UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOR254C

Length:

663

Number of sequences:

5887

Description:

YOR254C SEC63 SGDID:S000005780, Chr XV from 807023-805032, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
511	B2SQU3	376	DNAJ_XANOP Chaperone protein DnaJ OS=Xanthomo...	73	0.0000003	56.6	37	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
512	Q2P458	376	DNAJ_XANOM Chaperone protein DnaJ OS=Xanthomo...	73	0.0000003	56.6	37	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
513	D3ZD82	199	DNJ5B_RAT DnaJ homolog subfamily C member 5B ...	120	0.0000003	54.7	33	47	GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
514	Q3BVB7	375	DNAJ_XANC5 Chaperone protein DnaJ OS=Xanthomo...	73	0.0000003	56.6	37	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
515	Q9HHB8	384	DNAJ_HALME Chaperone protein DnaJ OS=Halofera...	73	0.0000003	56.6	44	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
516	A5EYE5	374	DNAJ_DICNV Chaperone protein DnaJ OS=Dichelob...	72	0.0000003	56.6	44	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
517	Q5BIP8	348	DNJB5_BOVIN DnaJ homolog subfamily B member 5...	72	0.0000003	56.6	40	65
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
518	B1YKT0	368	DNAJ_EXIS2 Chaperone protein DnaJ OS=Exiguoba...	78	0.0000003	56.6	40	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
519	O75953	348	DNJB5_HUMAN DnaJ homolog subfamily B member 5...	72	0.0000003	56.2	40	65
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.::GO:0006986; P:response to unfolded protein; IEP:UniProtKB.
520	Q8EB99	262	DJLA_SHEON DnaJ-like protein DjlA OS=Shewanel...	67	0.0000003	55.8	42	60	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0051087; F:chaperone binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
521	A7I2G3	359	DNAJ_CAMHC Chaperone protein DnaJ OS=CH001A)....	72	0.0000003	56.6	42	65	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
522	Q0WTI8	184	DNJ72_ARATH Chaperone protein dnaJ 72 OS=Arab...	90	0.0000003	54.3	31	61	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
523	P71500	372	DNAJ_MYCCT Chaperone protein DnaJ OS=27343 / ...	73	0.0000003	56.6	42	67	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
524	Q96EY1	480	DNJA3_HUMAN DnaJ homolog subfamily A member 3...	72	0.0000004	56.6	40	63	GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IDA:UniProtKB.::GO:0042645; C:mitochondrial nucleoid; IDA:UniProtKB.::GO:0031594; C:neuromuscular junction; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0005133; F:interferon-gamma receptor binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
									GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0060336; P:negative regulation of interferon-gamma-mediated signaling pathway; IDA:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007528; P:neuromuscular junction development; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0050821; P:protein stabilization; IDA:UniProtKB.::GO:0009408; P:response to heat; IEA:InterPro.::GO:0034341; P:response to interferon-gamma; IDA:UniProtKB.::GO:0071340; P:skeletal muscle acetylcholine-gated channel clustering; ISS:UniProtKB.
525	Q21H37	374	DNAJ_SACD2 Chaperone protein DnaJ OS=Saccharo...	73	0.0000004	56.2	40	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
526	P77866	375	DNAJ_AGGAC Chaperone protein DnaJ OS=actinomy...	73	0.0000004	56.2	44	67	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
527	P48353	224	HLJ1_YEAST Protein HLJ1 OS=Saccharomyces cere...	97	0.0000004	55.1	37	51	GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.
									GO:0001671; F:ATPase activator activity; IDA:SGD.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.::GO:0006457; P:protein folding; IEA:InterPro.
528	Q72GN6	350	DNAJ_THET2 Chaperone protein DnaJ OS=Thermus ...	78	0.0000004	56.2	41	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
529	B3WEQ6	387	DNAJ_LACCB Chaperone protein DnaJ OS=Lactobac...	77	0.0000004	56.2	40	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
530	Q038N5	387	DNAJ_LACC3 Chaperone protein DnaJ OS=Lactobac...	77	0.0000004	56.2	40	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
531	Q5SLW9	350	DNAJ1_THET8 Chaperone protein DnaJ 1 OS=Therm...	78	0.0000004	56.2	41	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
532	Q9CQ94	199	DNJ5B_MOUSE DnaJ homolog subfamily C member 5...	120	0.0000004	54.3	33	47	GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
533	Q8VXV4	436	DNJ16_ARATH Chaperone protein dnaJ 16 OS=Arab...	81	0.0000005	56.2	40	63	GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.
534	Q8DWH2	377	DNAJ_STRMU Chaperone protein DnaJ OS=Streptoc...	70	0.0000005	56.2	41	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
535	B1LZ52	380	DNAJ_METRJ Chaperone protein DnaJ OS=2831). G...	73	0.0000005	56.2	37	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
536	Q04960	413	DNJH_CUCSA DnaJ protein homolog OS=Cucumis sa...	70	0.0000005	56.2	44	61	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
537	F1RTY8	199	DNJ5B_PIG DnaJ homolog subfamily C member 5B ...	70	0.0000005	54.3	44	59	GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
538	B1ZUS0	382	DNAJ_OPITP Chaperone protein DnaJ OS=Opitutus...	71	0.0000005	55.8	42	59	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
539	B2GBQ6	386	DNAJ_LACF3 Chaperone protein DnaJ OS=Lactobac...	72	0.0000005	55.8	38	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
540	Q6LV37	277	DJLA_PHOPR DnaJ-like protein DjlA OS=Photobac...	66	0.0000005	55.5	39	64	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0051087; F:chaperone binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
541	B6IZJ1	374	DNAJ_COXB2 Chaperone protein DnaJ OS=Q212)). ...	73	0.0000005	55.8	36	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.

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