
18	P30613	574	KPYR_HUMAN Pyruvate kinase isozymes R/L OS=Ho...	510	8e-170	499	50	67	GO:0005829; C:cytosol; TAS:Reactome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; TAS:ProtInc.
									GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0006096; P:glycolysis; TAS:Reactome.::GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.
19	P12928	574	KPYR_RAT Pyruvate kinase isozymes R/L OS=Ratt...	510	1e-167	493	50	67	GO:0005829; C:cytosol; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IDA:RGD.
									GO:0006754; P:ATP biosynthetic process; IDA:RGD.::GO:0032869; P:cellular response to insulin stimulus; IDA:RGD.::GO:0006096; P:glycolysis; IDA:RGD.::GO:0042866; P:pyruvate biosynthetic process; IDA:RGD.::GO:0033198; P:response to ATP; IDA:RGD.::GO:0051591; P:response to cAMP; IDA:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009408; P:response to heat; IDA:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0010226; P:response to lithium ion; IDA:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.
20	Q29536	574	KPYR_CANFA Pyruvate kinase isozymes R/L OS=Ca...	510	6e-167	491	49	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
21	P53657	574	KPYR_MOUSE Pyruvate kinase isozymes R/L OS=Mu...	510	9e-165	486	49	67	GO:0005829; C:cytosol; TAS:Reactome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
22	Q92122	527	KPYK_XENLA Pyruvate kinase muscle isozyme OS=...	510	5e-163	479	48	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
23	P14618	531	KPYM_HUMAN Pyruvate kinase isozymes M1/M2 OS=...	510	3e-160	473	47	65	GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004743; F:pyruvate kinase activity; IEA:InterPro.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0012501; P:programmed cell death; IDA:UniProtKB.
24	O62619	533	KPYK_DROME Pyruvate kinase OS=Drosophila mela...	509	2e-159	471	48	66	GO:0005829; C:cytosol; IDA:FlyBase.::GO:0005811; C:lipid particle; IDA:FlyBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; NAS:UniProtKB.
									GO:0006096; P:glycolysis; NAS:UniProtKB.
25	Q27686	499	KPYK_LEIME Pyruvate kinase OS=Leishmania mexi...	498	3e-158	466	49	65
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
26	P11980	531	KPYM_RAT Pyruvate kinase isozymes M1/M2 OS=Ra...	510	5e-157	464	46	65	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
									GO:0043531; F:ADP binding; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004743; F:pyruvate kinase activity; IDA:RGD.
									GO:0006754; P:ATP biosynthetic process; IDA:RGD.::GO:0006096; P:glycolysis; IDA:RGD.::GO:0001889; P:liver development; IDA:RGD.::GO:0031100; P:organ regeneration; IDA:RGD.::GO:0042866; P:pyruvate biosynthetic process; IDA:RGD.::GO:0009629; P:response to gravity; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0014870; P:response to muscle inactivity; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0043403; P:skeletal muscle tissue regeneration; IDA:RGD.
27	P52480	531	KPYM_MOUSE Pyruvate kinase isozymes M1/M2 OS=...	510	2e-156	463	47	65	GO:0019861; C:flagellum; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004743; F:pyruvate kinase activity; IDA:MGI.
									GO:0006096; P:glycolysis; IDA:MGI.
28	P00548	530	KPYK_CHICK Pyruvate kinase muscle isozyme OS=...	510	3e-156	462	46	65	GO:0005829; C:cytosol; TAS:Reactome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; TAS:Reactome.
29	Q5NVN0	531	KPYM_PONAB Pyruvate kinase isozyme M1 OS=Pong...	510	1e-155	461	46	65	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
30	P11974	531	KPYM_RABIT Pyruvate kinase isozymes M1/M2 OS=...	510	3e-154	457	45	65	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
31	P11979	531	KPYM_FELCA Pyruvate kinase isozyme M1 OS=Feli...	510	6e-153	454	45	64	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030955; F:potassium ion binding; IEA:InterPro.::GO:0004743; F:pyruvate kinase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.

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