rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | Q8C015 | 719 | PAK7_MOUSE Serine/threonine-protein kinase PA... | 272 | 9e-30 | 127 | 30 | 53 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 212 | Q3UTQ8 | 938 | CDKL5_MOUSE Cyclin-dependent kinase-like 5 OS... | 221 | 9e-30 | 127 | 33 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 213 | Q4WHP3 | 815 | STE20_ASPFU Serine/threonine-protein kinase s... | 269 | 9e-30 | 127 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 214 | D4A280 | 718 | PAK7_RAT Serine/threonine-protein kinase PAK ... | 272 | 1e-29 | 127 | 30 | 53 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 215 | O76039 | 1030 | CDKL5_HUMAN Cyclin-dependent kinase-like 5 OS... | 221 | 1e-29 | 127 | 33 | 54 | GO:0032839; C:dendrite cytoplasm; ISS:BHF-UCL.::GO:0044294; C:dendritic growth cone; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:HGNC. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:HGNC.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0048365; F:Rac GTPase binding; ISS:BHF-UCL. | | | | | | | | | | GO:0001764; P:neuron migration; ISS:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; ISS:BHF-UCL.::GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:BHF-UCL.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:HGNC. | 216 | Q8BPM2 | 847 | M4K5_MOUSE Mitogen-activated protein kinase k... | 277 | 1e-29 | 127 | 31 | 52 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB. | 217 | Q9Y2U5 | 619 | M3K2_HUMAN Mitogen-activated protein kinase k... | 217 | 1e-29 | 126 | 35 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB. | 218 | P97820 | 1233 | M4K4_MOUSE Mitogen-activated protein kinase k... | 310 | 1e-29 | 127 | 32 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB.::GO:0006950; P:response to stress; IDA:UniProtKB. | 219 | Q2ULU3 | 848 | STE20_ASPOR Serine/threonine-protein kinase s... | 269 | 1e-29 | 126 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 220 | Q62925 | 1493 | M3K1_RAT Mitogen-activated protein kinase kin... | 274 | 2e-29 | 127 | 30 | 50 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008432; F:JUN kinase binding; IPI:RGD.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:RGD.::GO:0004710; F:MAPK/ERK kinase kinase activity; IDA:RGD.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:RGD.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:RGD.::GO:0046625; F:sphingolipid binding; IPI:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032232; P:negative regulation of actin filament bundle assembly; IDA:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0050434; P:positive regulation of viral transcription; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0051259; P:protein oligomerization; IDA:RGD.::GO:0000209; P:protein polyubiquitination; IMP:RGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IGI:RGD.::GO:0006970; P:response to osmotic stress; IMP:RGD. | 221 | Q9Y4K4 | 846 | M4K5_HUMAN Mitogen-activated protein kinase k... | 277 | 2e-29 | 126 | 31 | 52 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc. | 222 | Q91820 | 407 | AURAA_XENLA Aurora kinase A-A OS=Xenopus laev... | 271 | 2e-29 | 123 | 32 | 48 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0000922; C:spindle pole; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; IMP:UniProtKB. | 223 | Q99683 | 1374 | M3K5_HUMAN Mitogen-activated protein kinase k... | 297 | 2e-29 | 127 | 35 | 52 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0070301; P:cellular response to hydrogen peroxide; IDA:BHF-UCL.::GO:0010421; P:hydrogen peroxide-mediated programmed cell death; IDA:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0008631; P:induction of apoptosis by oxidative stress; IDA:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 224 | P23647 | 805 | FUSED_DROME Serine/threonine-protein kinase f... | 278 | 2e-29 | 126 | 28 | 50 | GO:0035301; C:Hedgehog signaling complex; IPI:FlyBase.::GO:0016020; C:membrane; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:FlyBase. | | | | | | | | | | GO:0007293; P:germarium-derived egg chamber formation; IMP:FlyBase.::GO:0007228; P:positive regulation of hh target transcription factor activity; IMP:FlyBase.::GO:0042993; P:positive regulation of transcription factor import into nucleus; IMP:FlyBase.::GO:0031647; P:regulation of protein stability; IDA:FlyBase.::GO:0030162; P:regulation of proteolysis; NAS:FlyBase.::GO:0007367; P:segment polarity determination; IMP:FlyBase. | 225 | Q13233 | 1512 | M3K1_HUMAN Mitogen-activated protein kinase k... | 274 | 2e-29 | 126 | 30 | 50 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome. | 226 | P53349 | 1493 | M3K1_MOUSE Mitogen-activated protein kinase k... | 274 | 2e-29 | 126 | 30 | 50 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IDA:BHF-UCL. | 227 | O35099 | 1380 | M3K5_MOUSE Mitogen-activated protein kinase k... | 297 | 3e-29 | 126 | 35 | 52 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; IDA:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 228 | Q54TN4 | 715 | MKCE_DICDI Probable serine/threonine-protein ... | 263 | 3e-29 | 125 | 29 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 229 | Q6YY75 | 534 | NEK6_ORYSJ Serine/threonine-protein kinase Ne... | 271 | 4e-29 | 124 | 29 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 230 | Q7ZYJ0 | 1001 | TAO1B_XENLA Serine/threonine-protein kinase T... | 268 | 4e-29 | 125 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB. | 231 | O22042 | 651 | M3K3_ARATH Mitogen-activated protein kinase k... | 280 | 4e-29 | 124 | 31 | 51 | GO:0048046; C:apoplast; IDA:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC. | | | | | | | | | | GO:0043622; P:cortical microtubule organization; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:TAIR. | 232 | Q6NW76 | 320 | AURKB_DANRE Aurora kinase B OS=Danio rerio (Z... | 269 | 4e-29 | 120 | 30 | 47 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007059; P:chromosome segregation; IMP:ZFIN.::GO:0000910; P:cytokinesis; IMP:ZFIN.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 233 | Q8R9T6 | 625 | PKN1_THETN Probable serine/threonine-protein ... | 214 | 5e-29 | 124 | 36 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 234 | Q7Z2Y5 | 1582 | NRK_HUMAN Nik-related protein kinase OS=Homo ... | 251 | 5e-29 | 125 | 31 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | | 235 | Q4P5N0 | 746 | STE20_USTMA Serine/threonine-protein kinase S... | 273 | 6e-29 | 124 | 33 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 236 | Q7L7X3 | 1001 | TAOK1_HUMAN Serine/threonine-protein kinase T... | 268 | 6e-29 | 125 | 33 | 53 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB. | 237 | O22040 | 666 | ANP1_ARATH Mitogen-activated protein kinase k... | 286 | 6e-29 | 124 | 29 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC. | | | | | | | | | | GO:0009908; P:flower development; IGI:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0006979; P:response to oxidative stress; IDA:TAIR. | 238 | Q55FT4 | 2247 | TSUA_DICDI Probable serine/threonine-protein ... | 275 | 6e-29 | 125 | 29 | 49 | GO:0005881; C:cytoplasmic microtubule; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0030010; P:establishment of cell polarity; IMP:dictyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0031272; P:regulation of pseudopodium assembly; IMP:dictyBase. | 239 | Q5F2E8 | 1001 | TAOK1_MOUSE Serine/threonine-protein kinase T... | 268 | 7e-29 | 124 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB. | 240 | O88664 | 1001 | TAOK1_RAT Serine/threonine-protein kinase TAO... | 268 | 7e-29 | 124 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030295; F:protein kinase activator activity; IMP:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; IDA:UniProtKB. | 241 | Q7Z8E9 | 914 | STE20_MAGO7 Serine/threonine-protein kinase M... | 267 | 8e-29 | 124 | 33 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. |