FGC: Single Locus Summary

UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOR278W

Length:

275

Number of sequences:

5887

Description:

YOR278W HEM4 SGDID:S000005804, Chr XV from 842817-843644, Genome Release 64-1-1, Verified ORF, "Uroporphyrinogen III synthase, catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in heme biosynthesis; deficiency in the human homolog can result in the disease congenital erythropoietic porphyria"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P06174	275	HEM4_YEAST Uroporphyrinogen-III synthase OS=S...	275	0	561	100	100
									GO:0004852; F:uroporphyrinogen-III synthase activity; IMP:SGD.
									GO:0006783; P:heme biosynthetic process; IMP:SGD.
2	P87214	251	HEM4_SCHPO Uroporphyrinogen-III synthase OS=S...	260	6e-35	131	35	53	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0004852; F:uroporphyrinogen-III synthase activity; ISS:PomBase.
									GO:0006783; P:heme biosynthetic process; ISS:PomBase.
3	P51163	265	HEM4_MOUSE Uroporphyrinogen-III synthase OS=M...	275	0.0000000000004	70.5	26	45	GO:0005739; C:mitochondrion; IDA:MGI.
									GO:0004852; F:uroporphyrinogen-III synthase activity; IDA:MGI.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
4	P10746	265	HEM4_HUMAN Uroporphyrinogen-III synthase OS=H...	280	0.0000000000006	70.1	26	42	GO:0005829; C:cytosol; NAS:UniProtKB.::GO:0005739; C:mitochondrion; ISS:UniProtKB.
									GO:0004852; F:uroporphyrinogen-III synthase activity; IDA:UniProtKB.
									GO:0006783; P:heme biosynthetic process; IDA:UniProtKB.::GO:0006780; P:uroporphyrinogen III biosynthetic process; IDA:UniProtKB.
5	P21248	262	HEM4_BACSU Uroporphyrinogen-III synthase OS=B...	76	0.92	34.3	25	51
									GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:EC.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
6	O67030	448	MNME_AQUAE tRNA modification GTPase MnmE OS=A...	151	0.17	37	26	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006400; P:tRNA modification; IEA:InterPro.
7	B7KI42	428	HEM1_CYAP7 Glutamyl-tRNA reductase OS=29155))...	73	2.7	33.1	30	52
									GO:0008883; F:glutamyl-tRNA reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.
8	Q3IP72	438	PROA_NATPD Gamma-glutamyl phosphate reductase...	56	6.8	32	27	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004350; F:glutamate-5-semialdehyde dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.

records

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Total records:

1 - 8

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