Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR208W
Length:
750
Number of sequences:
5887
Description:
YOR208W PTP2 SGDID:S000005734, Chr XV from 733925-736177, Genome Release 64-1-1, Verified ORF, "Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the nucleus"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91E9Q612    1226   PTPRO_MOUSE Receptor-type tyrosine-protein ph...840.000003     54.7     37     56GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0043197; C:dendritic spine; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016328; C:lateral plasma membrane; IDA:UniProtKB.
GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0017147; F:Wnt-protein binding; IDA:UniProtKB.
GO:0007411; P:axon guidance; IMP:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; IMP:UniProtKB.::GO:0030032; P:lamellipodium assembly; IMP:UniProtKB.::GO:0002548; P:monocyte chemotaxis; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0003105; P:negative regulation of glomerular filtration; ISS:UniProtKB.::GO:0036060; P:slit diaphragm assembly; IMP:UniProtKB.
92P54830    541   PTN5_MOUSE Tyrosine-protein phosphatase non-r...3270.0000000009     65.5     23     37GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IMP:MGI.
93P35992    1631   PTP10_DROME Tyrosine-protein phosphatase 10D ...1200.00000001     62.4     37     46GO:0045177; C:apical part of cell; IDA:FlyBase.::GO:0030424; C:axon; IDA:FlyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IDA:FlyBase.
GO:0007417; P:central nervous system development; IGI:FlyBase.::GO:0007616; P:long-term memory; IMP:FlyBase.::GO:0008045; P:motor axon guidance; IGI:FlyBase.::GO:0007424; P:open tracheal system development; IGI:FlyBase.
94Q9W0G1    548   PTP61_DROME Tyrosine-protein phosphatase non-...3240.000000002     64.3     24     39GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005740; C:mitochondrial envelope; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:FlyBase.
GO:0007411; P:axon guidance; IPI:FlyBase.::GO:0071456; P:cellular response to hypoxia; IMP:FlyBase.::GO:0007377; P:germ-band extension; IDA:UniProtKB.::GO:0000278; P:mitotic cell cycle; IMP:FlyBase.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:FlyBase.::GO:0032880; P:regulation of protein localization; IDA:FlyBase.::GO:0031647; P:regulation of protein stability; IMP:FlyBase.
95Q6YI48    1434   PTPRU_CHICK Receptor-type tyrosine-protein ph...2770.064     40.4     23     35GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
96B2RU80    1998   PTPRB_MOUSE Receptor-type tyrosine-protein ph...850.000002     55.1     34     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0001525; P:angiogenesis; IDA:UniProtKB.
97Q12923    2485   PTN13_HUMAN Tyrosine-protein phosphatase non-...800.0000003     57.8     39     53GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
98Q06180    406   PTN2_MOUSE Tyrosine-protein phosphatase non-r...3260.00000001     61.6     24     37GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.
99P35233    416   PTN2_RAT Tyrosine-protein phosphatase non-rec...3260.00000002     60.5     23     37GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; TAS:RGD.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:RGD.
100Q9IBD8    1216   PTPRC_CYPCA Receptor-type tyrosine-protein ph...2840.0009     46.6     22     36GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0050852; P:T cell receptor signaling pathway; IEA:InterPro.
101Q5I141    300   PTPJ1_MDBVW Tyrosine phosphatase-like protein...2750.00000006     58.5     24     40
GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
102P23467    1997   PTPRB_HUMAN Receptor-type tyrosine-protein ph...940.000003     54.7     33     49GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
103Q16849    979   PTPRN_HUMAN Receptor-type tyrosine-protein ph...1330.0000004     57.4     29     46GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB.
104Q63259    983   PTPRN_RAT Receptor-type tyrosine-protein phos...710.051     40.8     30     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD.
GO:0051020; F:GTPase binding; IPI:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0019221; P:cytokine-mediated signaling pathway; IDA:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0019932; P:second-messenger-mediated signaling; TAS:RGD.
105P56722    979   PTPRN_BOVIN Receptor-type tyrosine-protein ph...710.047     40.8     30     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.
106P49445    359   PTN7_RAT Tyrosine-protein phosphatase non-rec...840.0001     48.9     36     45GO:0005829; C:cytosol; IDA:RGD.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
107Q60673    979   PTPRN_MOUSE Receptor-type tyrosine-protein ph...710.052     40.8     30     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; TAS:MGI.::GO:0005886; C:plasma membrane; TAS:MGI.
GO:0004725; F:protein tyrosine phosphatase activity; TAS:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:MGI.
108P54829    565   PTN5_HUMAN Tyrosine-protein phosphatase non-r...1060.005     43.9     26     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:UniProtKB.
GO:0001784; F:phosphotyrosine binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:UniProtKB.
109Q9HD43    1115   PTPRH_HUMAN Receptor-type tyrosine-protein ph...900.00003     51.6     32     47GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
110P35236    360   PTN7_HUMAN Tyrosine-protein phosphatase non-r...840.002     44.7     32     43GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
111Q8ISC9    555   CSW_DROSI Tyrosine-protein phosphatase corksc...970.000003     54.3     35     48GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007362; P:terminal region determination; ISS:UniProtKB.::GO:0008293; P:torso signaling pathway; ISS:UniProtKB.
112P29349    845   CSW_DROME Tyrosine-protein phosphatase corksc...650.095     40     37     48GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:FlyBase.::GO:0004728; F:receptor signaling protein tyrosine phosphatase activity; NAS:FlyBase.
GO:0008069; P:dorsal/ventral axis specification, ovarian follicular epithelium; IMP:FlyBase.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IMP:FlyBase.::GO:0007427; P:epithelial cell migration, open tracheal system; IMP:FlyBase.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; IMP:FlyBase.::GO:0007444; P:imaginal disc development; IMP:FlyBase.::GO:0007498; P:mesoderm development; IMP:FlyBase.::GO:0000278; P:mitotic cell cycle; IMP:FlyBase.::GO:0007428; P:primary branching, open tracheal system; TAS:FlyBase.::GO:0045314; P:regulation of compound eye photoreceptor development; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; TAS:FlyBase.::GO:0007362; P:terminal region determination; IMP:UniProtKB.::GO:0008293; P:torso signaling pathway; IGI:UniProtKB.::GO:0007418; P:ventral midline development; IMP:FlyBase.
113Q8BUM3    359   PTN7_MOUSE Tyrosine-protein phosphatase non-r...840.00007     49.3     36     45
GO:0004725; F:protein tyrosine phosphatase activity; TAS:MGI.
114Q64512    2453   PTN13_MOUSE Tyrosine-protein phosphatase non-...800.00003     51.6     38     53GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
115B3DK56    1444   PTPRU_DANRE Receptor-type tyrosine-protein ph...1320.13     39.7     27     40GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001757; P:somite specification; IMP:ZFIN.
116Q24708    764   CSW_DROVI Tyrosine-protein phosphatase corksc...450.64     37.4     38     51GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007362; P:terminal region determination; ISS:UniProtKB.::GO:0008293; P:torso signaling pathway; ISS:UniProtKB.
117P17706    415   PTN2_HUMAN Tyrosine-protein phosphatase non-r...780.05     40.4     31     50GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
118Q5I145    320   PTPH3_MDBVW Tyrosine phosphatase H3 OS=Microp...1180.032     40.8     29     46
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.
119O02695    1013   PTPR2_MACNE Receptor-type tyrosine-protein ph...710.0008     46.6     34     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
120Q92932    1015   PTPR2_HUMAN Receptor-type tyrosine-protein ph...710.001     46.2     34     52GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
121Q9H3S7    1636   PTN23_HUMAN Tyrosine-protein phosphatase non-...780.0008     47     31     51GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.
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