Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR269W
Length:
494
Number of sequences:
5887
Description:
YOR269W PAC1 SGDID:S000005795, Chr XV from 826385-827869, Genome Release 64-1-1, Verified ORF, "Protein involved in nuclear migration, part of the dynein/dynactin pathway; targets dynein to microtubule tips, which is necessary for sliding of microtubules along bud cortex; synthetic lethal with bni1; homolog of human LIS1"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91B4P6P9    411   LIS1_DROYA Lissencephaly-1 homolog OS=Drosoph...1520.11     38.5     21     40GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
92B3NPW0    411   LIS1_DROER Lissencephaly-1 homolog OS=Drosoph...1520.11     38.5     21     40GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
93A1CF18    435   LIS12_ASPCL Nuclear distribution protein nudF...1660.011     42     28     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
94Q17N69    409   LIS1_AEDAE Lissencephaly-1 homolog OS=Aedes a...3903e-33     134     27     48GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
95B7PS00    411   LIS1_IXOSC Lissencephaly-1 homolog OS=Ixodes ...4124e-33     134     28     46GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
96Q00664    444   LIS1_EMENI Nuclear distribution protein nudF ...4215e-33     134     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
97B4KT48    411   LIS1_DROMO Lissencephaly-1 homolog OS=Drosoph...1140.11     38.5     25     42GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
98B3MEY6    411   LIS1_DROAN Lissencephaly-1 homolog OS=Drosoph...1140.093     38.9     26     41GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
99C4Q0P6    417   LIS1_SCHMA Lissencephaly-1 homolog OS=Schisto...3951e-32     132     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
100B3S4I5    409   LIS1_TRIAD Lissencephaly-1 homolog OS=Trichop...3992e-32     131     28     47GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
101C3XVT5    406   LIS1_BRAFL Lissencephaly-1 homolog OS=Branchi...4663e-32     130     27     44GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
102A0DB19    403   LIS11_PARTE Lissencephaly-1 homolog 1 OS=Para...4458e-32     129     28     44GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
103Q0D0X6    446   LIS1_ASPTN Nuclear distribution protein nudF ...4751e-31     129     24     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
104A0CH87    403   LIS12_PARTE Lissencephaly-1 homolog 2 OS=Para...4455e-31     127     27     46GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
105Q2HBX6    454   LIS11_CHAGB Nuclear distribution protein PAC1...5362e-30     126     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
106B8PD53    427   LIS12_POSPM Nuclear distribution protein PAC1...4632e-30     126     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
107B8P4B0    438   LIS11_POSPM Nuclear distribution protein PAC1...1560.000000002     63.2     28     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
108Q9NDC9    404   LIS1_CAEEL Lissencephaly-1 homolog OS=Caenorh...4545e-29     121     27     44GO:0005818; C:aster; IDA:WormBase.::GO:0005938; C:cell cortex; IDA:WormBase.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IDA:WormBase.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:WormBase.
GO:0005515; F:protein binding; IPI:WormBase.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051026; P:chiasma assembly; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0043652; P:engulfment of apoptotic cell; IMP:WormBase.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007018; P:microtubule-based movement; IMP:WormBase.::GO:0007100; P:mitotic centrosome separation; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0035046; P:pronuclear migration; IMP:WormBase.::GO:0051225; P:spindle assembly; IMP:WormBase.::GO:0051932; P:synaptic transmission, GABAergic; IMP:WormBase.::GO:0048489; P:synaptic vesicle transport; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
109A1DP19    441   LIS1_NEOFI Nuclear distribution protein nudF ...4742e-27     117     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
110B6QC06    452   LIS12_PENMQ Nuclear distribution protein nudF...5112e-27     117     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
111A8XZJ9    390   LIS1_CAEBR Lissencephaly-1 homolog OS=Caenorh...4273e-26     113     28     44GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
112P42527    1146   MHCKA_DICDI Myosin heavy chain kinase A OS=Di...850.25     37.7     29     52GO:0005938; C:cell cortex; IDA:dictyBase.
GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0005524; F:ATP binding; IC:dictyBase.::GO:0016887; F:ATPase activity; IDA:dictyBase.::GO:0016905; F:myosin heavy chain kinase activity; IDA:dictyBase.::GO:0045159; F:myosin II binding; IPI:dictyBase.
GO:0051764; P:actin crosslink formation; IDA:dictyBase.::GO:0051017; P:actin filament bundle assembly; IDA:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0031037; P:myosin II filament disassembly; IDA:dictyBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0051260; P:protein homooligomerization; IDA:dictyBase.
113Q8YRI1    1526   YY46_NOSS1 Uncharacterized WD repeat-containi...2040.0000000003     66.6     25     42
114Q93794    587   SEL10_CAEEL F-box/WD repeat-containing protei...950.1     38.9     29     43GO:0030424; C:axon; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:WormBase.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0046660; P:female sex differentiation; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IGI:UniProtKB.
115Q9VZF4    1326   FBXW7_DROME F-box/WD repeat-containing protei...2682e-16     86.3     28     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; NAS:FlyBase.
GO:0030332; F:cyclin binding; TAS:FlyBase.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0008054; P:cyclin catabolic process; TAS:FlyBase.::GO:0042023; P:DNA endoreduplication; IMP:FlyBase.::GO:0060253; P:negative regulation of glial cell proliferation; IGI:FlyBase.::GO:0045926; P:negative regulation of growth; IMP:FlyBase.::GO:0007096; P:regulation of exit from mitosis; TAS:FlyBase.::GO:0007088; P:regulation of mitosis; IMP:FlyBase.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase.
116P87060    775   POP1_SCHPO WD repeat-containing protein pop1 ...1230.44     37     28     45GO:0005634; C:nucleus; IDA:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase.
GO:0030674; F:protein binding, bridging; IPI:PomBase.
GO:0006995; P:cellular response to nitrogen starvation; IGI:PomBase.::GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0008054; P:cyclin catabolic process; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
117D4D8P3    663   SCONB_TRIVH Probable E3 ubiquitin ligase comp...1010.38     37     24     47
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
118D4AM37    663   SCONB_ARTBC Probable E3 ubiquitin ligase comp...940.017     41.6     28     46
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
119Q969H0    707   FBXW7_HUMAN F-box/WD repeat-containing protei...1720.0000004     56.2     26     38GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.::GO:2000346; P:negative regulation of hepatocyte proliferation; ISS:BHF-UCL.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:BHF-UCL.::GO:2000639; P:negative regulation of SREBP-mediated signaling pathway; ISS:BHF-UCL.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0010883; P:regulation of lipid storage; ISS:BHF-UCL.::GO:0032880; P:regulation of protein localization; ISS:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.::GO:0001944; P:vasculature development; TAS:BHF-UCL.
120C5FP68    674   SCONB_ARTOC Probable E3 ubiquitin ligase comp...3160.00000000004     68.9     24     39
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
121Q8VBV4    629   FBXW7_MOUSE F-box/WD repeat-containing protei...1680.000001     55.1     26     39GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0007219; P:Notch signaling pathway; IDA:MGI.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
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