rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | Q9R059 | 289 | FHL3_MOUSE Four and a half LIM domains protei... | 36 | 3.1 | 35 | 33 | 58 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 152 | A8WRJ2 | 752 | RRC1_CAEBR GTPase-activating protein rrc-1 OS... | 192 | 0.0000001 | 59.7 | 24 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 153 | Q8K2H3 | 851 | FA13B_MOUSE Protein FAM13B OS=Mus musculus (M... | 218 | 0.0000001 | 59.7 | 21 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 154 | Q9NYF5 | 915 | FA13B_HUMAN Protein FAM13B OS=Homo sapiens (H... | 218 | 0.0000001 | 59.7 | 21 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 155 | Q4R7A4 | 284 | FHL5_MACFA Four and a half LIM domains protei... | 104 | 0.012 | 42.4 | 25 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 156 | Q9H0H5 | 632 | RGAP1_HUMAN Rac GTPase-activating protein 1 O... | 173 | 0.0000001 | 58.9 | 25 | 46 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0097149; C:centralspindlin complex; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0051233; C:spindle midzone; IDA:UniProtKB. | | | | | | | | | | GO:0043014; F:alpha-tubulin binding; IDA:UniProtKB.::GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.::GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:UniProtKB.::GO:0007108; P:cytokinesis, initiation of separation; IMP:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0007018; P:microtubule-based movement; TAS:Reactome.::GO:0007405; P:neuroblast proliferation; ISS:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IDA:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007283; P:spermatogenesis; IEP:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; IDA:UniProtKB.::GO:0008272; P:sulfate transport; IDA:UniProtKB. | 157 | Q5TD97 | 284 | FHL5_HUMAN Four and a half LIM domains protei... | 101 | 0.15 | 38.9 | 24 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 158 | Q80Y19 | 987 | RHGBA_MOUSE Rho GTPase-activating protein 11A... | 183 | 0.0000002 | 59.3 | 25 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 159 | Q54MV3 | 906 | GACJ_DICDI Rho GTPase-activating protein gacJ... | 213 | 0.0000002 | 58.9 | 21 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 160 | Q55DW9 | 1043 | GACZ_DICDI Rho GTPase-activating protein gacZ... | 173 | 0.0000002 | 58.9 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 161 | Q2KI95 | 279 | FHL2_BOVIN Four and a half LIM domains protei... | 101 | 0.034 | 41.2 | 27 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 162 | Q55GP8 | 684 | GACO_DICDI Rho GTPase-activating protein gacO... | 198 | 0.0000002 | 58.5 | 24 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 163 | Q99N37 | 858 | RHG17_RAT Rho GTPase-activating protein 17 OS... | 190 | 0.0000002 | 58.5 | 23 | 42 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005626; C:insoluble fraction; IDA:MGI.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IDA:MGI.::GO:0017156; P:calcium ion-dependent exocytosis; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro. | 164 | O35115 | 279 | FHL2_RAT Four and a half LIM domains protein ... | 92 | 0.034 | 41.2 | 26 | 45 | GO:0031430; C:M band; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:RGD. | | | | | | | | | | GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 165 | Q3UIA2 | 846 | RHG17_MOUSE Rho GTPase-activating protein 17 ... | 190 | 0.0000003 | 58.5 | 23 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 166 | Q6ZM89 | 805 | RHG42_DANRE Rho GTPase-activating protein 42 ... | 200 | 0.0000003 | 58.2 | 25 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 167 | Q14192 | 279 | FHL2_HUMAN Four and a half LIM domains protei... | 92 | 0.035 | 40.8 | 26 | 47 | GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0009725; P:response to hormone stimulus; IMP:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 168 | O70433 | 279 | FHL2_MOUSE Four and a half LIM domains protei... | 92 | 0.038 | 40.8 | 26 | 45 | GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0055014; P:atrial cardiac muscle cell development; IEP:BHF-UCL.::GO:0060347; P:heart trabecula formation; IEP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IEP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0055015; P:ventricular cardiac muscle cell development; IEP:BHF-UCL. | 169 | Q54SL6 | 531 | GACQ_DICDI Rho GTPase-activating protein gacQ... | 210 | 0.0000004 | 57.4 | 23 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 170 | Q9PT60 | 655 | RBP1A_XENLA RalA-binding protein 1-A OS=Xenop... | 175 | 0.0000006 | 57 | 26 | 46 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0001702; P:gastrulation with mouth forming second; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IPI:UniProtKB. | 171 | Q2YDK0 | 284 | FHL5_BOVIN Four and a half LIM domains protei... | 76 | 2.8 | 35 | 22 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 172 | Q68EM7 | 881 | RHG17_HUMAN Rho GTPase-activating protein 17 ... | 190 | 0.0000007 | 57 | 23 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 173 | Q3KRB8 | 267 | RHGBB_HUMAN Rho GTPase-activating protein 11B... | 234 | 0.0000008 | 55.5 | 23 | 43 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 174 | A6NI28 | 874 | RHG42_HUMAN Rho GTPase-activating protein 42 ... | 206 | 0.000001 | 56.6 | 23 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 175 | B2RQE8 | 841 | RHG42_MOUSE Rho GTPase-activating protein 42 ... | 206 | 0.000001 | 56.2 | 23 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 176 | P38339 | 666 | RGD1_YEAST RHO GTPase-activating protein RGD1... | 188 | 0.000001 | 55.8 | 22 | 46 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005933; C:cellular bud; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IMP:SGD.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IMP:SGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:SGD.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IMP:SGD.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0007231; P:osmosensory signaling pathway; IGI:SGD.::GO:0001101; P:response to acid; IMP:SGD. | 177 | Q8BZ05 | 1703 | ARAP2_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 200 | 0.000001 | 56.2 | 25 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 178 | Q6REY9 | 1182 | RHG20_RAT Rho GTPase-activating protein 20 OS... | 191 | 0.000001 | 56.2 | 24 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; TAS:RGD. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; TAS:RGD.::GO:0007165; P:signal transduction; IEA:InterPro. | 179 | Q6IFT4 | 1182 | RHG20_MOUSE Rho GTPase-activating protein 20 ... | 191 | 0.000002 | 55.8 | 24 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 180 | Q19157 | 329 | PIN2_CAEEL LIM domain-containing protein pin-... | 102 | 0.49 | 37.7 | 26 | 44 | GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0043196; C:varicosity; IDA:WormBase. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 181 | Q15311 | 655 | RBP1_HUMAN RalA-binding protein 1 OS=Homo sap... | 175 | 0.000002 | 55.5 | 25 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IDA:UniProtKB. | | | | | | | | | | GO:0043492; F:ATPase activity, coupled to movement of substances; IDA:UniProtKB.::GO:0030675; F:Rac GTPase activator activity; IDA:UniProtKB.::GO:0048365; F:Rac GTPase binding; IPI:UniProtKB.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB. | | | | | | | | | | GO:0006935; P:chemotaxis; TAS:ProtInc.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IPI:UniProtKB.::GO:0006810; P:transport; IDA:UniProtKB. |