Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR233W
Length:
800
Number of sequences:
5887
Description:
YOR233W KIN4 SGDID:S000005759, Chr XV from 775846-778248, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase that inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271Q91820    407   AURAA_XENLA Aurora kinase A-A OS=Xenopus laev...2826e-35     142     29     50GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0000922; C:spindle pole; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; IMP:UniProtKB.
272Q9Z1M4    485   KS6B2_MOUSE Ribosomal protein S6 kinase beta-...2846e-35     143     31     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
273B4LDJ6    781   PLK4_DROVI Serine/threonine-protein kinase PL...2747e-35     146     31     51GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
274P06244    397   KAPA_YEAST cAMP-dependent protein kinase type...2747e-35     142     33     55GO:0005952; C:cAMP-dependent protein kinase complex; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007265; P:Ras protein signal transduction; IMP:SGD.
275Q5BKK4    418   SGK1_XENTR Serine/threonine-protein kinase Sg...3061e-34     141     32     50GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
276Q15831    433   STK11_HUMAN Serine/threonine-protein kinase S...3041e-34     141     32     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016020; C:membrane; ISS:UniProtKB.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0030295; F:protein kinase activator activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0043276; P:anoikis; IMP:BHF-UCL.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0042304; P:regulation of fatty acid biosynthetic process; TAS:Reactome.::GO:0046320; P:regulation of fatty acid oxidation; TAS:Reactome.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; IDA:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0001944; P:vasculature development; ISS:UniProtKB.
277Q9DG02    475   KCC2D_XENLA Calcium/calmodulin-dependent prot...2761e-34     142     34     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
278Q91819    408   AURAB_XENLA Aurora kinase A-B OS=Xenopus laev...2821e-34     141     29     51GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005876; C:spindle microtubule; ISS:UniProtKB.::GO:0000922; C:spindle pole; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019894; F:kinesin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; ISS:UniProtKB.
279O88831    587   KKCC2_RAT Calcium/calmodulin-dependent protei...2962e-34     143     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.::GO:0030295; F:protein kinase activator activity; TAS:RGD.
GO:0032147; P:activation of protein kinase activity; IDA:RGD.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
280Q5F3L1    789   KS6A5_CHICK Ribosomal protein S6 kinase alpha...2715e-33     140     34     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
281P62343    524   CDPK1_PLAFK Calcium-dependent protein kinase ...2812e-34     142     35     54GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
282P62344    524   CDPK1_PLAF7 Calcium-dependent protein kinase ...2812e-34     142     35     54GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
283Q6U1I9    432   SGK1_CHICK Serine/threonine-protein kinase Sg...2952e-34     141     33     51GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
284A0AUV4    508   SMKY_MOUSE Sperm motility kinase Y OS=Mus mus...2762e-34     142     31     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
285Q8C078    588   KKCC2_MOUSE Calcium/calmodulin-dependent prot...2962e-34     142     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
286P97477    395   AURKA_MOUSE Aurora kinase A OS=Mus musculus (...2992e-34     140     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:MGI.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
287P28582    532   CDPK_DAUCA Calcium-dependent protein kinase O...2763e-34     142     33     55GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
288Q9C6P3    521   CDPKX_ARATH Calcium-dependent protein kinase ...2733e-34     141     34     54GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
289Q54MH0    749   FHKD_DICDI Probable serine/threonine-protein ...2823e-34     144     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000077; P:DNA damage checkpoint; ISS:dictyBase.
290Q6VZ17    626   HUNKB_XENLA Hormonally up-regulated neu tumor...2204e-34     142     37     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
291Q9FMP5    528   CDPKH_ARATH Calcium-dependent protein kinase ...2734e-34     141     33     55GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0080092; P:regulation of pollen tube growth; IMP:TAIR.
292Q4KTY1    415   KPSH1_PINFU Serine/threonine-protein kinase H...2764e-34     140     33     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
293P90980    682   KPC2_CAEEL Protein kinase C-like 2 OS=Caenorh...2564e-34     143     33     55GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0043005; C:neuron projection; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
294O77708    533   KCC2D_RABIT Calcium/calmodulin-dependent prot...2784e-34     141     32     50GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB.
295P27466    446   KCC1_YEAST Calcium/calmodulin-dependent prote...2074e-34     140     35     56GO:0005737; C:cytoplasm; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:SGD.
GO:0007165; P:signal transduction; IMP:SGD.
296Q9Z2B9    773   KS6A4_MOUSE Ribosomal protein S6 kinase alpha...2742e-22     106     31     52GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0048273; F:mitogen-activated protein kinase p38 binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0043987; P:histone H3-S10 phosphorylation; ISS:UniProtKB.::GO:0043988; P:histone H3-S28 phosphorylation; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.
297Q8C050    863   KS6A5_MOUSE Ribosomal protein S6 kinase alpha...1955e-27     121     35     58GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0043990; P:histone H2A-S1 phosphorylation; ISS:UniProtKB.::GO:0043987; P:histone H3-S10 phosphorylation; ISS:UniProtKB.::GO:0043988; P:histone H3-S28 phosphorylation; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.
298O70126    345   AURKB_MOUSE Aurora kinase B OS=Mus musculus (...2695e-34     138     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
299P07334    593   CDR1_SCHPO Mitosis inducer protein kinase cdr...2795e-34     141     34     51GO:0005829; C:cytosol; IDA:PomBase.::GO:0071341; C:medial cortical node; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IGI:PomBase.::GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; TAS:PomBase.::GO:0071574; P:protein localization to medial cortex; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.::GO:0007089; P:traversing start control point of mitotic cell cycle; NAS:PomBase.
300P22517    447   KCC2_YEAST Calcium/calmodulin-dependent prote...2105e-34     140     37     57GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:SGD.
GO:0007165; P:signal transduction; NAS:SGD.
301P16912    583   KDC2_DROME Protein kinase DC2 OS=Drosophila m...2755e-34     141     32     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.
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