Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR127W
Length:
1007
Number of sequences:
5887
Description:
YOR127W RGA1 SGDID:S000005653, Chr XV from 561170-564193, Genome Release 64-1-1, Verified ORF, "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
391P29675    219   SF3_HELAN Pollen-specific protein SF3 OS=Heli...684.4     34.3     29     43
GO:0008270; F:zinc ion binding; IEA:InterPro.
392Q9Z0S2    406   LHX2_MOUSE LIM/homeobox protein Lhx2 OS=Mus m...1284.5     34.7     23     39GO:0005634; C:nucleus; IDA:MGI.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000988; F:protein binding transcription factor activity; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:MGI.::GO:0009953; P:dorsal/ventral pattern formation; IMP:MGI.::GO:0007498; P:mesoderm development; IMP:MGI.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IGI:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0021978; P:telencephalon regionalization; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
393Q15654    476   TRIP6_HUMAN Thyroid receptor-interacting prot...1094.8     34.7     27     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005149; F:interleukin-1 receptor binding; IDA:UniProtKB.::GO:0019900; F:kinase binding; IPI:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048041; P:focal adhesion assembly; NAS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008588; P:release of cytoplasmic sequestered NF-kappaB; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
394Q6INE5    507   RHG19_XENLA Rho GTPase-activating protein 19 ...1704.9     34.7     25     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
395Q62523    564   ZYX_MOUSE Zyxin OS=Mus musculus (Mouse). GN=Z...974.9     34.7     29     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
396Q54BP9    520   GACV_DICDI Rho GTPase-activating protein gacV...845     34.7     24     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
397O54874    1732   MRCKA_RAT Serine/threonine-protein kinase MRC...795     35     33     49GO:0042641; C:actomyosin; IDA:UniProtKB.::GO:0031252; C:cell leading edge; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IDA:UniProtKB.
398Q60564    369   LMX1B_MESAU LIM homeobox transcription factor...1155.3     34.3     23     34GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
399P53413    377   LMX1B_CHICK LIM/homeobox protein LMX-1.2 OS=G...1155.5     34.3     23     34GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
400Q1JQB5    378   FBLI1_BOVIN Filamin-binding LIM protein 1 OS=...946.1     34.3     26     47GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; ISS:UniProtKB.
GO:0031005; F:filamin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0033623; P:regulation of integrin activation; ISS:UniProtKB.
401Q55CK2    877   MGP2_DICDI Mental retardation GTPase activati...1926.1     34.7     22     44GO:0000331; C:contractile vacuole; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0033298; P:contractile vacuole organization; IGI:dictyBase.::GO:0006887; P:exocytosis; IGI:dictyBase.::GO:0051490; P:negative regulation of filopodium assembly; IMP:dictyBase.::GO:0042331; P:phototaxis; IGI:dictyBase.::GO:0051270; P:regulation of cellular component movement; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase.
402P50462    194   CSRP3_MOUSE Cysteine and glycine-rich protein...626.2     33.5     24     44GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:MGI.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048738; P:cardiac muscle tissue development; IGI:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006874; P:cellular calcium ion homeostasis; IGI:MGI.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0002026; P:regulation of the force of heart contraction; IGI:MGI.
403Q4U0T9    194   CSRP3_BOVIN Cysteine and glycine-rich protein...626.2     33.5     24     44GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
404P17121    654   SAC7_YEAST GTPase-activating protein SAC7 OS=...1016.5     34.3     21     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005100; F:Rho GTPase activator activity; TAS:SGD.
GO:0030037; P:actin filament reorganization involved in cell cycle; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD.
405P50461    194   CSRP3_HUMAN Cysteine and glycine-rich protein...626.6     33.5     24     44GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007519; P:skeletal muscle tissue development; TAS:ProtInc.
406Q6H8Q1    611   ABLM2_HUMAN Actin-binding LIM protein 2 OS=Ho...1086.6     34.3     27     36GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.
407Q68EY3    331   LHX9_XENLA LIM/homeobox protein Lhx9 OS=Xenop...1177.1     33.9     23     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
408P47226    423   TES_MOUSE Testin OS=Mus musculus (Mouse). GN=...1167.7     33.9     22     41GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
409Q9N0A8    526   ARHG3_MACFA Rho guanine nucleotide exchange f...1768.2     33.9     25     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
410Q9NR81    526   ARHG3_HUMAN Rho guanine nucleotide exchange f...1768.3     33.9     25     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; TAS:ProtInc.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
411Q9FKN7    1613   DAR4_ARATH Protein DA1-related 4 OS=Arabidops...688.4     34.3     31     50
GO:0043531; F:ADP binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:InterPro.
412B0SUP8    1394   RPOC_CAUSK DNA-directed RNA polymerase subuni...1808.6     34.3     26     41
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
413Q9JKU8    382   LMX1A_MOUSE LIM homeobox transcription factor...1628.6     33.9     24     35GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:MGI.::GO:0021953; P:central nervous system neuron differentiation; IMP:MGI.::GO:0021549; P:cerebellum development; IMP:MGI.::GO:0021542; P:dentate gyrus development; IMP:MGI.::GO:0071542; P:dopaminergic neuron differentiation; IMP:MGI.::GO:0030901; P:midbrain development; IMP:MGI.::GO:0045665; P:negative regulation of neuron differentiation; IMP:MGI.::GO:0001558; P:regulation of cell growth; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
414Q5R6F2    526   ARHG3_PONAB Rho guanine nucleotide exchange f...1768.6     33.9     25     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
415Q8MML5    569   PAXB_DICDI Paxillin-B OS=Dictyostelium discoi...1789     33.9     22     30GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0032433; C:filopodium tip; IDA:dictyBase.::GO:0005925; C:focal adhesion; IDA:dictyBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016339; P:calcium-dependent cell-cell adhesion; IMP:dictyBase.::GO:0016477; P:cell migration; IMP:dictyBase.::GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.::GO:0007109; P:cytokinesis, completion of separation; IMP:dictyBase.
416Q91X46    524   ARHG3_MOUSE Rho guanine nucleotide exchange f...1769.1     33.9     25     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
417A7MB27    530   RHG36_BOVIN Rho GTPase-activating protein 36 ...2119.5     33.9     22     41GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
418P37137    402   LHX5_XENLA LIM/homeobox protein Lhx5 OS=Xenop...1089.7     33.5     22     35GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
419Q54QR1    1183   LIMA_DICDI LIM domain-containing protein A OS...1409.9     33.9     25     35
GO:0008270; F:zinc ion binding; IEA:InterPro.
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