Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR127W
Length:
1007
Number of sequences:
5887
Description:
YOR127W RGA1 SGDID:S000005653, Chr XV from 561170-564193, Genome Release 64-1-1, Verified ORF, "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211P53667    647   LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapie...2550.0002     48.9     24     37GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0043005; C:neuron projection; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IDA:BHF-UCL.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051444; P:negative regulation of ubiquitin-protein ligase activity; IDA:BHF-UCL.::GO:0032233; P:positive regulation of actin filament bundle assembly; IDA:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; ISS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
212Q99MB5    145   LMO3_RAT LIM domain only protein 3 OS=Rattus ...1410.0002     45.8     23     37
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
213Q3SX40    424   PDLI7_BOVIN PDZ and LIM domain protein 7 OS=B...1290.056     40.8     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.
214Q9U1I1    785   ESN_DROME Protein espinas OS=Drosophila melan...1200.0003     48.5     28     43
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070593; P:dendrite self-avoidance; IMP:FlyBase.
215Q3TJD7    457   PDLI7_MOUSE PDZ and LIM domain protein 7 OS=M...1290.044     41.2     26     40GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI.::GO:0001725; C:stress fiber; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IPI:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.
216P53668    647   LIMK1_MOUSE LIM domain kinase 1 OS=Mus muscul...2550.0004     48.1     24     37GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0043005; C:neuron projection; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045773; P:positive regulation of axon extension; IGI:MGI.
217P53669    647   LIMK1_RAT LIM domain kinase 1 OS=Rattus norve...2550.0006     47.4     23     37GO:0044295; C:axonal growth cone; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045773; P:positive regulation of axon extension; ISS:UniProtKB.
218Q28FG2    833   PRIC1_XENTR Prickle-like protein 1 OS=Xenopus...650.52     38.1     34     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB.
219Q90Z06    835   PRI1A_XENLA Prickle-like protein 1-A OS=Xenop...660.54     37.7     33     50GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; IMP:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; IMP:UniProtKB.::GO:0001736; P:establishment of planar polarity; IMP:UniProtKB.
220P61969    165   LMO4_MOUSE LIM domain transcription factor LM...1450.0008     44.7     23     37GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0001158; F:enhancer sequence-specific DNA binding; IDA:MGI.::GO:0008134; F:transcription factor binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031333; P:negative regulation of protein complex assembly; IDA:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0050865; P:regulation of cell activation; IMP:MGI.::GO:0042659; P:regulation of cell fate specification; IMP:MGI.::GO:0021527; P:spinal cord association neuron differentiation; IGI:MGI.::GO:0021522; P:spinal cord motor neuron differentiation; IDA:MGI.::GO:0048538; P:thymus development; IGI:MGI.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:MGI.::GO:0021514; P:ventral spinal cord interneuron differentiation; IDA:MGI.::GO:0003281; P:ventricular septum development; IMP:MGI.
221P61968    165   LMO4_HUMAN LIM domain transcription factor LM...1450.0008     44.7     23     37GO:0005667; C:transcription factor complex; ISS:UniProtKB.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001843; P:neural tube closure; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
222Q3SWZ8    165   LMO4_BOVIN LIM domain transcription factor LM...1450.0008     44.7     23     37
GO:0008270; F:zinc ion binding; IEA:InterPro.
223Q54GD0    920   MGP1_DICDI Mental retardation GTPase activati...2100.001     47     23     44GO:0000331; C:contractile vacuole; IDA:dictyBase.::GO:0005829; C:cytosol; IDA:dictyBase.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0033298; P:contractile vacuole organization; IMP:dictyBase.::GO:0006887; P:exocytosis; IGI:dictyBase.::GO:0051490; P:negative regulation of filopodium assembly; IMP:dictyBase.::GO:0042331; P:phototaxis; IGI:dictyBase.::GO:0051270; P:regulation of cellular component movement; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro.
224Q6DJ06    165   LMO42_XENTR LIM domain transcription factor L...1450.001     44.3     23     37
GO:0003712; F:transcription cofactor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
225Q90WV2    832   PRI1B_XENLA Prickle-like protein 1-B OS=Xenop...650.62     37.7     34     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; ISS:UniProtKB.
226O43182    974   RHG06_HUMAN Rho GTPase-activating protein 6 O...1760.001     46.6     23     48GO:0005884; C:actin filament; NAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0016004; F:phospholipase activator activity; IDA:BHF-UCL.::GO:0043274; F:phospholipase binding; IPI:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0030041; P:actin filament polymerization; NAS:UniProtKB.::GO:0007202; P:activation of phospholipase C activity; IDA:BHF-UCL.::GO:0051895; P:negative regulation of focal adhesion assembly; IMP:BHF-UCL.::GO:0051497; P:negative regulation of stress fiber assembly; IMP:BHF-UCL.::GO:0007266; P:Rho protein signal transduction; NAS:UniProtKB.
227Q5FVB2    167   LMO41_XENTR LIM domain transcription factor L...950.001     43.9     24     38
GO:0003712; F:transcription cofactor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
228A7E300    1112   RHG07_BOVIN Rho GTPase-activating protein 7 O...1920.001     46.2     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
229O14639    778   ABLM1_HUMAN Actin-binding LIM protein 1 OS=Ho...1197.8     34.3     24     37GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0007601; P:visual perception; TAS:ProtInc.
230Q06BR1    612   LIMD1_XENLA LIM domain-containing protein 1 O...1370.002     45.8     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0014032; P:neural crest cell development; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
231Q9Z1Z9    457   PDLI7_RAT PDZ and LIM domain protein 7 OS=Rat...1290.017     42.4     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0045669; P:positive regulation of osteoblast differentiation; IDA:RGD.
232B7ZUL2    593   LIMD1_XENTR LIM domain-containing protein 1 O...1350.002     45.8     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0014032; P:neural crest cell development; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
233A9LS46    690   WTIP_XENLA Wilms tumor protein 1-interacting ...1370.002     45.8     25     42GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0014032; P:neural crest cell development; IMP:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
234Q0P5B3    156   RBTN1_BOVIN Rhombotin-1 OS=Bos taurus (Bovine...1100.002     43.5     23     35GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
235P40809    384   RG84C_DROME GTPase-activating protein RacGAP8...1760.002     45.4     23     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IDA:FlyBase.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001745; P:compound eye morphogenesis; IMP:FlyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007283; P:spermatogenesis; IMP:FlyBase.
236Q8JFQ2    155   RBTN1_DANRE Rhombotin-1 OS=Danio rerio (Zebra...1100.002     43.1     23     35GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
237Q3B8H4    156   RBTN1_XENLA Rhombotin-1 OS=Xenopus laevis (Af...1100.002     43.1     23     35GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
238Q924W9    156   RBTN1_MOUSE Rhombotin-1 OS=Mus musculus (Mous...1100.002     43.1     23     35GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
239P25800    156   RBTN1_HUMAN Rhombotin-1 OS=Homo sapiens (Huma...1100.002     43.1     23     35GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
240Q54QF4    909   MGP4_DICDI Mental retardation GTPase activati...2190.002     45.8     20     44GO:0000331; C:contractile vacuole; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
241Q9P2N2    729   RHG28_HUMAN Rho GTPase-activating protein 28 ...2110.002     45.8     24     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
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