Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR212W
Length:
423
Number of sequences:
5887
Description:
YOR212W STE4 SGDID:S000005738, Chr XV from 742910-744181, Genome Release 64-1-1, Verified ORF, "G protein beta subunit, forms a dimer with Ste18p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste18p to dampen signaling; may recruit Rho1p to the polarized growth site during mating; contains WD40 repeats"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q5RE95    330   WDR5B_PONAB WD repeat-containing protein 5B O...3220.000000002     62.4     22     42
122Q86VZ2    330   WDR5B_HUMAN WD repeat-containing protein 5B O...3220.000000001     63.2     22     42
123Q92636    917   FAN_HUMAN Protein FAN OS=Homo sapiens (Human)...3430.0000000004     65.5     22     40GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
GO:0006672; P:ceramide metabolic process; TAS:ProtInc.
124Q9C270    899   PWP2_NEUCR Periodic tryptophan protein 2 homo...2691.9     34.7     20     36
125O88879    1249   APAF_MOUSE Apoptotic protease-activating fact...1240.0002     47.8     23     45GO:0005634; C:nucleus; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.
GO:0043531; F:ADP binding; IEA:InterPro.::GO:0016505; F:apoptotic protease activator activity; IPI:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:MGI.
GO:0006952; P:defense response; IEA:InterPro.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; IGI:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0051402; P:neuron apoptotic process; IGI:MGI.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
126Q8N0X2    631   SPG16_HUMAN Sperm-associated antigen 16 prote...3200.00005     49.3     23     36GO:0035085; C:cilium axoneme; ISS:UniProtKB.::GO:0035086; C:flagellar axoneme; IEA:UniProtKB-SubCell.
GO:0042384; P:cilium assembly; ISS:UniProtKB.
127B5X3C4    410   LIS1B_SALSA Lissencephaly-1 homolog B OS=Salm...2380.002     43.9     22     42GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
128Q9V3J8    361   WDS_DROME Protein will die slowly OS=Drosophi...3530.0000000008     63.5     21     39GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IPI:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:FlyBase.
GO:0051568; P:histone H3-K4 methylation; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.
129Q9LV28    326   GPLPC_ARATH Guanine nucleotide-binding protei...2570.00004     48.9     24     40GO:0005730; C:nucleolus; IDA:TAIR.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0071215; P:cellular response to abscisic acid stimulus; IEP:TAIR.::GO:0048364; P:root development; IGI:TAIR.::GO:0048367; P:shoot development; IGI:TAIR.
130Q9EPV5    1249   APAF_RAT Apoptotic protease-activating factor...3320.006     42.7     22     37GO:0043293; C:apoptosome; IDA:RGD.
GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IPI:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.
GO:0007568; P:aging; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0010659; P:cardiac muscle cell apoptotic process; IMP:RGD.::GO:0030154; P:cell differentiation; IEP:RGD.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:RGD.::GO:0006952; P:defense response; IEA:InterPro.::GO:0034349; P:glial cell apoptotic process; IEP:RGD.::GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0051260; P:protein homooligomerization; IDA:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.
131Q25306    312   GBLP_LEIMA Guanine nucleotide-binding protein...2610.22     37     21     41
132O76734    579   TUP1_DICDI General transcriptional corepresso...1270.046     39.7     27     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
133Q229Z6    634   POC1_TETTS POC1 centriolar protein homolog OS...1820.044     39.7     20     36GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.
GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0051297; P:centrosome organization; IMP:UniProtKB.
134Q93847    395   YZLL_CAEEL Uncharacterized WD repeat-containi...621.8     34.3     31     50
135Q5FVN8    476   WSDU1_RAT WD repeat, SAM and U-box domain-con...2540.4     36.6     23     39GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
136Q01369    316   GBLP_NEUCR Guanine nucleotide-binding protein...2080.052     39.3     21     38
137Q4RJN5    410   LIS1_TETNG Lissencephaly-1 homolog OS=nigrovi...2380.002     43.9     21     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
138Q7ZUV2    694   KTNB1_DANRE Katanin p80 WD40-containing subun...2100.00000004     58.9     23     45GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
139P62884    312   GBLP_LEIIN Guanine nucleotide-binding protein...1651.8     34.3     22     40
140P62883    312   GBLP_LEICH Guanine nucleotide-binding protein...1651.8     34.3     22     40
141O42249    317   GBLP_ORENI Guanine nucleotide-binding protein...2590.003     42.7     21     37GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
142O24076    325   GBLP_MEDSA Guanine nucleotide-binding protein...1202.9     33.5     23     40
143Q5ZIU8    657   KTNB1_CHICK Katanin p80 WD40-containing subun...2770.000003     53.1     21     38GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
144Q91854    518   TRCB_XENLA Beta-TrCP OS=Xenopus laevis (Afric...438.1     32.3     37     58
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
145P25635    923   PWP2_YEAST Periodic tryptophan protein 2 OS=S...2240.012     41.6     19     39GO:0005737; C:cytoplasm; IDA:SGD.::GO:0034388; C:Pwp2p-containing subcomplex of 90S preribosome; IDA:SGD.::GO:0032040; C:small-subunit processome; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0030515; F:snoRNA binding; IPI:SGD.
GO:0000910; P:cytokinesis; IMP:SGD.::GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0030010; P:establishment of cell polarity; IMP:SGD.
146Q9UUG8    598   TUP12_SCHPO Transcriptional repressor tup12 O...2650.000008     51.6     22     40GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0042393; F:histone binding; IDA:PomBase.::GO:0003714; F:transcription corepressor activity; IDA:PomBase.
GO:0043156; P:chromatin remodeling in response to cation stress; IMP:PomBase.::GO:0006342; P:chromatin silencing; IMP:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
147Q10281    314   GBLP_SCHPO Guanine nucleotide-binding protein...2510.53     35.8     20     36GO:0005737; C:cytoplasm; ISS:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005080; F:protein kinase C binding; IPI:PomBase.::GO:0043022; F:ribosome binding; IDA:PomBase.
GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0035556; P:intracellular signal transduction; IMP:PomBase.::GO:2000766; P:negative regulation of cytoplasmic translation; ISS:PomBase.::GO:0031139; P:positive regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0032956; P:regulation of actin cytoskeleton organization; IGI:PomBase.::GO:0032995; P:regulation of fungal-type cell wall biogenesis; IGI:PomBase.
148Q3ULA2    605   FBW1A_MOUSE F-box/WD repeat-containing protei...2360.00004     49.7     22     41GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
149Q6NZH4    410   LIS1_XENTR Lissencephaly-1 homolog OS=Xenopus...2380.003     43.1     21     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
150Q9D994    303   WDR38_MOUSE WD repeat-containing protein 38 O...2060.0001     47.4     24     43
151Q9Y297    605   FBW1A_HUMAN F-box/WD repeat-containing protei...436.2     32.7     37     58GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
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