UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOR269W

Length:

494

Number of sequences:

5887

Description:

YOR269W PAC1 SGDID:S000005795, Chr XV from 826385-827869, Genome Release 64-1-1, Verified ORF, "Protein involved in nuclear migration, part of the dynein/dynactin pathway; targets dynein to microtubule tips, which is necessary for sliding of microtubules along bud cortex; synthetic lethal with bni1; homolog of human LIS1"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
211	Q55FR9	1221	COPA_DICDI Coatomer subunit alpha OS=Dictyost...	316	0.00000005	59.7	22	39	GO:0030126; C:COPI vesicle coat; IEA:InterPro.
									GO:0005198; F:structural molecule activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.
212	Q21215	325	GBLP_CAEEL Guanine nucleotide-binding protein...	270	0.0000001	57	26	42	GO:0030424; C:axon; IDA:WormBase.::GO:0044297; C:cell body; IDA:WormBase.::GO:0005813; C:centrosome; IDA:WormBase.::GO:0030426; C:growth cone; IDA:WormBase.::GO:0000776; C:kinetochore; IDA:WormBase.::GO:0005635; C:nuclear envelope; IDA:WormBase.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0048675; P:axon extension; IMP:WormBase.::GO:0051304; P:chromosome separation; IMP:WormBase.::GO:0000281; P:cytokinesis after mitosis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0008045; P:motor axon guidance; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006997; P:nucleus organization; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040038; P:polar body extrusion after meiotic divisions; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0033365; P:protein localization to organelle; IMP:WormBase.::GO:0030334; P:regulation of cell migration; IMP:WormBase.
213	O22785	525	PR19B_ARATH Pre-mRNA-processing factor 19 hom...	164	0.00000007	58.5	30	45	GO:0005618; C:cell wall; IDA:TAIR.::GO:0009507; C:chloroplast; IDA:TAIR.::GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
									GO:0042742; P:defense response to bacterium; IGI:TAIR.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
214	P36408	347	GBB_DICDI Guanine nucleotide-binding protein ...	299	0.00000007	57.8	25	39	GO:0005834; C:heterotrimeric G-protein complex; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
									GO:0031682; F:G-protein gamma-subunit binding; IDA:dictyBase.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
									GO:0007190; P:activation of adenylate cyclase activity; TAS:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; IDA:dictyBase.::GO:0032320; P:positive regulation of Ras GTPase activity; IMP:dictyBase.::GO:0030826; P:regulation of cGMP biosynthetic process; TAS:dictyBase.
215	O18640	318	GBLP_DROME Guanine nucleotide-binding protein...	257	0.00005	48.9	24	43	GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.::GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.
									GO:0042335; P:cuticle development; IMP:FlyBase.::GO:0007626; P:locomotory behavior; IMP:FlyBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0018991; P:oviposition; IMP:FlyBase.::GO:0035220; P:wing disc development; IMP:FlyBase.
216	Q39190	479	PRL2_ARATH Protein pleiotropic regulator PRL2...	124	0.00000009	58.2	31	46	GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.
									GO:0005515; F:protein binding; IPI:TAIR.
217	Q9SJT9	1218	COPA2_ARATH Coatomer subunit alpha-2 OS=Arabi...	174	0.028	40.8	22	36	GO:0030126; C:COPI vesicle coat; IEA:InterPro.::GO:0005829; C:cytosol; IDA:TAIR.
									GO:0005198; F:structural molecule activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
218	Q54Y96	530	SMU1_DICDI WD40 repeat-containing protein smu...	354	0.0000001	57.8	21	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
219	Q15542	800	TAF5_HUMAN Transcription initiation factor TF...	232	0.031	40.8	23	38	GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005669; C:transcription factor TFIID complex; IDA:UniProtKB.::GO:0033276; C:transcription factor TFTC complex; IDA:UniProtKB.
									GO:0046983; F:protein dimerization activity; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
									GO:0016573; P:histone acetylation; IDA:GOC.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.
220	Q23256	501	YH92_CAEEL Uncharacterized WD repeat-containi...	99	0.42	37	26	44
221	A8X8C6	368	TG125_CAEBR WD repeat-containing protein tag-...	106	0.12	38.5	26	48
222	Q9Y263	795	PLAP_HUMAN Phospholipase A-2-activating prote...	260	0.0000001	57.8	25	42
									GO:0016005; F:phospholipase A2 activator activity; TAS:ProtInc.
									GO:0006644; P:phospholipid metabolic process; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
223	Q9USN3	777	UTP13_SCHPO Probable U3 small nucleolar RNA-a...	149	0.058	39.7	23	43	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005732; C:small nucleolar ribonucleoprotein complex; ISS:PomBase.::GO:0032040; C:small-subunit processome; IEA:InterPro.
									GO:0030515; F:snoRNA binding; ISS:PomBase.
									GO:0030490; P:maturation of SSU-rRNA; ISS:PomBase.
224	Q6PBD6	305	WDR61_XENTR WD repeat-containing protein 61 O...	297	0.0000002	56.6	26	42	GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
									GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
225	P54319	795	PLAP_RAT Phospholipase A-2-activating protein...	260	0.0000002	57.4	25	42
226	P38011	319	GBLP_YEAST Guanine nucleotide-binding protein...	266	0.0000002	56.6	23	42	GO:0022627; C:cytosolic small ribosomal subunit; IDA:SGD.
									GO:0001965; F:G-protein alpha-subunit binding; IPI:SGD.::GO:0005092; F:GDP-dissociation inhibitor activity; IDA:SGD.::GO:0004871; F:signal transducer activity; IMP:SGD.
									GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:SGD.::GO:0010255; P:glucose mediated signaling pathway; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0017148; P:negative regulation of translation; IMP:SGD.
227	Q229Z6	634	POC1_TETTS POC1 centriolar protein homolog OS...	214	0.0000002	57	27	39	GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.
									GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0051297; P:centrosome organization; IMP:UniProtKB.
228	Q6GMD2	305	WDR61_XENLA WD repeat-containing protein 61 O...	297	0.0000002	56.2	26	42	GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
									GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
229	Q12788	808	TBL3_HUMAN Transducin beta-like protein 3 OS=...	106	9.7	32.7	25	45	GO:0005730; C:nucleolus; IDA:HPA.::GO:0032040; C:small-subunit processome; IEA:InterPro.
									GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
									GO:0007199; P:G-protein signaling, coupled to cGMP nucleotide second messenger; TAS:ProtInc.::GO:0006364; P:rRNA processing; IEA:InterPro.
230	Q9C4Z6	326	GPLPB_ARATH Guanine nucleotide-binding protei...	234	0.00002	50.1	27	42	GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
									GO:0071215; P:cellular response to abscisic acid stimulus; IEP:TAIR.::GO:0006417; P:regulation of translation; IGI:TAIR.::GO:0042254; P:ribosome biogenesis; IGI:TAIR.::GO:0048364; P:root development; IGI:TAIR.::GO:0009845; P:seed germination; IGI:TAIR.::GO:0048367; P:shoot development; IGI:TAIR.
231	Q58D20	485	NLE1_BOVIN Notchless protein homolog 1 OS=Bos...	102	0.022	40.8	30	55	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
232	Q8C092	801	TAF5_MOUSE Transcription initiation factor TF...	256	0.033	40.4	23	38	GO:0005634; C:nucleus; IDA:MGI.
									GO:0003677; F:DNA binding; IDA:MGI.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
233	Q10281	314	GBLP_SCHPO Guanine nucleotide-binding protein...	270	0.0000004	55.5	23	43	GO:0005737; C:cytoplasm; ISS:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0005080; F:protein kinase C binding; IPI:PomBase.::GO:0043022; F:ribosome binding; IDA:PomBase.
									GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0035556; P:intracellular signal transduction; IMP:PomBase.::GO:2000766; P:negative regulation of cytoplasmic translation; ISS:PomBase.::GO:0031139; P:positive regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0032956; P:regulation of actin cytoskeleton organization; IGI:PomBase.::GO:0032995; P:regulation of fungal-type cell wall biogenesis; IGI:PomBase.
234	P41811	889	COPB2_YEAST Coatomer subunit beta' OS=Sacchar...	214	0.000002	53.9	24	44	GO:0030126; C:COPI vesicle coat; IGI:SGD.
									GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IDA:SGD.
									GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IMP:SGD.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:SGD.
235	P79083	328	EIF3I_SCHPO Eukaryotic translation initiation...	122	0.33	37	25	41	GO:0005829; C:cytosol; IDA:PomBase.::GO:0016282; C:eukaryotic 43S preinitiation complex; IDA:PomBase.::GO:0071540; C:eukaryotic translation initiation factor 3 complex, eIF3e; IDA:PomBase.::GO:0071541; C:eukaryotic translation initiation factor 3 complex, eIF3m; IDA:PomBase.::GO:0034399; C:nuclear periphery; IDA:PomBase.
									GO:0005515; F:protein binding; IPI:PomBase.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
									GO:0065007; P:biological regulation; NAS:PomBase.::GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.
236	Q8VEJ4	485	NLE1_MOUSE Notchless protein homolog 1 OS=Mus...	231	0.00004	49.7	26	39	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0001826; P:inner cell mass cell differentiation; IMP:MGI.::GO:0007219; P:Notch signaling pathway; IDA:MGI.
237	P27612	794	PLAP_MOUSE Phospholipase A-2-activating prote...	248	0.0000005	56.2	25	42
									GO:0016005; F:phospholipase A2 activator activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
									GO:0006954; P:inflammatory response; IDA:MGI.
238	O42249	317	GBLP_ORENI Guanine nucleotide-binding protein...	256	0.14	38.1	23	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
239	P49846	704	TAF5_DROME Transcription initiation factor TF...	81	4.1	33.9	28	44	GO:0000124; C:SAGA complex; IPI:FlyBase.::GO:0005669; C:transcription factor TFIID complex; IDA:FlyBase.
									GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IDA:GOC.
240	Q8BG40	658	KTNB1_MOUSE Katanin p80 WD40-containing subun...	266	0.000003	53.5	24	41	GO:0030424; C:axon; IDA:MGI.::GO:0005813; C:centrosome; IDA:MGI.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0045502; F:dynein binding; IDA:MGI.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
241	O42248	317	GBLP_DANRE Guanine nucleotide-binding protein...	278	1.3	35	24	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0001525; P:angiogenesis; IMP:ZFIN.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; IMP:UniProtKB.::GO:0051302; P:regulation of cell division; IMP:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.::GO:0032880; P:regulation of protein localization; IMP:UniProtKB.

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