Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR127W
Length:
1007
Number of sequences:
5887
Description:
YOR127W RGA1 SGDID:S000005653, Chr XV from 561170-564193, Genome Release 64-1-1, Verified ORF, "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q9R059    289   FHL3_MOUSE Four and a half LIM domains protei...363.1     35     33     58
GO:0008270; F:zinc ion binding; IEA:InterPro.
152A8WRJ2    752   RRC1_CAEBR GTPase-activating protein rrc-1 OS...1920.0000001     59.7     24     44GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; ISS:UniProtKB.
GO:0007165; P:signal transduction; IEA:InterPro.
153Q8K2H3    851   FA13B_MOUSE Protein FAM13B OS=Mus musculus (M...2180.0000001     59.7     21     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
154Q9NYF5    915   FA13B_HUMAN Protein FAM13B OS=Homo sapiens (H...2180.0000001     59.7     21     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
155Q4R7A4    284   FHL5_MACFA Four and a half LIM domains protei...1040.012     42.4     25     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
156Q9H0H5    632   RGAP1_HUMAN Rac GTPase-activating protein 1 O...1730.0000001     58.9     25     46GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0097149; C:centralspindlin complex; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0051233; C:spindle midzone; IDA:UniProtKB.
GO:0043014; F:alpha-tubulin binding; IDA:UniProtKB.::GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.::GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:UniProtKB.::GO:0007108; P:cytokinesis, initiation of separation; IMP:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0007018; P:microtubule-based movement; TAS:Reactome.::GO:0007405; P:neuroblast proliferation; ISS:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IDA:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007283; P:spermatogenesis; IEP:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; IDA:UniProtKB.::GO:0008272; P:sulfate transport; IDA:UniProtKB.
157Q5TD97    284   FHL5_HUMAN Four and a half LIM domains protei...1010.15     38.9     24     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
158Q80Y19    987   RHGBA_MOUSE Rho GTPase-activating protein 11A...1830.0000002     59.3     25     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
159Q54MV3    906   GACJ_DICDI Rho GTPase-activating protein gacJ...2130.0000002     58.9     21     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
160Q55DW9    1043   GACZ_DICDI Rho GTPase-activating protein gacZ...1730.0000002     58.9     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
161Q2KI95    279   FHL2_BOVIN Four and a half LIM domains protei...1010.034     41.2     27     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
162Q55GP8    684   GACO_DICDI Rho GTPase-activating protein gacO...1980.0000002     58.5     24     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
163Q99N37    858   RHG17_RAT Rho GTPase-activating protein 17 OS...1900.0000002     58.5     23     42GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005626; C:insoluble fraction; IDA:MGI.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007015; P:actin filament organization; IDA:MGI.::GO:0017156; P:calcium ion-dependent exocytosis; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.
164O35115    279   FHL2_RAT Four and a half LIM domains protein ...920.034     41.2     26     45GO:0031430; C:M band; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:RGD.
GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
165Q3UIA2    846   RHG17_MOUSE Rho GTPase-activating protein 17 ...1900.0000003     58.5     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
166Q6ZM89    805   RHG42_DANRE Rho GTPase-activating protein 42 ...2000.0000003     58.2     25     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
167Q14192    279   FHL2_HUMAN Four and a half LIM domains protei...920.035     40.8     26     47GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0009725; P:response to hormone stimulus; IMP:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
168O70433    279   FHL2_MOUSE Four and a half LIM domains protei...920.038     40.8     26     45GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0055014; P:atrial cardiac muscle cell development; IEP:BHF-UCL.::GO:0060347; P:heart trabecula formation; IEP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IEP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0055015; P:ventricular cardiac muscle cell development; IEP:BHF-UCL.
169Q54SL6    531   GACQ_DICDI Rho GTPase-activating protein gacQ...2100.0000004     57.4     23     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
170Q9PT60    655   RBP1A_XENLA RalA-binding protein 1-A OS=Xenop...1750.0000006     57     26     46GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0001702; P:gastrulation with mouth forming second; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IPI:UniProtKB.
171Q2YDK0    284   FHL5_BOVIN Four and a half LIM domains protei...762.8     35     22     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
172Q68EM7    881   RHG17_HUMAN Rho GTPase-activating protein 17 ...1900.0000007     57     23     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
173Q3KRB8    267   RHGBB_HUMAN Rho GTPase-activating protein 11B...2340.0000008     55.5     23     43GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
174A6NI28    874   RHG42_HUMAN Rho GTPase-activating protein 42 ...2060.000001     56.6     23     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
175B2RQE8    841   RHG42_MOUSE Rho GTPase-activating protein 42 ...2060.000001     56.2     23     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
176P38339    666   RGD1_YEAST RHO GTPase-activating protein RGD1...1880.000001     55.8     22     46GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005933; C:cellular bud; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IMP:SGD.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IMP:SGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:SGD.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IMP:SGD.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:SGD.
GO:0007231; P:osmosensory signaling pathway; IGI:SGD.::GO:0001101; P:response to acid; IMP:SGD.
177Q8BZ05    1703   ARAP2_MOUSE Arf-GAP with Rho-GAP domain, ANK ...2000.000001     56.2     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
178Q6REY9    1182   RHG20_RAT Rho GTPase-activating protein 20 OS...1910.000001     56.2     24     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; TAS:RGD.
GO:0035023; P:regulation of Rho protein signal transduction; TAS:RGD.::GO:0007165; P:signal transduction; IEA:InterPro.
179Q6IFT4    1182   RHG20_MOUSE Rho GTPase-activating protein 20 ...1910.000002     55.8     24     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
180Q19157    329   PIN2_CAEEL LIM domain-containing protein pin-...1020.49     37.7     26     44GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0043196; C:varicosity; IDA:WormBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
181Q15311    655   RBP1_HUMAN RalA-binding protein 1 OS=Homo sap...1750.000002     55.5     25     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IDA:UniProtKB.
GO:0043492; F:ATPase activity, coupled to movement of substances; IDA:UniProtKB.::GO:0030675; F:Rac GTPase activator activity; IDA:UniProtKB.::GO:0048365; F:Rac GTPase binding; IPI:UniProtKB.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB.
GO:0006935; P:chemotaxis; TAS:ProtInc.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IPI:UniProtKB.::GO:0006810; P:transport; IDA:UniProtKB.
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