Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR208W
Length:
750
Number of sequences:
5887
Description:
YOR208W PTP2 SGDID:S000005734, Chr XV from 733925-736177, Genome Release 64-1-1, Verified ORF, "Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the nucleus"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P29461    750   PTP2_YEAST Tyrosine-protein phosphatase 2 OS=...7500     1526     100     100GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004725; F:protein tyrosine phosphatase activity; IDA:SGD.
GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IGI:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:0043937; P:regulation of sporulation; IGI:SGD.
2O55082    426   PTN20_MOUSE Tyrosine-protein phosphatase non-...3479e-23     105     27     40GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
3A1L1L3    421   PTN20_RAT Tyrosine-protein phosphatase non-re...3501e-22     105     27     41GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
4Q61152    453   PTN18_MOUSE Tyrosine-protein phosphatase non-...3371e-21     102     27     40GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
5P23469    700   PTPRE_HUMAN Receptor-type tyrosine-protein ph...2760.00000000001     71.6     27     39GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.
6Q64604    1898   PTPRF_RAT Receptor-type tyrosine-protein phos...3342e-16     88.2     25     37GO:0005768; C:endosome; IDA:RGD.::GO:0060076; C:excitatory synapse; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.
GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0042301; F:phosphate ion binding; IDA:RGD.::GO:0030971; F:receptor tyrosine kinase binding; IPI:RGD.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:RGD.
GO:0007156; P:homophilic cell adhesion; IDA:RGD.::GO:0031345; P:negative regulation of cell projection organization; IMP:RGD.::GO:0008285; P:negative regulation of cell proliferation; IMP:RGD.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IMP:RGD.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:RGD.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:RGD.::GO:0051387; P:negative regulation of nerve growth factor receptor signaling pathway; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0050803; P:regulation of synapse structure and activity; IMP:RGD.
7A4IFW2    1909   PTPRF_DANRE Receptor-type tyrosine-protein ph...3340.000000000000002     84.3     25     36GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
8Q98936    1422   PTPRG_CHICK Receptor-type tyrosine-protein ph...1190.014     42.7     29     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
9Q13332    1948   PTPRS_HUMAN Receptor-type tyrosine-protein ph...3342e-17     90.9     25     37GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
10Q05909    1442   PTPRG_MOUSE Receptor-type tyrosine-protein ph...1180.0008     47     30     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
11Q64487    1912   PTPRD_MOUSE Receptor-type tyrosine-protein ph...3345e-17     89.7     26     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
12P23468    1912   PTPRD_HUMAN Receptor-type tyrosine-protein ph...3340.000000000000001     85.1     25     36GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc.
13A2A8L5    1898   PTPRF_MOUSE Receptor-type tyrosine-protein ph...3342e-16     88.2     25     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
14P23470    1445   PTPRG_HUMAN Receptor-type tyrosine-protein ph...1180.0008     46.6     30     46GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
15A7MBJ4    1898   PTPRF_BOVIN Receptor-type tyrosine-protein ph...3342e-16     88.2     25     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
16Q9Y2R2    807   PTN22_HUMAN Tyrosine-protein phosphatase non-...3496e-20     98.6     28     42GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0019900; F:kinase binding; ISS:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; ISS:BHF-UCL.
GO:0050868; P:negative regulation of T cell activation; IMP:BHF-UCL.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0035644; P:phosphoanandamide dephosphorylation; ISS:BHF-UCL.::GO:0050855; P:regulation of B cell receptor signaling pathway; NAS:BHF-UCL.::GO:0045088; P:regulation of innate immune response; IC:BHF-UCL.::GO:0032817; P:regulation of natural killer cell proliferation; IDA:BHF-UCL.::GO:0030217; P:T cell differentiation; ISS:BHF-UCL.
17Q4JDL3    420   PTN20_HUMAN Tyrosine-protein phosphatase non-...3266e-20     96.7     27     40GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
18P49446    699   PTPRE_MOUSE Receptor-type tyrosine-protein ph...810.011     42.7     30     57GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.
GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.::GO:0033003; P:regulation of mast cell activation; IMP:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; IDA:MGI.
19B2GV87    699   PTPRE_RAT Receptor-type tyrosine-protein phos...2770.0000000006     66.2     25     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; NAS:RGD.
GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.
20Q12913    1337   PTPRJ_HUMAN Receptor-type tyrosine-protein ph...3382e-19     97.4     28     40GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0070097; F:delta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IPI:UniProtKB.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:UniProtKB.::GO:0005161; F:platelet-derived growth factor receptor binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
GO:0060242; P:contact inhibition; NAS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.::GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0043116; P:negative regulation of vascular permeability; IDA:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0050918; P:positive chemotaxis; IDA:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; IMP:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0045885; P:positive regulation of survival gene product expression; IDA:UniProtKB.
21P10586    1907   PTPRF_HUMAN Receptor-type tyrosine-protein ph...3342e-16     88.2     25     37GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc.
22Q99952    460   PTN18_HUMAN Tyrosine-protein phosphatase non-...3472e-19     95.5     26     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.
23Q64455    1238   PTPRJ_MOUSE Receptor-type tyrosine-protein ph...3363e-19     96.7     28     40GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032587; C:ruffle membrane; IDA:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IMP:UniProtKB.
GO:0007596; P:blood coagulation; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:MGI.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.::GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:2000272; P:negative regulation of receptor activity; IMP:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0010759; P:positive regulation of macrophage chemotaxis; IDA:UniProtKB.::GO:0010572; P:positive regulation of platelet activation; IMP:UniProtKB.::GO:0001570; P:vasculogenesis; IMP:MGI.
24Q15678    1187   PTN14_HUMAN Tyrosine-protein phosphatase non-...3295e-19     96.3     25     40GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
GO:0001946; P:lymphangiogenesis; IMP:UniProtKB.
25P18433    802   PTPRA_HUMAN Receptor-type tyrosine-protein ph...3330.0000000002     67.8     24     37GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006468; P:protein phosphorylation; IEA:InterPro.
26P35831    775   PTN12_MOUSE Tyrosine-protein phosphatase non-...3487e-19     95.1     27     41GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:MGI.::GO:0002102; C:podosome; IDA:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
27P35832    1301   PTP99_DROME Tyrosine-protein phosphatase 99A ...1140.023     42     31     46GO:0030424; C:axon; IDA:FlyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; ISS:FlyBase.
GO:0007415; P:defasciculation of motor neuron axon; IGI:FlyBase.::GO:0008045; P:motor axon guidance; IGI:FlyBase.
28P04157    1273   PTPRC_RAT Receptor-type tyrosine-protein phos...3800.000000000009     72.4     25     42GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0009898; C:internal side of plasma membrane; TAS:RGD.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0019887; F:protein kinase regulator activity; TAS:RGD.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:RGD.
GO:0042100; P:B cell proliferation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; ISS:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; ISS:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; ISS:UniProtKB.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; ISS:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; IDA:RGD.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
29Q9BMN8    2200   LAR_CAEEL Tyrosine-protein phosphatase Lar-li...2810.00000007     60.1     24     36GO:0005912; C:adherens junction; IMP:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IDA:WormBase.
GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0010172; P:embryonic body morphogenesis; IMP:UniProtKB.::GO:0008544; P:epidermis development; IMP:WormBase.::GO:0007369; P:gastrulation; IMP:WormBase.::GO:0007399; P:nervous system development; IMP:UniProtKB.::GO:0000003; P:reproduction; IMP:WormBase.
30P08575    1304   PTPRC_HUMAN Receptor-type tyrosine-protein ph...3781e-16     88.6     26     43GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0042100; P:B cell proliferation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0048539; P:bone marrow development; IMP:UniProtKB.::GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0002244; P:hemopoietic progenitor cell differentiation; IMP:UniProtKB.::GO:0002378; P:immunoglobulin biosynthetic process; IMP:UniProtKB.::GO:0006933; P:negative regulation of cell adhesion involved in substrate-bound cell migration; IMP:UniProtKB.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; ISS:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; ISS:UniProtKB.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; ISS:UniProtKB.::GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.::GO:2000473; P:positive regulation of hematopoietic stem cell migration; IMP:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; NAS:UniProtKB.::GO:2000648; P:positive regulation of stem cell proliferation; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; ISS:UniProtKB.::GO:0033261; P:regulation of S phase; IMP:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0048864; P:stem cell development; IMP:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.
31P06800    1291   PTPRC_MOUSE Receptor-type tyrosine-protein ph...3790.0000000001     68.9     24     41GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
GO:0043395; F:heparan sulfate proteoglycan binding; IDA:MGI.::GO:0008201; F:heparin binding; IDA:MGI.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
GO:0000187; P:activation of MAPK activity; IMP:MGI.::GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0042100; P:B cell proliferation; IMP:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0034113; P:heterotypic cell-cell adhesion; IMP:MGI.::GO:0007159; P:leukocyte cell-cell adhesion; IMP:MGI.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IDA:UniProtKB.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0031953; P:negative regulation of protein autophosphorylation; IMP:MGI.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; IMP:UniProtKB.::GO:0045060; P:negative thymic T cell selection; IMP:MGI.::GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IMP:MGI.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0030890; P:positive regulation of B cell proliferation; IMP:MGI.::GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IMP:MGI.::GO:0002925; P:positive regulation of humoral immune response mediated by circulating immunoglobulin; IMP:MGI.::GO:0048304; P:positive regulation of isotype switching to IgG isotypes; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IMP:MGI.::GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IMP:MGI.::GO:0045059; P:positive thymic T cell selection; IMP:MGI.::GO:0045577; P:regulation of B cell differentiation; IMP:MGI.::GO:0050855; P:regulation of B cell receptor signaling pathway; IMP:MGI.::GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0042098; P:T cell proliferation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
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