Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR249C
Length:
685
Number of sequences:
5887
Description:
YOR249C APC5 SGDID:S000005775, Chr XV from 800731-798674, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the platform domain of the APC/C, based on structural analysis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q08683    685   APC5_YEAST Anaphase-promoting complex subunit...6850     1401     100     100GO:0005680; C:anaphase-promoting complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0031497; P:chromatin assembly; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016567; P:protein ubiquitination; IDA:GOC.
2Q9P4W7    744   APC5_SCHPO Anaphase-promoting complex subunit...1920.00006     50.1     24     45GO:0005680; C:anaphase-promoting complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IC:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IC:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016567; P:protein ubiquitination; IC:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IC:PomBase.
3Q8H1U4    916   APC5_ARATH Anaphase-promoting complex subunit...890.04     40.8     30     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
4Q7UZK6    455   CLPX_PROMP ATP-dependent Clp protease ATP-bin...1770.049     40.4     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
5Q5ZKK3    756   APC5_CHICK Anaphase-promoting complex subunit...1081.5     35.8     30     45GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0005488; F:binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
6Q9JMI0    775   ECEL1_MOUSE Endothelin-converting enzyme-like...2252.1     35.4     19     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IDA:MGI.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
7Q5RE52    755   APC5_PONAB Anaphase-promoting complex subunit...1082.5     35     30     44GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
8Q9UJX4    755   APC5_HUMAN Anaphase-promoting complex subunit...1082.5     35     30     44GO:0005680; C:anaphase-promoting complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:ProtInc.::GO:0000090; P:mitotic anaphase; TAS:ProtInc.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
9O95672    775   ECEL1_HUMAN Endothelin-converting enzyme-like...2252.5     35     19     41GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007218; P:neuropeptide signaling pathway; TAS:ProtInc.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
10Q9JHL3    775   ECEL1_RAT Endothelin-converting enzyme-like 1...2694.7     34.3     19     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IDA:GOC.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; TAS:RGD.
GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0007218; P:neuropeptide signaling pathway; IDA:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
11Q8BTZ4    740   APC5_MOUSE Anaphase-promoting complex subunit...985.6     33.9     28     43GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
12A1L1K3    727   APC5_RAT Anaphase-promoting complex subunit 5...985.7     33.9     28     43GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
13A2BZ43    455   CLPX_PROM5 ATP-dependent Clp protease ATP-bin...1776.4     33.5     22     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
14P49467    843   RPOC1_ODOSI DNA-directed RNA polymerase subun...866.5     33.9     24     45GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
15Q74NJ4    113   RS17_NANEQ 30S ribosomal protein S17P OS=Nano...606.5     31.6     22     55GO:0005840; C:ribosome; IEA:UniProtKB-KW.
GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
16Q9USW4    519   YHZ9_SCHPO Uncharacterized protein C21B10.09 ...1386.6     33.5     24     43GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008521; F:acetyl-CoA transporter activity; ISS:PomBase.::GO:0022857; F:transmembrane transporter activity; NAS:PomBase.
GO:0035348; P:acetyl-CoA transmembrane transport; ISS:PomBase.
17Q12019    4910   MDN1_YEAST Midasin OS=Saccharomyces cerevisia...1547.9     33.5     23     50GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005654; C:nucleoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0006461; P:protein complex assembly; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0000027; P:ribosomal large subunit assembly; IMP:SGD.::GO:0006364; P:rRNA processing; IMP:SGD.
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