Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR270C
Length:
840
Number of sequences:
5887
Description:
YOR270C VPH1 SGDID:S000005796, Chr XV from 830574-828052, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit a of vacuolar-ATPase V0 domain, one of two isoforms (Vph1p and Stv1p); Vph1p is located in V-ATPase complexes of the vacuole while Stv1p is located in V-ATPase complexes of the Golgi and endosomes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32563    840   VPH1_YEAST V-type proton ATPase subunit a, va...8400     1746     100     100GO:0000329; C:fungal-type vacuole membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IPI:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IMP:UniProtKB.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0016049; P:cell growth; IGI:UniProtKB.::GO:0006797; P:polyphosphate metabolic process; IMP:SGD.::GO:0006461; P:protein complex assembly; IMP:SGD.::GO:0007035; P:vacuolar acidification; IMP:SGD.
2P37296    890   STV1_YEAST V-type proton ATPase subunit a, Go...8910     806     49     64GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005770; C:late endosome; IDA:SGD.::GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IDA:SGD.
GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IGI:SGD.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0007035; P:vacuolar acidification; IGI:SGD.
3Q01290    856   VPH1_NEUCR V-type proton ATPase subunit a OS=...8600     790     46     65GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
4O13742    831   VPH1_SCHPO V-type proton ATPase subunit a OS=...8500     730     46     62GO:0005783; C:endoplasmic reticulum; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; ISS:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; ISS:PomBase.
GO:0015991; P:ATP hydrolysis coupled proton transport; IC:PomBase.::GO:0007035; P:vacuolar acidification; ISS:PomBase.
5Q9Z1G4    839   VPP1_MOUSE V-type proton ATPase 116 kDa subun...8580     639     41     57GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.::GO:0005667; C:transcription factor complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.::GO:0046966; F:thyroid hormone receptor binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0007420; P:brain development; ISS:UniProtKB.::GO:0007507; P:heart development; ISS:UniProtKB.::GO:0030099; P:myeloid cell differentiation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; ISS:UniProtKB.
6P25286    838   VPP1_RAT V-type proton ATPase 116 kDa subunit...8490     637     42     58GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
7Q29466    838   VPP1_BOVIN V-type proton ATPase 116 kDa subun...8490     632     42     58GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
8Q93050    837   VPP1_HUMAN V-type proton ATPase 116 kDa subun...8480     630     42     57GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0051117; F:ATPase binding; IPI:UniProtKB.::GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0033572; P:transferrin transport; TAS:Reactome.
9Q5R422    837   VPP1_PONAB V-type proton ATPase 116 kDa subun...8480     628     41     57GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
10Q8AVM5    831   VPP1_XENLA V-type proton ATPase 116 kDa subun...8460     627     41     57GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
11A1A5G6    837   VPP1_XENTR V-type proton ATPase 116 kDa subun...8480     618     40     57GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
12Q9I8D0    838   VPP1_CHICK V-type proton ATPase 116 kDa subun...8490     616     40     56GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
13Q9HBG4    840   VPP4_HUMAN V-type proton ATPase 116 kDa subun...8450     597     38     58GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0031526; C:brush border membrane; IDA:HGNC.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0051117; F:ATPase binding; IPI:UniProtKB.::GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.::GO:0007588; P:excretion; IMP:HGNC.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0001503; P:ossification; IMP:HGNC.::GO:0006885; P:regulation of pH; IMP:HGNC.::GO:0007605; P:sensory perception of sound; IMP:HGNC.::GO:0033572; P:transferrin transport; TAS:Reactome.
14Q920R6    833   VPP4_MOUSE V-type proton ATPase 116 kDa subun...8490     588     38     57GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.::GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IPI:MGI.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IPI:MGI.
15P30628    905   VPP1_CAEEL Probable V-type proton ATPase 116 ...8950     572     39     55GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0015986; P:ATP synthesis coupled proton transport; NAS:UniProtKB.::GO:0016358; P:dendrite development; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0040013; P:negative regulation of locomotion; NAS:UniProtKB.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0043068; P:positive regulation of programmed cell death; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0001666; P:response to hypoxia; IMP:WormBase.::GO:0007271; P:synaptic transmission, cholinergic; IMP:WormBase.
16Q54E04    815   VATM_DICDI Vacuolar proton translocating ATPa...8330     553     39     57GO:0031164; C:contractile vacuolar membrane; IDA:dictyBase.::GO:0010008; C:endosome membrane; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0030670; C:phagocytic vesicle membrane; IDA:dictyBase.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:dictyBase.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0006911; P:phagocytosis, engulfment; IMP:dictyBase.::GO:0051453; P:regulation of intracellular pH; IMP:dictyBase.
17Q9Y487    856   VPP2_HUMAN V-type proton ATPase 116 kDa subun...8570     550     37     54GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.::GO:0006955; P:immune response; TAS:ProtInc.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0033572; P:transferrin transport; TAS:Reactome.
18O97681    854   VPP2_BOVIN V-type proton ATPase 116 kDa subun...8570     550     37     54GO:0001669; C:acrosomal vesicle; ISS:AgBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
19P15920    856   VPP2_MOUSE V-type proton ATPase 116 kDa subun...8542e-176     538     36     54GO:0001669; C:acrosomal vesicle; IDA:MGI.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
20Q13488    830   VPP3_HUMAN V-type proton ATPase 116 kDa subun...8544e-159     492     36     52GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0033572; P:transferrin transport; TAS:Reactome.
21Q9YEA0    685   VATI_AERPE V-type ATP synthase subunit I OS=1...4503e-17     90.1     24     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
22Q9HM61    637   VATI_THEAC V-type ATP synthase subunit I OS=N...1050.85     37     27     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
23O29106    676   VATI_ARCFU V-type ATP synthase subunit I OS=9...1070.19     38.9     35     44GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.::GO:0004828; F:serine-tRNA ligase activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
24Q9HND8    722   VATI_HALSA V-type ATP synthase subunit I OS=(...600.16     39.3     38     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
25O83544    454   VATI2_TREPA V-type ATP synthase subunit I 2 O...1660.0001     48.9     23     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
26P43439    664   NTPI_ENTHR V-type sodium ATPase subunit I OS=...940.2     38.9     27     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
27O59659    649   VATI_METMA V-type ATP synthase subunit I OS=J...347.9     33.9     44     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
28O57721    659   VATI_PYRHO V-type ATP synthase subunit I OS=N...2580.019     42.4     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
29Q5JDS2    663   VATI_PYRKO V-type ATP synthase subunit I OS=(...1350.002     45.1     30     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
30Q57675    695   VATI_METJA V-type ATP synthase subunit I OS=J...940.018     42.4     31     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
31Q9UWW3    701   VATI_SULSO V-type ATP synthase subunit I OS=P...994.6     34.7     27     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
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