UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOR157C

Length:

261

Number of sequences:

5887

Description:

YOR157C PUP1 SGDID:S000005683, Chr XV from 631751-630966, Genome Release 64-1-1, reverse complement, Verified ORF, "Beta 2 subunit of the 20S proteasome; endopeptidase with trypsin-like activity that cleaves after basic residues; synthesized as a proprotein before being proteolytically processed for assembly into 20S particle; human homolog is subunit Z"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P25043	261	PSB7_YEAST Proteasome component PUP1 OS=Sacch...	261	0	544	100	100	GO:0005789; C:endoplasmic reticulum membrane; IC:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0019774; C:proteasome core complex, beta-subunit complex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:SGD.
2	Q09841	267	PSB7_SCHPO Probable proteasome subunit beta t...	260	6e-109	322	62	75	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.::GO:0019774; C:proteasome core complex, beta-subunit complex; ISS:PomBase.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
3	Q9JHW0	277	PSB7_RAT Proteasome subunit beta type-7 OS=Ra...	262	4e-96	290	55	73	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
4	P70195	277	PSB7_MOUSE Proteasome subunit beta type-7 OS=...	262	5e-96	290	55	73	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
5	Q99436	277	PSB7_HUMAN Proteasome subunit beta type-7 OS=...	262	9e-96	289	55	72	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
6	Q2TBP0	277	PSB7_BOVIN Proteasome subunit beta type-7 OS=...	262	3e-95	288	55	72	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
7	A1XQU1	277	PSB7_PIG Proteasome subunit beta type-7 OS=Su...	262	1e-94	286	54	73	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
8	Q7DLS1	274	PSB7B_ARATH Proteasome subunit beta type-7-B ...	242	1e-90	276	54	72	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
9	O23710	273	PSB7A_ARATH Proteasome subunit beta type-7-A ...	242	2e-90	275	53	72	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
10	Q54QR2	266	PSB7_DICDI Proteasome subunit beta type-7 OS=...	244	9e-84	258	57	70	GO:0005737; C:cytoplasm; IPI:dictyBase.::GO:0005634; C:nucleus; IPI:dictyBase.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
11	Q3T0T1	273	PSB10_BOVIN Proteasome subunit beta type-10 O...	258	7e-75	235	48	65	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
12	P40306	273	PSB10_HUMAN Proteasome subunit beta type-10 O...	258	5e-74	233	47	64	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0006959; P:humoral immune response; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
13	O35955	273	PSB10_MOUSE Proteasome subunit beta type-10 O...	258	4e-73	231	47	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0000902; P:cell morphogenesis; IMP:MGI.::GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.::GO:0042098; P:T cell proliferation; IMP:MGI.
14	Q4KM35	273	PSB10_RAT Proteasome subunit beta type-10 OS=...	258	7e-71	225	46	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
15	Q8SQN7	227	PSB7_ENCCU Probable proteasome subunit beta t...	224	6e-67	213	49	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
16	B1L6S7	206	PSB1_KORCO Proteasome subunit beta 1 OS=Korar...	200	8e-29	114	35	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
17	A1RX71	204	PSB2_THEPD Proteasome subunit beta 2 OS=Therm...	196	4e-28	112	34	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
18	A2SS78	212	PSB_METLZ Proteasome subunit beta OS=Methanoc...	204	6e-27	108	35	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
19	B8GG66	211	PSB_METPE Proteasome subunit beta OS=Methanos...	190	9e-26	105	33	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
20	Q74MP5	196	PSB_NANEQ Proteasome subunit beta OS=Nanoarch...	180	1e-25	104	32	59	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
21	B9LTS6	243	PSB_HALLT Proteasome subunit beta OS=ACAM 34)...	186	2e-25	105	38	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
22	Q2NI68	205	PSB_METST Proteasome subunit beta OS=Methanos...	179	2e-25	104	35	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
23	Q3MHN0	239	PSB6_BOVIN Proteasome subunit beta type-6 OS=...	221	5e-25	104	30	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
24	P28072	239	PSB6_HUMAN Proteasome subunit beta type-6 OS=...	179	6e-25	103	32	58	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005839; C:proteasome core complex; NAS:UniProtKB.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
25	Q60692	238	PSB6_MOUSE Proteasome subunit beta type-6 OS=...	186	7e-25	103	31	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
26	D1Z199	205	PSB_METPS Proteasome subunit beta OS=SANAE). ...	185	9e-25	102	33	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
27	Q18GX3	243	PSB_HALWD Proteasome subunit beta OS=Haloquad...	184	2e-24	102	34	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
28	D4GYZ1	243	PSB_HALVD Proteasome subunit beta OS=14742 / ...	199	4e-24	102	36	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019774; C:proteasome core complex, beta-subunit complex; IDA:UniProtKB.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0010498; P:proteasomal protein catabolic process; IDA:UniProtKB.
29	P28073	238	PSB6_RAT Proteasome subunit beta type-6 OS=Ra...	186	4e-24	101	30	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
30	A9A2U7	210	PSB2_NITMS Proteasome subunit beta 2 OS=Nitro...	182	5e-24	100	33	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
31	O43063	226	PSB6_SCHPO Probable proteasome subunit beta t...	180	7e-24	100	29	57	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0019774; C:proteasome core complex, beta-subunit complex; ISS:PomBase.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; NAS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.

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