rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P28241 | 369 | IDH2_YEAST Isocitrate dehydrogenase [NAD] sub... | 369 | 0 | 753 | 100 | 100 | GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IDA:SGD. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006537; P:glutamate biosynthetic process; TAS:SGD.::GO:0006102; P:isocitrate metabolic process; TAS:SGD.::GO:0006099; P:tricarboxylic acid cycle; TAS:SGD. | 2 | O94230 | 368 | IDH2_KLULA Isocitrate dehydrogenase [NAD] sub... | 369 | 0 | 644 | 84 | 92 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 3 | Q9USP8 | 378 | IDH2_SCHPO Isocitrate dehydrogenase [NAD] sub... | 365 | 7e-161 | 463 | 62 | 77 | GO:0005759; C:mitochondrial matrix; ISS:PomBase. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IMP:PomBase.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006537; P:glutamate biosynthetic process; IMP:PomBase.::GO:0006102; P:isocitrate metabolic process; IMP:PomBase.::GO:0006099; P:tricarboxylic acid cycle; IMP:PomBase. | 4 | Q9VWH4 | 377 | IDH3A_DROME Probable isocitrate dehydrogenase... | 338 | 1e-131 | 388 | 57 | 73 | GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; ISS:UniProtKB. | 5 | Q93714 | 358 | IDH3A_CAEEL Probable isocitrate dehydrogenase... | 332 | 9e-130 | 383 | 59 | 72 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 6 | Q945K7 | 374 | IDH5_ARATH Isocitrate dehydrogenase [NAD] cat... | 342 | 2e-121 | 362 | 54 | 72 | GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:TAIR.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IMP:TAIR.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:TAIR. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; IMP:TAIR.::GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 7 | Q9D6R2 | 366 | IDH3A_MOUSE Isocitrate dehydrogenase [NAD] su... | 337 | 3e-120 | 359 | 56 | 71 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 8 | P50213 | 366 | IDH3A_HUMAN Isocitrate dehydrogenase [NAD] su... | 337 | 1e-119 | 357 | 55 | 70 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome. | 9 | Q55BI2 | 354 | IDHA_DICDI Isocitrate dehydrogenase [NAD] reg... | 332 | 2e-119 | 357 | 55 | 73 | GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 10 | Q5R678 | 366 | IDH3A_PONAB Isocitrate dehydrogenase [NAD] su... | 337 | 2e-119 | 357 | 55 | 70 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 11 | Q28480 | 347 | IDH3A_MACFA Isocitrate dehydrogenase [NAD] su... | 337 | 3e-119 | 356 | 55 | 70 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 12 | P41563 | 366 | IDH3A_BOVIN Isocitrate dehydrogenase [NAD] su... | 337 | 4e-119 | 356 | 55 | 70 | GO:0005739; C:mitochondrion; ISS:AgBase. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 13 | Q99NA5 | 366 | IDH3A_RAT Isocitrate dehydrogenase [NAD] subu... | 337 | 4e-118 | 353 | 55 | 70 | GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IC:RGD. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IDA:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006102; P:isocitrate metabolic process; IDA:RGD.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD. | 14 | Q8LG77 | 374 | IDH6_ARATH Isocitrate dehydrogenase [NAD] cat... | 335 | 2e-117 | 352 | 55 | 72 | GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 15 | P29696 | 357 | LEU3_SOLTU 3-isopropylmalate dehydrogenase, c... | 310 | 6e-112 | 337 | 56 | 73 | GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro. | 16 | Q54B68 | 360 | IDHB_DICDI Isocitrate dehydrogenase [NAD] reg... | 334 | 3e-105 | 320 | 51 | 67 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 17 | O94229 | 361 | IDH1_KLULA Isocitrate dehydrogenase [NAD] sub... | 345 | 7e-95 | 294 | 46 | 64 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 18 | O13302 | 388 | IDH1_AJECA Isocitrate dehydrogenase [NAD] sub... | 370 | 1e-94 | 294 | 42 | 62 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 19 | P28834 | 360 | IDH1_YEAST Isocitrate dehydrogenase [NAD] sub... | 366 | 5e-90 | 281 | 42 | 63 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005758; C:mitochondrial intermembrane space; TAS:Reactome.::GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IDA:SGD.::GO:0042645; C:mitochondrial nucleoid; IDA:SGD. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006537; P:glutamate biosynthetic process; TAS:SGD.::GO:0006102; P:isocitrate metabolic process; TAS:SGD.::GO:0006099; P:tricarboxylic acid cycle; TAS:SGD. | 20 | Q8LFC0 | 367 | IDH1_ARATH Isocitrate dehydrogenase [NAD] reg... | 347 | 7e-89 | 278 | 43 | 64 | GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:TAIR. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; IMP:TAIR.::GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 21 | O81796 | 368 | IDH3_ARATH Isocitrate dehydrogenase [NAD] reg... | 367 | 2e-87 | 275 | 42 | 61 | GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IGI:TAIR.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; IGI:TAIR.::GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 22 | P33197 | 496 | IDH_THET8 Isocitrate dehydrogenase [NADP] OS=... | 342 | 2e-87 | 279 | 44 | 64 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 23 | O13696 | 356 | IDH1_SCHPO Isocitrate dehydrogenase [NAD] sub... | 345 | 4e-87 | 274 | 44 | 63 | GO:0005759; C:mitochondrial matrix; ISS:PomBase. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IMP:PomBase.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006537; P:glutamate biosynthetic process; IMP:PomBase.::GO:0006102; P:isocitrate metabolic process; IMP:PomBase.::GO:0006099; P:tricarboxylic acid cycle; IMP:PomBase. | 24 | P93032 | 367 | IDH2_ARATH Isocitrate dehydrogenase [NAD] reg... | 377 | 5e-87 | 274 | 40 | 62 | GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 25 | Q1RJU4 | 483 | IDH_RICBR Isocitrate dehydrogenase [NADP] OS=... | 335 | 5e-78 | 254 | 44 | 61 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 26 | P41564 | 355 | IDH3G_MACFA Isocitrate dehydrogenase [NAD] su... | 339 | 6e-78 | 250 | 41 | 63 | GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 27 | P51553 | 393 | IDH3G_HUMAN Isocitrate dehydrogenase [NAD] su... | 339 | 2e-77 | 249 | 41 | 63 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome. | 28 | P70404 | 393 | IDHG1_MOUSE Isocitrate dehydrogenase [NAD] su... | 339 | 4e-77 | 249 | 40 | 63 | GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 29 | P41565 | 393 | IDHG1_RAT Isocitrate dehydrogenase [NAD] subu... | 339 | 4e-77 | 249 | 40 | 63 | GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IC:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0045926; P:negative regulation of growth; IMP:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD. | 30 | Q58CP0 | 392 | IDH3G_BOVIN Isocitrate dehydrogenase [NAD] su... | 343 | 1e-76 | 248 | 40 | 62 | GO:0005739; C:mitochondrion; ISS:AgBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 31 | O77784 | 385 | IDH3B_BOVIN Isocitrate dehydrogenase [NAD] su... | 358 | 5e-76 | 246 | 39 | 62 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. |