rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | Q8VBV4 | 629 | FBXW7_MOUSE F-box/WD repeat-containing protei... | 168 | 0.000001 | 55.1 | 26 | 39 | GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI. | | | | | | | | | | GO:0007219; P:Notch signaling pathway; IDA:MGI.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 122 | Q61FW2 | 589 | SEL10_CAEBR F-box/WD repeat-containing protei... | 96 | 1.5 | 35 | 24 | 48 | | | | | | | | | | | | | | | | | | | | | | 123 | Q00808 | 1356 | HETE1_PODAS Vegetative incompatibility protei... | 219 | 0.0000000001 | 67.8 | 29 | 42 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | | 124 | P90648 | 732 | MHCKB_DICDI Myosin heavy chain kinase B OS=Di... | 61 | 0.0003 | 47 | 41 | 52 | GO:0005826; C:actomyosin contractile ring; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0016905; F:myosin heavy chain kinase activity; IDA:dictyBase.::GO:0045159; F:myosin II binding; IPI:dictyBase. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0031037; P:myosin II filament disassembly; IMP:dictyBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase. | 125 | Q8YTC2 | 1258 | Y2800_NOSS1 Uncharacterized WD repeat-contain... | 236 | 0.000000004 | 63.2 | 24 | 44 | | | | | | | | | | | GO:0043531; F:ADP binding; IEA:InterPro. | | | | | | | | | | GO:0006952; P:defense response; IEA:InterPro. | 126 | Q8N136 | 415 | WDR69_HUMAN Outer row dynein assembly protein... | 161 | 0.89 | 35.8 | 24 | 40 | GO:0005929; C:cilium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 127 | Q00659 | 678 | SCONB_EMENI Probable E3 ubiquitin ligase comp... | 131 | 0.002 | 44.7 | 27 | 44 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 128 | Q2UFN8 | 705 | SCONB_ASPOR Probable E3 ubiquitin ligase comp... | 307 | 0.00000000003 | 69.7 | 24 | 39 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 129 | B8NGT5 | 706 | SCONB_ASPFN Probable E3 ubiquitin ligase comp... | 307 | 0.00000000003 | 69.3 | 24 | 39 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 130 | Q0CY32 | 673 | SCONB_ASPTN Probable E3 ubiquitin ligase comp... | 112 | 0.002 | 44.3 | 28 | 46 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 131 | Q5M786 | 334 | WDR5_XENTR WD repeat-containing protein 5 OS=... | 125 | 9.4 | 32.3 | 24 | 47 | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0034968; P:histone lysine methylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 132 | P87053 | 605 | POF1_SCHPO F-box/WD repeat-containing protein... | 153 | 0.9 | 35.8 | 21 | 42 | GO:0000152; C:nuclear ubiquitin ligase complex; ISS:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase. | | | | | | | | | | GO:0030674; F:protein binding, bridging; IPI:PomBase. | | | | | | | | | | GO:0071276; P:cellular response to cadmium ion; IEP:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IPI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase. | 133 | A2QCU8 | 670 | SCONB_ASPNC Probable E3 ubiquitin ligase comp... | 131 | 0.005 | 43.1 | 26 | 45 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 134 | Q9D7H2 | 328 | WDR5B_MOUSE WD repeat-containing protein 5B O... | 125 | 3.4 | 33.9 | 23 | 48 | | | | | | | | | | | | | | | | | | | | | | 135 | Q498M4 | 334 | WDR5_RAT WD repeat-containing protein 5 OS=Ra... | 125 | 6 | 33.1 | 24 | 47 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 136 | P61965 | 334 | WDR5_MOUSE WD repeat-containing protein 5 OS=... | 125 | 6 | 33.1 | 24 | 47 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001501; P:skeletal system development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 137 | P61964 | 334 | WDR5_HUMAN WD repeat-containing protein 5 OS=... | 125 | 6 | 33.1 | 24 | 47 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 138 | A1C7E4 | 700 | SCONB_ASPCL Probable E3 ubiquitin ligase comp... | 309 | 0.00000000003 | 69.7 | 25 | 40 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 139 | Q55563 | 1693 | Y163_SYNY3 Uncharacterized WD repeat-containi... | 297 | 0.0002 | 48.1 | 25 | 41 | | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 140 | Q2KIG2 | 334 | WDR5_BOVIN WD repeat-containing protein 5 OS=... | 125 | 6.1 | 32.7 | 24 | 47 | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 141 | A1DHW6 | 689 | SCONB_NEOFI Probable E3 ubiquitin ligase comp... | 310 | 0.0000000001 | 67.4 | 24 | 40 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 142 | Q01277 | 650 | SCONB_NEUCR Probable E3 ubiquitin ligase comp... | 77 | 1.9 | 34.7 | 29 | 45 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 143 | B6Q4Z5 | 660 | SCONB_PENMQ Probable E3 ubiquitin ligase comp... | 298 | 0.00000000002 | 69.7 | 26 | 41 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 144 | P39014 | 640 | MET30_YEAST F-box protein MET30 OS=Saccharomy... | 74 | 0.005 | 43.1 | 32 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043224; C:nuclear SCF ubiquitin ligase complex; IDA:SGD. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000087; P:M phase of mitotic cell cycle; IMP:SGD.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0000209; P:protein polyubiquitination; IMP:SGD.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.::GO:0000114; P:regulation of transcription involved in G1 phase of mitotic cell cycle; IMP:SGD.::GO:0046685; P:response to arsenic-containing substance; IDA:SGD.::GO:0046686; P:response to cadmium ion; IDA:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 145 | Q09990 | 665 | LIN23_CAEEL F-box/WD repeat-containing protei... | 224 | 0.0000000006 | 65.1 | 28 | 42 | GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0046983; F:protein dimerization activity; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048812; P:neuron projection morphogenesis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase. | 146 | Q9Y297 | 605 | FBW1A_HUMAN F-box/WD repeat-containing protei... | 279 | 0.0000005 | 55.8 | 26 | 39 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0046983; F:protein dimerization activity; IEA:InterPro. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 147 | B8M7Q5 | 667 | SCONB_TALSN Probable E3 ubiquitin ligase comp... | 297 | 0.0000000001 | 67.8 | 26 | 42 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 148 | Q91854 | 518 | TRCB_XENLA Beta-TrCP OS=Xenopus laevis (Afric... | 159 | 0.63 | 36.2 | 24 | 38 | | | | | | | | | | | GO:0046983; F:protein dimerization activity; IEA:InterPro. | | | | | | | | | | GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 149 | Q4X0A9 | 696 | SCONB_ASPFU Probable E3 ubiquitin ligase comp... | 310 | 0.0000000001 | 67.4 | 24 | 40 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 150 | B0XTS1 | 696 | SCONB_ASPFC Probable E3 ubiquitin ligase comp... | 310 | 0.0000000001 | 67.4 | 24 | 40 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 151 | Q3ULA2 | 605 | FBW1A_MOUSE F-box/WD repeat-containing protei... | 227 | 0.000000005 | 62 | 28 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. |