Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR269W
Length:
494
Number of sequences:
5887
Description:
YOR269W PAC1 SGDID:S000005795, Chr XV from 826385-827869, Genome Release 64-1-1, Verified ORF, "Protein involved in nuclear migration, part of the dynein/dynactin pathway; targets dynein to microtubule tips, which is necessary for sliding of microtubules along bud cortex; synthetic lethal with bni1; homolog of human LIS1"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q3ULA2    605   FBW1A_MOUSE F-box/WD repeat-containing protei...2270.000000005     62     28     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
152Q4V8C4    328   WDR5B_RAT WD repeat-containing protein 5B OS=...1255.1     33.1     23     48
153P74442    1191   Y143_SYNY3 Uncharacterized WD repeat-containi...2020.00003     50.4     28     39
154Q4R8E7    415   WDR69_MACFA Outer row dynein assembly protein...1551.8     34.7     25     39GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
155Q9V3J8    361   WDS_DROME Protein will die slowly OS=Drosophi...1254.5     33.5     24     43GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IPI:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:FlyBase.
GO:0051568; P:histone H3-K4 methylation; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.
156Q1LV15    415   WDR69_DANRE Outer row dynein assembly protein...2830.00004     49.3     26     37GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.::GO:0060285; P:ciliary cell motility; IMP:UniProtKB.::GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.::GO:0007368; P:determination of left/right symmetry; IMP:UniProtKB.
157Q6P5M2    305   WDR61_DANRE WD repeat-containing protein 61 O...1713.7     33.5     23     43GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
158Q8JZX3    405   POC1A_MOUSE POC1 centriolar protein homolog A...1870.063     39.3     23     40GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.
159Q5RE95    330   WDR5B_PONAB WD repeat-containing protein 5B O...1256     33.1     24     47
160O74855    502   NLE1_SCHPO Ribosome assembly protein C18.05c ...1537     33.1     26     44GO:0005730; C:nucleolus; ISS:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0042254; P:ribosome biogenesis; ISS:PomBase.
161O14170    703   POP2_SCHPO WD repeat-containing protein pop2 ...1010.027     40.8     28     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005635; C:nuclear envelope; IDA:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase.
GO:0030674; F:protein binding, bridging; IPI:PomBase.
GO:0032876; P:negative regulation of DNA endoreduplication; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:PomBase.
162Q5FWQ6    415   WDR69_XENLA Outer row dynein assembly protein...945.7     33.1     26     45GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
163P53699    684   CDC4_CANAX Cell division control protein 4 OS...1783.7     33.9     25     44
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
164Q0P593    415   WDR69_BOVIN Outer row dynein assembly protein...1330.000001     54.3     31     47GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
165Q6P2Y2    415   WDR69_XENTR Outer row dynein assembly protein...1173.7     33.9     24     44GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
166P46800    329   GBLP_DICDI Guanine nucleotide-binding protein...2840.00000000004     67.8     28     43GO:0005813; C:centrosome; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
167P07834    779   CDC4_YEAST Cell division control protein 4 OS...970.007     42.7     28     45GO:0016363; C:nuclear matrix; IDA:SGD.::GO:0043224; C:nuclear SCF ubiquitin ligase complex; IDA:SGD.
GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:SGD.::GO:0007126; P:meiosis; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
168Q9UKB1    542   FBW1B_HUMAN F-box/WD repeat-containing protei...2240.000000006     62     28     42GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; ISS:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
169Q86VZ2    330   WDR5B_HUMAN WD repeat-containing protein 5B O...1256.7     32.7     24     47
170Q5BK30    415   WDR69_RAT Outer row dynein assembly protein 1...1980.0002     47     25     39GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
171Q5SRY7    542   FBW1B_MOUSE F-box/WD repeat-containing protei...2240.000000005     62     28     42GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
172Q54KL5    335   WDR5_DICDI WD repeat-containing protein 5 hom...1250.049     39.7     26     46GO:0035097; C:histone methyltransferase complex; ISS:dictyBase.
GO:0042393; F:histone binding; ISS:dictyBase.
GO:0051568; P:histone H3-K4 methylation; ISS:dictyBase.
173B6GZA1    673   SCONB_PENCW Probable E3 ubiquitin ligase comp...3130.000006     52.4     24     39
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
174Q2KJJ5    800   TBL3_BOVIN Transducin beta-like protein 3 OS=...2400.82     36.2     20     38GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0032040; C:small-subunit processome; IEA:InterPro.
GO:0006364; P:rRNA processing; IEA:InterPro.
175Q9ERF3    305   WDR61_MOUSE WD repeat-containing protein 61 O...3040.0000000006     63.9     29     42GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
176Q86TI4    376   WDR86_HUMAN WD repeat-containing protein 86 O...1010.71     35.8     25     45
177Q8YV57    1683   Y2124_NOSS1 Uncharacterized WD repeat-contain...1630.72     36.6     26     45
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
178Q922V4    513   PLRG1_MOUSE Pleiotropic regulator 1 OS=Mus mu...1810.00004     49.7     24     38GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
179Q9WUC8    514   PLRG1_RAT Pleiotropic regulator 1 OS=Rattus n...2530.015     41.6     23     38GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
180Q2KID6    513   PLRG1_BOVIN Pleiotropic regulator 1 OS=Bos ta...2530.022     40.8     23     38GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
181Q6CKE8    434   PRP46_KLULA Pre-mRNA-splicing factor PRP46 OS...1190.0001     48.1     29     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
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