Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR208W
Length:
750
Number of sequences:
5887
Description:
YOR208W PTP2 SGDID:S000005734, Chr XV from 733925-736177, Genome Release 64-1-1, Verified ORF, "Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the nucleus"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P06800    1291   PTPRC_MOUSE Receptor-type tyrosine-protein ph...3790.0000000001     68.9     24     41GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
GO:0043395; F:heparan sulfate proteoglycan binding; IDA:MGI.::GO:0008201; F:heparin binding; IDA:MGI.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
GO:0000187; P:activation of MAPK activity; IMP:MGI.::GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0042100; P:B cell proliferation; IMP:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0034113; P:heterotypic cell-cell adhesion; IMP:MGI.::GO:0007159; P:leukocyte cell-cell adhesion; IMP:MGI.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IDA:UniProtKB.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0031953; P:negative regulation of protein autophosphorylation; IMP:MGI.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; IMP:UniProtKB.::GO:0045060; P:negative thymic T cell selection; IMP:MGI.::GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IMP:MGI.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0030890; P:positive regulation of B cell proliferation; IMP:MGI.::GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IMP:MGI.::GO:0002925; P:positive regulation of humoral immune response mediated by circulating immunoglobulin; IMP:MGI.::GO:0048304; P:positive regulation of isotype switching to IgG isotypes; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IMP:MGI.::GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IMP:MGI.::GO:0045059; P:positive thymic T cell selection; IMP:MGI.::GO:0045577; P:regulation of B cell differentiation; IMP:MGI.::GO:0050855; P:regulation of B cell receptor signaling pathway; IMP:MGI.::GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0042098; P:T cell proliferation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
32Q62130    1189   PTN14_MOUSE Tyrosine-protein phosphatase non-...3291e-18     94.7     25     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0001946; P:lymphangiogenesis; IMP:UniProtKB.
33Q9W6V5    1406   PTPRJ_CHICK Receptor-type tyrosine-protein ph...3452e-18     94.4     27     41GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB.
34Q62136    1176   PTN21_MOUSE Tyrosine-protein phosphatase non-...3292e-18     94     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
35Q64605    1907   PTPRS_RAT Receptor-type tyrosine-protein phos...3344e-17     90.1     26     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
36B0V2N1    1907   PTPRS_MOUSE Receptor-type tyrosine-protein ph...3344e-17     90.1     26     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0021549; P:cerebellum development; IMP:MGI.::GO:0021987; P:cerebral cortex development; IMP:MGI.::GO:0022038; P:corpus callosum development; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0021510; P:spinal cord development; IMP:MGI.
37Q03348    796   PTPRA_RAT Receptor-type tyrosine-protein phos...1370.002     45.4     29     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:RGD.
GO:0032403; F:protein complex binding; IDA:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.
GO:0048709; P:oligodendrocyte differentiation; IEP:RGD.::GO:0048714; P:positive regulation of oligodendrocyte differentiation; IMP:RGD.::GO:0006468; P:protein phosphorylation; IEA:InterPro.
38Q05209    780   PTN12_HUMAN Tyrosine-protein phosphatase non-...3483e-18     92.8     26     41GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
39Q9UMZ3    2332   PTPRQ_HUMAN Phosphotidylinositol phosphatase ...3504e-18     93.2     28     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0045598; P:regulation of fat cell differentiation; IDA:UniProtKB.
40O88488    2302   PTPRQ_RAT Phosphotidylinositol phosphatase PT...3295e-18     93.2     28     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0045598; P:regulation of fat cell differentiation; ISS:UniProtKB.
41Q62728    1175   PTN21_RAT Tyrosine-protein phosphatase non-re...3295e-18     92.8     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.
GO:0007010; P:cytoskeleton organization; NAS:RGD.
42P32587    303   PYP3_SCHPO Tyrosine-protein phosphatase 3 OS=...3285e-18     89.4     27     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004725; F:protein tyrosine phosphatase activity; IDA:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.
43Q16827    1216   PTPRO_HUMAN Receptor-type tyrosine-protein ph...3376e-18     92.4     27     40GO:0016324; C:apical plasma membrane; ISS:UniProtKB.::GO:0030424; C:axon; ISS:UniProtKB.::GO:0043197; C:dendritic spine; ISS:UniProtKB.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0016021; C:integral to membrane; TAS:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0016328; C:lateral plasma membrane; ISS:UniProtKB.
GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB.::GO:0017147; F:Wnt-protein binding; ISS:UniProtKB.
GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.::GO:0002548; P:monocyte chemotaxis; IMP:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0010812; P:negative regulation of cell-substrate adhesion; ISS:UniProtKB.::GO:0003105; P:negative regulation of glomerular filtration; ISS:UniProtKB.::GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.::GO:0090260; P:negative regulation of retinal ganglion cell axon guidance; ISS:UniProtKB.::GO:0036060; P:slit diaphragm assembly; ISS:UniProtKB.
44P32586    711   PYP2_SCHPO Tyrosine-protein phosphatase 2 OS=...3306e-18     92     26     39GO:0005829; C:cytosol; IDA:PomBase.::GO:0005739; C:mitochondrion; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; IGI:PomBase.::GO:0045835; P:negative regulation of meiosis; IMP:PomBase.::GO:0051403; P:stress-activated MAPK cascade; IGI:PomBase.
45Q62656    2316   PTPRZ_RAT Receptor-type tyrosine-protein phos...1210.031     41.6     26     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
46P29352    802   PTN22_MOUSE Tyrosine-protein phosphatase non-...3321e-17     91.3     28     39GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL.
GO:0019900; F:kinase binding; IPI:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
GO:0050868; P:negative regulation of T cell activation; IMP:BHF-UCL.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:UniProtKB.::GO:0035644; P:phosphoanandamide dephosphorylation; IDA:BHF-UCL.::GO:0032817; P:regulation of natural killer cell proliferation; ISS:BHF-UCL.::GO:0030217; P:T cell differentiation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:MGI.
47P25044    335   PTP1_YEAST Tyrosine-protein phosphatase 1 OS=...3451e-17     88.6     26     40GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:SGD.
GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.
48P54637    990   PTP3_DICDI Tyrosine-protein phosphatase 3 OS=...3311e-17     91.3     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007243; P:intracellular protein kinase cascade; IMP:dictyBase.::GO:0034504; P:protein localization to nucleus; IMP:dictyBase.::GO:0006970; P:response to osmotic stress; IMP:dictyBase.::GO:0042501; P:serine phosphorylation of STAT protein; IMP:dictyBase.
49Q16825    1174   PTN21_HUMAN Tyrosine-protein phosphatase non-...3292e-17     90.9     23     40GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; TAS:ProtInc.
GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
50P0C5E4    2300   PTPRQ_MOUSE Phosphotidylinositol phosphatase ...3292e-17     91.3     28     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0045598; P:regulation of fat cell differentiation; ISS:UniProtKB.
51P23471    2315   PTPRZ_HUMAN Receptor-type tyrosine-protein ph...1210.032     41.6     26     45GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0008330; F:protein tyrosine/threonine phosphatase activity; NAS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0007417; P:central nervous system development; TAS:ProtInc.
52P70289    1705   PTPRV_MOUSE Receptor-type tyrosine-protein ph...3413e-17     90.5     27     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
53P28827    1452   PTPRM_HUMAN Receptor-type tyrosine-protein ph...2750.00005     50.8     22     37GO:0005913; C:cell-cell adherens junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0045296; F:cadherin binding; IDA:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:UniProtKB.
GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; IMP:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:UniProtKB.::GO:0042493; P:response to drug; IDA:UniProtKB.::GO:0010842; P:retina layer formation; IMP:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; IDA:UniProtKB.
54P16621    2029   LAR_DROME Tyrosine-protein phosphatase Lar OS...3370.000000000000009     82.4     25     36GO:0030424; C:axon; IDA:FlyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0004725; F:protein tyrosine phosphatase activity; IDA:FlyBase.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0032093; F:SAM domain binding; IPI:FlyBase.
GO:0007412; P:axon target recognition; IMP:FlyBase.::GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; NAS:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0008594; P:photoreceptor cell morphogenesis; IMP:FlyBase.::GO:0045467; P:R7 cell development; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:FlyBase.::GO:0051124; P:synaptic growth at neuromuscular junction; IMP:FlyBase.
55P28828    1452   PTPRM_MOUSE Receptor-type tyrosine-protein ph...2750.0002     48.9     22     37GO:0005913; C:cell-cell adherens junction; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0045296; F:cadherin binding; ISS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB.
GO:0007156; P:homophilic cell adhesion; ISS:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0045909; P:positive regulation of vasodilation; IMP:MGI.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; ISS:UniProtKB.
56P81718    613   PTN6_RAT Tyrosine-protein phosphatase non-rec...3441e-16     87.8     27     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046703; F:natural killer cell lectin-like receptor binding; IPI:RGD.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0009611; P:response to wounding; IEP:RGD.
57P28192    1159   PTP2_CAEEL Tyrosine-protein phosphatase 2 OS=...3321e-16     88.6     26     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
58P29351    595   PTN6_MOUSE Tyrosine-protein phosphatase non-r...3442e-16     87     27     40GO:0042105; C:alpha-beta T cell receptor complex; IDA:MGI.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0001784; F:phosphotyrosine binding; IPI:MGI.::GO:0042169; F:SH2 domain binding; IDA:MGI.::GO:0017124; F:SH3 domain binding; IDA:MGI.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB.
GO:0050853; P:B cell receptor signaling pathway; IMP:MGI.::GO:0030154; P:cell differentiation; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:MGI.::GO:0035556; P:intracellular signal transduction; IDA:MGI.::GO:0042267; P:natural killer cell mediated cytotoxicity; IMP:MGI.::GO:0002924; P:negative regulation of humoral immune response mediated by circulating immunoglobulin; IMP:MGI.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:MGI.::GO:0043409; P:negative regulation of MAPK cascade; IMP:MGI.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0042130; P:negative regulation of T cell proliferation; IMP:MGI.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IMP:MGI.::GO:0045577; P:regulation of B cell differentiation; IMP:MGI.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
59Q15262    1439   PTPRK_HUMAN Receptor-type tyrosine-protein ph...2830.00007     50.1     24     39GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0031256; C:leading edge membrane; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB.
GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0010839; P:negative regulation of keratinocyte proliferation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
60P35822    1457   PTPRK_MOUSE Receptor-type tyrosine-protein ph...2830.00007     50.1     24     39GO:0030424; C:axon; IDA:MGI.::GO:0030425; C:dendrite; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0001750; C:photoreceptor outer segment; IDA:MGI.
GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
61P26045    913   PTN3_HUMAN Tyrosine-protein phosphatase non-r...3374e-16     86.7     26     40GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.
GO:0051117; F:ATPase binding; IPI:BHF-UCL.::GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IPI:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
GO:0051045; P:negative regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:BHF-UCL.
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