rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q12216 | 726 | SIZ2_YEAST E3 SUMO-protein ligase SIZ2 OS=Sac... | 726 | 0 | 1508 | 100 | 100 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000790; C:nuclear chromatin; IDA:SGD. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0019789; F:SUMO ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030261; P:chromosome condensation; TAS:SGD.::GO:0007059; P:chromosome segregation; IMP:SGD.::GO:0016925; P:protein sumoylation; IDA:SGD. | 2 | Q04195 | 904 | SIZ1_YEAST E3 SUMO-protein ligase SIZ1 OS=Sac... | 492 | 8e-113 | 369 | 41 | 58 | GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0000790; C:nuclear chromatin; IDA:SGD.::GO:0005940; C:septin ring; IDA:SGD. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0019789; F:SUMO ligase activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007059; P:chromosome segregation; IMP:SGD.::GO:0016925; P:protein sumoylation; IMP:SGD. | 3 | O94451 | 727 | PLI1_SCHPO E3 SUMO-protein ligase pli1 OS=Sch... | 400 | 1e-39 | 159 | 31 | 49 | GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0019789; F:SUMO ligase activity; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030999; P:linear element assembly; IMP:PomBase.::GO:0016925; P:protein sumoylation; IMP:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.::GO:0051983; P:regulation of chromosome segregation; IMP:PomBase.::GO:0000019; P:regulation of mitotic recombination; IMP:PomBase.::GO:0032204; P:regulation of telomere maintenance; IMP:PomBase. | 4 | Q8N2W9 | 510 | PIAS4_HUMAN E3 SUMO-protein ligase PIAS4 OS=H... | 173 | 6e-28 | 122 | 34 | 54 | GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019789; F:SUMO ligase activity; IDA:BHF-UCL.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 5 | Q9JM05 | 507 | PIAS4_MOUSE E3 SUMO-protein ligase PIAS4 OS=M... | 173 | 7e-27 | 118 | 32 | 54 | GO:0016363; C:nuclear matrix; IDA:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:MGI.::GO:0019789; F:SUMO ligase activity; IDA:MGI.::GO:0003714; F:transcription corepressor activity; IDA:MGI.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; NAS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IDA:BHF-UCL.::GO:0033235; P:positive regulation of protein sumoylation; ISS:UniProtKB.::GO:0016925; P:protein sumoylation; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 6 | Q6AZ28 | 572 | PIAS2_RAT E3 SUMO-protein ligase PIAS2 OS=Rat... | 287 | 3e-22 | 105 | 26 | 45 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IPI:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035259; F:glucocorticoid receptor binding; IPI:RGD.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:RGD.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:MGI.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.::GO:0007283; P:spermatogenesis; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | O75928 | 621 | PIAS2_HUMAN E3 SUMO-protein ligase PIAS2 OS=H... | 287 | 4e-22 | 105 | 26 | 45 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019789; F:SUMO ligase activity; IDA:BHF-UCL.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q8C5D8 | 621 | PIAS2_MOUSE E3 SUMO-protein ligase PIAS2 OS=M... | 287 | 6e-22 | 104 | 26 | 45 | GO:0016604; C:nuclear body; IDA:MGI.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0019789; F:SUMO ligase activity; IDA:MGI.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0016925; P:protein sumoylation; IDA:MGI.::GO:0045667; P:regulation of osteoblast differentiation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | O88907 | 651 | PIAS1_MOUSE E3 SUMO-protein ligase PIAS1 OS=M... | 213 | 1e-20 | 100 | 29 | 49 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0033235; P:positive regulation of protein sumoylation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | O75925 | 651 | PIAS1_HUMAN E3 SUMO-protein ligase PIAS1 OS=H... | 179 | 1e-19 | 97.4 | 30 | 51 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0019789; F:SUMO ligase activity; IDA:BHF-UCL.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.::GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | Q9Y6X2 | 628 | PIAS3_HUMAN E3 SUMO-protein ligase PIAS3 OS=H... | 172 | 8e-19 | 94.7 | 31 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | O70260 | 628 | PIAS3_RAT E3 SUMO-protein ligase PIAS3 OS=Rat... | 172 | 9e-19 | 94.4 | 31 | 52 | GO:0030425; C:dendrite; IDA:RGD.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IDA:RGD. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0015459; F:potassium channel regulator activity; IDA:RGD.::GO:0008022; F:protein C-terminus binding; IDA:RGD.::GO:0047485; F:protein N-terminus binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010628; P:positive regulation of gene expression; IDA:RGD.::GO:0045838; P:positive regulation of membrane potential; IDA:RGD.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009725; P:response to hormone stimulus; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | O54714 | 628 | PIAS3_MOUSE E3 SUMO-protein ligase PIAS3 OS=M... | 172 | 9e-19 | 94.4 | 31 | 52 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0019789; F:SUMO ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0033235; P:positive regulation of protein sumoylation; ISS:UniProtKB.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | Q8NF64 | 920 | ZMIZ2_HUMAN Zinc finger MIZ domain-containing... | 117 | 0.000000000000003 | 83.6 | 32 | 55 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0043596; C:nuclear replication fork; IDA:UniProtKB. | | | | | | | | | | GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | Q8CIE2 | 920 | ZMIZ2_MOUSE Zinc finger MIZ domain-containing... | 117 | 0.000000000000003 | 83.6 | 32 | 55 | GO:0043596; C:nuclear replication fork; ISS:UniProtKB. | | | | | | | | | | GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB. | 16 | Q94361 | 793 | GEI17_CAEEL E3 SUMO-protein ligase gei-17 OS=... | 218 | 0.000000000000004 | 83.2 | 24 | 47 | | | | | | | | | | | GO:0001085; F:RNA polymerase II transcription factor binding; IPI:WormBase.::GO:0019789; F:SUMO ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0016925; P:protein sumoylation; IDA:WormBase. | 17 | Q6L4L4 | 875 | SIZ1_ORYSJ E3 SUMO-protein ligase SIZ1 OS=Ory... | 118 | 0.00000000000006 | 79.3 | 32 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 18 | Q9ULJ6 | 1067 | ZMIZ1_HUMAN Zinc finger MIZ domain-containing... | 147 | 0.0000000000003 | 77.4 | 29 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q6P1E1 | 1072 | ZMIZ1_MOUSE Zinc finger MIZ domain-containing... | 147 | 0.0000000000003 | 77 | 29 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q6ASW7 | 813 | SIZ2_ORYSJ E3 SUMO-protein ligase SIZ2 OS=Ory... | 98 | 0.000000000003 | 73.6 | 31 | 56 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 21 | Q680Q4 | 884 | SIZ1_ARATH E3 SUMO-protein ligase SIZ1 OS=Ara... | 155 | 0.0000000002 | 68.2 | 26 | 46 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0019789; F:SUMO ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IMP:TAIR.::GO:0016049; P:cell growth; IMP:TAIR.::GO:0016036; P:cellular response to phosphate starvation; IMP:TAIR.::GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0010247; P:detection of phosphate ion; IDA:TAIR.::GO:0048589; P:developmental growth; IMP:UniProtKB.::GO:0009908; P:flower development; IEA:UniProtKB-KW.::GO:0010286; P:heat acclimation; IMP:UniProtKB.::GO:0009910; P:negative regulation of flower development; IMP:TAIR.::GO:0010113; P:negative regulation of systemic acquired resistance; IMP:UniProtKB.::GO:0016925; P:protein sumoylation; IDA:UniProtKB.::GO:0009787; P:regulation of abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0040008; P:regulation of growth; IMP:TAIR.::GO:0090352; P:regulation of nitrate assimilation; IMP:TAIR.::GO:2000070; P:regulation of response to water deprivation; IMP:TAIR.::GO:0010337; P:regulation of salicylic acid metabolic process; IMP:TAIR.::GO:0050826; P:response to freezing; IMP:TAIR.::GO:0009414; P:response to water deprivation; IMP:UniProtKB. | 22 | Q8K243 | 485 | TRI68_MOUSE E3 ubiquitin-protein ligase TRIM6... | 82 | 0.038 | 40.8 | 28 | 49 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035035; F:histone acetyltransferase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 23 | O54952 | 1817 | BRCA1_RAT Breast cancer type 1 susceptibility... | 69 | 0.084 | 40 | 33 | 55 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IDA:RGD. | | | | | | | | | | GO:0003684; F:damaged DNA binding; TAS:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD. | 24 | Q6AZZ1 | 485 | TRI68_HUMAN E3 ubiquitin-protein ligase TRIM6... | 81 | 0.14 | 38.9 | 26 | 48 | GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IPI:UniProtKB.::GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:UniProtKB. | 25 | Q864U1 | 1849 | BRCA1_BOVIN Breast cancer type 1 susceptibili... | 69 | 0.24 | 38.5 | 32 | 55 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB. | 26 | Q9Y6R7 | 5405 | FCGBP_HUMAN IgGFc-binding protein OS=Homo sap... | 117 | 2.2 | 35.4 | 27 | 45 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | | 27 | Q95153 | 1878 | BRCA1_CANFA Breast cancer type 1 susceptibili... | 69 | 0.28 | 38.5 | 32 | 55 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB. | 28 | Q96MF7 | 247 | NSE2_HUMAN E3 SUMO-protein ligase NSE2 OS=Hom... | 86 | 2.1 | 34.7 | 31 | 44 | GO:0000781; C:chromosome, telomeric region; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB.::GO:0030915; C:Smc5-Smc6 complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0019789; F:SUMO ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0090398; P:cellular senescence; IMP:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0034184; P:positive regulation of maintenance of mitotic sister chromatid cohesion; IMP:UniProtKB.::GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; IMP:UniProtKB.::GO:0000722; P:telomere maintenance via recombination; IMP:UniProtKB. | 29 | Q99728 | 777 | BARD1_HUMAN BRCA1-associated RING domain prot... | 69 | 3.8 | 34.7 | 28 | 46 | GO:0070531; C:BRCA1-A complex; IDA:UniProtKB.::GO:0031436; C:BRCA1-BARD1 complex; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007050; P:cell cycle arrest; NAS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0031441; P:negative regulation of mRNA 3'-end processing; NAS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; NAS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0042325; P:regulation of phosphorylation; IMP:UniProtKB.::GO:0001894; P:tissue homeostasis; TAS:UniProtKB. | 30 | Q2H0I3 | 622 | KU70_CHAGB ATP-dependent DNA helicase II subu... | 61 | 4.5 | 34.3 | 31 | 61 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005958; C:DNA-dependent protein kinase-DNA ligase 4 complex; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro. | 31 | P38632 | 267 | NSE2_YEAST E3 SUMO-protein ligase MMS21 OS=Sa... | 59 | 7.1 | 33.1 | 32 | 46 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005635; C:nuclear envelope; IDA:SGD.::GO:0030915; C:Smc5-Smc6 complex; IDA:SGD. | | | | | | | | | | GO:0019789; F:SUMO ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IMP:SGD. |