Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR259C
Length:
437
Number of sequences:
5887
Description:
YOR259C RPT4 SGDID:S000005785, Chr XV from 813708-812395, Genome Release 64-1-1, reverse complement, Verified ORF, "One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in degradation of ubiquitinated substrates; contributes preferentially to ERAD; required for spindle pole body duplication; mainly nuclear localization"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q9SSB4    464   PRS7B_ARATH 26S protease regulatory subunit 7...3225e-97     305     48     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
62P85200    414   PRS6B_HELAN 26S protease regulatory subunit 6...3593e-96     302     43     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
63Q9SEI4    408   PRS6B_ARATH 26S protease regulatory subunit 6...3553e-96     301     44     64GO:0005618; C:cell wall; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005634; C:nucleus; TAS:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0000502; C:proteasome complex; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
64Q9SZD4    443   PRS4A_ARATH 26S proteasome regulatory subunit...3823e-96     302     42     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005634; C:nucleus; TAS:TAIR.::GO:0000502; C:proteasome complex; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0007292; P:female gamete generation; IGI:TAIR.::GO:0010386; P:lateral root primordium development; IMP:TAIR.::GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0010078; P:maintenance of root meristem identity; IMP:TAIR.::GO:0048232; P:male gamete generation; IGI:TAIR.::GO:0035266; P:meristem growth; IMP:TAIR.::GO:0009933; P:meristem structural organization; IMP:TAIR.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:TAIR.::GO:0043248; P:proteasome assembly; IMP:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009408; P:response to heat; IMP:TAIR.::GO:0051788; P:response to misfolded protein; IMP:TAIR.::GO:0048829; P:root cap development; IMP:TAIR.::GO:0090351; P:seedling development; IMP:TAIR.
65P46507    415   PRS6B_MANSE 26S protease regulatory subunit 6...3555e-96     301     44     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
66P62193    440   PRS4_RAT 26S protease regulatory subunit 4 OS...3825e-96     302     42     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:RGD.
GO:0030163; P:protein catabolic process; IEA:InterPro.
67P62192    440   PRS4_MOUSE 26S protease regulatory subunit 4 ...3825e-96     302     42     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
68P62191    440   PRS4_HUMAN 26S protease regulatory subunit 4 ...3825e-96     302     42     62GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; NAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
69Q9SL67    443   PRS4B_ARATH 26S proteasome regulatory subunit...3825e-96     302     42     63GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0000502; C:proteasome complex; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0007292; P:female gamete generation; IGI:TAIR.::GO:0010078; P:maintenance of root meristem identity; IMP:TAIR.::GO:0048232; P:male gamete generation; IGI:TAIR.::GO:0030163; P:protein catabolic process; IEA:InterPro.
70P48601    439   PRS4_DROME 26S protease regulatory subunit 4 ...3927e-96     301     41     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:FlyBase.::GO:0004175; F:endopeptidase activity; IDA:FlyBase.
GO:0008283; P:cell proliferation; IMP:FlyBase.::GO:0000022; P:mitotic spindle elongation; IMP:FlyBase.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IDA:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.
71D4GUJ7    406   PAN1_HALVD Proteasome-activating nucleotidase...3611e-95     300     44     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
72P34124    403   PRS8_DICDI 26S protease regulatory subunit 8 ...3581e-95     300     44     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005838; C:proteasome regulatory particle; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004175; F:endopeptidase activity; ISS:dictyBase.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; ISS:dictyBase.
73P33299    467   PRS7_YEAST 26S protease regulatory subunit 7 ...3222e-95     301     47     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008540; C:proteasome regulatory particle, base subcomplex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0045732; P:positive regulation of protein catabolic process; IDA:SGD.::GO:0045899; P:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; IMP:SGD.::GO:0070682; P:proteasome regulatory particle assembly; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IPI:SGD.
74Q63570    418   PRS6B_RAT 26S protease regulatory subunit 6B ...3553e-95     299     44     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:RGD.
GO:0030163; P:protein catabolic process; IEA:InterPro.
75P54775    418   PRS6B_MOUSE 26S protease regulatory subunit 6...3553e-95     299     44     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0001824; P:blastocyst development; IMP:MGI.::GO:0030163; P:protein catabolic process; IEA:InterPro.
76Q4R7L3    418   PRS6B_MACFA 26S protease regulatory subunit 6...3554e-95     299     44     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
77P43686    418   PRS6B_HUMAN 26S protease regulatory subunit 6...3554e-95     299     44     64GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
78Q3T030    418   PRS6B_BOVIN 26S protease regulatory subunit 6...3554e-95     299     44     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
79Q4R4R0    433   PRS7_MACFA 26S protease regulatory subunit 7 ...3204e-95     299     47     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
80P35998    433   PRS7_HUMAN 26S protease regulatory subunit 7 ...3204e-95     299     47     64GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
81Q5E9F9    433   PRS7_BOVIN 26S protease regulatory subunit 7 ...3204e-95     299     47     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
82P46471    433   PRS7_MOUSE 26S protease regulatory subunit 7 ...3204e-95     299     47     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
83Q90732    440   PRS4_CHICK 26S protease regulatory subunit 4 ...3824e-95     300     41     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
84Q63347    433   PRS7_RAT 26S protease regulatory subunit 7 OS...3205e-95     299     47     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
85Q86JA1    428   PRS7_DICDI 26S protease regulatory subunit 7 ...3205e-95     299     47     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
86P46472    433   PRS7_XENLA 26S protease regulatory subunit 7 ...3207e-95     299     47     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
87Q5R8D7    433   PRS7_PONAB 26S protease regulatory subunit 7 ...3203e-94     297     47     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
88P41836    403   PRS8_SCHPO 26S protease regulatory subunit 8 ...3703e-94     296     44     63GO:0005829; C:cytosol; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.::GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0004175; F:endopeptidase activity; ISS:PomBase.
GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:PomBase.
89Q18787    435   PRS7_CAEEL 26S protease regulatory subunit 7 ...3203e-94     297     46     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
90Q55BV5    439   PRS4_DICDI 26S protease regulatory subunit 4 ...3182e-92     292     45     67GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase.
91P34123    403   PRS6B_DICDI 26S protease regulatory subunit 6...3463e-92     291     44     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005838; C:proteasome regulatory particle; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004175; F:endopeptidase activity; ISS:dictyBase.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006972; P:hyperosmotic response; IEP:dictyBase.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; ISS:dictyBase.
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