rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q5V3R2 | 185 | DYR1_HALMA Dihydrofolate reductase 1 OS=B-180... | 60 | 0.046 | 37.4 | 27 | 58 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0009165; P:nucleotide biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 92 | P27422 | 157 | DYR7_ECOLX Dihydrofolate reductase type 7 OS=... | 128 | 0.087 | 36.2 | 25 | 45 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0009165; P:nucleotide biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.::GO:0031427; P:response to methotrexate; IEA:UniProtKB-KW. | 93 | Q9GLN7 | 1304 | ACE_PANTR Angiotensin-converting enzyme OS=Pa... | 137 | 0.091 | 37.4 | 22 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008241; F:peptidyl-dipeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 94 | P12821 | 1306 | ACE_HUMAN Angiotensin-converting enzyme OS=Ho... | 137 | 0.093 | 37.4 | 22 | 44 | GO:0005768; C:endosome; IDA:BHF-UCL.::GO:0009897; C:external side of plasma membrane; IDA:BHF-UCL.::GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0005624; C:membrane fraction; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0031711; F:bradykinin receptor binding; IPI:BHF-UCL.::GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0031404; F:chloride ion binding; IDA:BHF-UCL.::GO:0008144; F:drug binding; IDA:BHF-UCL.::GO:0004175; F:endopeptidase activity; IDA:UniProtKB.::GO:0008237; F:metallopeptidase activity; IEA:InterPro.::GO:0008241; F:peptidyl-dipeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:BHF-UCL. | | | | | | | | | | GO:0002005; P:angiotensin catabolic process in blood; IC:UniProtKB.::GO:0050482; P:arachidonic acid secretion; IDA:BHF-UCL.::GO:0001974; P:blood vessel remodeling; IC:BHF-UCL.::GO:0060218; P:hemopoietic stem cell differentiation; IC:BHF-UCL.::GO:0042447; P:hormone catabolic process; IDA:BHF-UCL.::GO:0001822; P:kidney development; IMP:BHF-UCL.::GO:0032943; P:mononuclear cell proliferation; IC:BHF-UCL.::GO:0043171; P:peptide catabolic process; IDA:BHF-UCL.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0002019; P:regulation of renal output by angiotensin; IC:BHF-UCL.::GO:0014910; P:regulation of smooth muscle cell migration; ISS:BHF-UCL.::GO:0019229; P:regulation of vasoconstriction; IC:UniProtKB.::GO:0042312; P:regulation of vasodilation; IC:BHF-UCL. | 95 | P04382 | 193 | DYR_BPT4 Dihydrofolate reductase OS=Enterobac... | 158 | 0.15 | 35.8 | 25 | 46 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0009165; P:nucleotide biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.::GO:0031427; P:response to methotrexate; IEA:UniProtKB-KW. | 96 | Q04515 | 187 | DYR10_ECOLX Dihydrofolate reductase type A10 ... | 113 | 0.24 | 35 | 28 | 49 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0009165; P:nucleotide biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.::GO:0031427; P:response to methotrexate; IEA:UniProtKB-KW. | 97 | A7MVH5 | 391 | PURT_VIBHB Phosphoribosylglycinamide formyltr... | 97 | 0.55 | 34.7 | 28 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro. | | | | | | | | | | GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro. | 98 | Q87Q53 | 391 | PURT_VIBPA Phosphoribosylglycinamide formyltr... | 92 | 0.8 | 33.9 | 30 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro. | | | | | | | | | | GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro. | 99 | P12822 | 1310 | ACE_RABIT Angiotensin-converting enzyme OS=Or... | 86 | 1.1 | 33.9 | 23 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008241; F:peptidyl-dipeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 100 | Q7MK47 | 391 | PURT_VIBVY Phosphoribosylglycinamide formyltr... | 97 | 2.9 | 32.3 | 29 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro. | | | | | | | | | | GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro. | 101 | Q8DA32 | 391 | PURT_VIBVU Phosphoribosylglycinamide formyltr... | 97 | 2.9 | 32.3 | 29 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro. | | | | | | | | | | GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro. | 102 | P04051 | 1460 | RPC1_YEAST DNA-directed RNA polymerase III su... | 166 | 7 | 31.2 | 25 | 43 | GO:0005666; C:DNA-directed RNA polymerase III complex; IDA:SGD. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0032549; F:ribonucleoside binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0042797; P:tRNA transcription from RNA polymerase III promoter; IDA:SGD. |