Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR185C
Length:
220
Number of sequences:
5887
Description:
YOR185C GSP2 SGDID:S000005711, Chr XV from 682106-681444, Genome Release 64-1-1, reverse complement, Verified ORF, "GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; interacts with Kap121p, Kap123p and Pdr6p (karyophilin betas); Gsp1p homolog that is not required for viability"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
691P08647    219   RAS_SCHPO Ras-like protein 1 OS=Schizosacchar...1120.00000000003     63.9     29     56GO:0071521; C:Cdc42 GTPase complex; TAS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:PomBase.
GO:0030437; P:ascospore formation; TAS:PomBase.::GO:0032488; P:Cdc42 protein signal transduction; IC:PomBase.::GO:0000751; P:cell cycle arrest in response to pheromone; TAS:PomBase.::GO:0033205; P:cell cycle cytokinesis; IGI:PomBase.::GO:0006995; P:cellular response to nitrogen starvation; IGI:PomBase.::GO:0007163; P:establishment or maintenance of cell polarity; TAS:PomBase.::GO:0009272; P:fungal-type cell wall biogenesis; IMP:PomBase.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IGI:PomBase.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0032005; P:signal transduction involved in conjugation with cellular fusion; TAS:PomBase.::GO:0007051; P:spindle organization; IGI:PomBase.
692Q9GPQ8    196   RACL_DICDI Rho-related protein racL OS=Dictyo...1370.00000000004     63.2     28     50GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
693Q4R4R6    191   CDC42_MACFA Cell division control protein 42 ...1200.00000000004     63.2     28     50GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
694Q54HZ7    189   RACM_DICDI Rho-related protein racM OS=Dictyo...1670.00000000004     62.8     26     50GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
695Q55EF0    218   RABT2_DICDI Ras-related protein RabT2 OS=Dict...1840.00000000004     63.2     26     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
696O14807    208   RASM_HUMAN Ras-related protein M-Ras OS=Homo ...1790.00000000005     62.8     33     51GO:0005886; C:plasma membrane; TAS:ProtInc.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0030742; F:GTP-dependent protein binding; IPI:UniProtKB.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
697P01120    322   RAS2_YEAST Ras-like protein 2 OS=Saccharomyce...1100.00000000005     64.3     30     60GO:0005886; C:plasma membrane; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0005525; F:GTP binding; IDA:SGD.::GO:0003924; F:GTPase activity; TAS:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007190; P:activation of adenylate cyclase activity; TAS:SGD.::GO:0030437; P:ascospore formation; IMP:SGD.::GO:0000411; P:positive regulation of transcription by galactose; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0007265; P:Ras protein signal transduction; TAS:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.
698Q7Z6P3    723   RAB44_HUMAN Ras-related protein Rab-44 OS=Hom...1610.00000000005     65.1     27     48GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
699Q86JC8    198   RABH_DICDI Ras-related protein RabH OS=Dictyo...1680.00000000005     62.8     22     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
700P18262    178   RAS_ARTSA Ras-like protein OS=Artemia salina ...1530.00000000005     62.4     25     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
701Q05062    191   CDC42_CAEEL Cell division control protein 42 ...1200.00000000005     62.4     28     51GO:0005938; C:cell cortex; IDA:WormBase.::GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0005813; C:centrosome; IDA:WormBase.::GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0016021; C:integral to membrane; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:WormBase.::GO:0005886; C:plasma membrane; IDA:WormBase.::GO:0055037; C:recycling endosome; IDA:WormBase.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0032970; P:regulation of actin filament-based process; IMP:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
702O08989    208   RASM_MOUSE Ras-related protein M-Ras OS=Mus m...1790.00000000006     62.4     34     51GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
703P20171    189   RASH_RAT GTPase HRas OS=Rattus norvegicus (Ra...1110.00000000007     62     28     54GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:RGD.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:RGD.::GO:0007265; P:Ras protein signal transduction; IMP:RGD.::GO:0035176; P:social behavior; IEP:RGD.
704Q61411    189   RASH_MOUSE GTPase HRas OS=Mus musculus (Mouse...1110.00000000007     62     28     54GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IDA:MGI.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0008283; P:cell proliferation; IPI:MGI.::GO:0006897; P:endocytosis; IDA:MGI.::GO:0008629; P:induction of apoptosis by intracellular signals; IMP:MGI.::GO:0043524; P:negative regulation of neuron apoptotic process; IDA:MGI.::GO:0010628; P:positive regulation of gene expression; IDA:MGI.::GO:0007265; P:Ras protein signal transduction; TAS:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI.
705P01112    189   RASH_HUMAN GTPase HRas OS=Homo sapiens (Human...1110.00000000007     62     28     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.::GO:0090398; P:cellular senescence; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0000165; P:MAPK cascade; TAS:Reactome.::GO:0031575; P:mitotic cell cycle G1/S transition checkpoint; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.::GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.
706P32252    197   RASB_DICDI Ras-like protein rasB OS=Dictyoste...1120.00000000007     62.4     29     55GO:0016363; C:nuclear matrix; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:dictyBase.::GO:0003924; F:GTPase activity; ISS:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase.
GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0045806; P:negative regulation of endocytosis; IMP:dictyBase.::GO:0007265; P:Ras protein signal transduction; ISS:dictyBase.::GO:0051726; P:regulation of cell cycle; IEP:dictyBase.::GO:0042127; P:regulation of cell proliferation; IMP:dictyBase.::GO:0051270; P:regulation of cellular component movement; IGI:dictyBase.
707Q9P8J9    206   RHO3_SCHCO GTP-binding protein Rho3 OS=Schizo...1670.00000000007     62.4     28     47GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
708P05774    183   RAS_CARAU Ras-like protein OS=Carassius aurat...1110.00000000008     62     29     53GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
709P97538    208   RASM_RAT Ras-related protein M-Ras OS=Rattus ...1790.00000000009     62     34     51GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
710P87027    198   SPG1_SCHPO Septum-promoting GTP-binding prote...1280.0000000001     62     27     48GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005525; F:GTP binding; IC:PomBase.::GO:0003924; F:GTPase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031028; P:septation initiation signaling cascade; IGI:PomBase.
711Q54FG4    232   RABP_DICDI Ras-related protein RabP OS=Dictyo...1380.0000000001     62.4     29     51GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
712P28775    217   RAS_LENED Ras-like protein OS=Lentinula edode...1120.0000000001     62     29     58GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
713O42785    214   RASL_COLTR Ras-like protein OS=Colletotrichum...1120.0000000001     61.6     29     59GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
714P08644    189   RASK_RAT GTPase KRas OS=Rattus norvegicus (Ra...1110.0000000001     61.2     29     53GO:0045121; C:membrane raft; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0019003; F:GDP binding; IDA:RGD.::GO:0019002; F:GMP binding; IDA:RGD.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0030275; F:LRR domain binding; IDA:RGD.
GO:0019221; P:cytokine-mediated signaling pathway; IMP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:RGD.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:RGD.::GO:0051000; P:positive regulation of nitric-oxide synthase activity; IMP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0051385; P:response to mineralocorticoid stimulus; IEP:RGD.::GO:0035176; P:social behavior; IEP:RGD.
715P32883    189   RASK_MOUSE GTPase KRas OS=Mus musculus (Mouse...1110.0000000001     61.2     29     53GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IGI:MGI.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.::GO:0035022; P:positive regulation of Rac protein signal transduction; IGI:MGI.::GO:0007265; P:Ras protein signal transduction; IGI:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IGI:MGI.::GO:0032228; P:regulation of synaptic transmission, GABAergic; IGI:MGI.::GO:0051146; P:striated muscle cell differentiation; IGI:MGI.::GO:0008542; P:visual learning; IGI:MGI.
716P01116    189   RASK_HUMAN GTPase KRas OS=Homo sapiens (Human...1110.0000000001     61.2     29     53GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0000165; P:MAPK cascade; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
717P08642    189   RASH_CHICK GTPase HRas OS=Gallus gallus (Chic...1110.0000000002     61.2     28     53GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
718Q8BU31    183   RAP2C_MOUSE Ras-related protein Rap-2c OS=Mus...1550.0000000002     60.8     28     52GO:0005829; C:cytosol; IDA:MGI.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0031954; P:positive regulation of protein autophosphorylation; IDA:MGI.::GO:0032486; P:Rap protein signal transduction; IDA:UniProtKB.::GO:0061097; P:regulation of protein tyrosine kinase activity; IDA:UniProtKB.
719Q9Y3L5    183   RAP2C_HUMAN Ras-related protein Rap-2c OS=Hom...1550.0000000002     60.8     28     52GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0031954; P:positive regulation of protein autophosphorylation; ISS:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0061097; P:regulation of protein tyrosine kinase activity; ISS:UniProtKB.
720Q08DI5    183   RAP2C_BOVIN Ras-related protein Rap-2c OS=Bos...1550.0000000002     60.8     28     52GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0031954; P:positive regulation of protein autophosphorylation; ISS:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0061097; P:regulation of protein tyrosine kinase activity; ISS:UniProtKB.
721P04388    192   RAS2_DROME Ras-like protein 2 OS=Drosophila m...1110.0000000002     60.8     29     55GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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